GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name ▲ UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • Psmc1
10090
2
  • ATP binding
  • ATP hydrolysis activity
  • TBP-class protein binding
  • cytosol
  • membrane
  • nucleoplasm
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • GO:0000502
  • GO:0005524
  • GO:0005654
  • GO:0005829
  • GO:0005838
  • GO:0008540
  • GO:0016020
  • GO:0016887
  • GO:0017025
  • GO:0022624
  • GO:0036402
  • GO:0043161
  • PSMC3
9606
  • ATP binding
  • ATP hydrolysis activity
  • P-body
  • cytosol
  • extracellular region
  • ficolin-1-rich granule lumen
  • identical protein binding
  • membrane
  • modulation by host of viral transcription
  • nucleoplasm
  • nucleus
  • positive regulation of proteasomal protein catabolic process
  • positive regulation of transcription by RNA polymerase II
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • secretory granule lumen
  • GO:0000502
  • GO:0000932
  • GO:0005524
  • GO:0005576
  • GO:0005634
  • GO:0005654
  • GO:0005829
  • GO:0008540
  • GO:0016020
  • GO:0016887
  • GO:0022624
  • GO:0034774
  • GO:0036402
  • GO:0042802
  • GO:0043161
  • GO:0043921
  • GO:0045944
  • GO:1901800
  • GO:1904813
  • Psmc4
10090
  • ATP binding
  • ATP hydrolysis activity
  • blastocyst development
  • cytosol
  • cytosolic proteasome complex
  • inclusion body
  • nucleoplasm
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • synapse
  • GO:0000502
  • GO:0001824
  • GO:0005524
  • GO:0005654
  • GO:0005829
  • GO:0008540
  • GO:0016234
  • GO:0016887
  • GO:0022624
  • GO:0031597
  • GO:0036402
  • GO:0043161
  • GO:0045202
  • PSMC4
9606
2
  • ATP binding
  • ATP hydrolysis activity
  • blastocyst development
  • cytosol
  • membrane
  • nucleoplasm
  • nucleus
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • proteolysis
  • GO:0000502
  • GO:0001824
  • GO:0005524
  • GO:0005634
  • GO:0005654
  • GO:0005829
  • GO:0006508
  • GO:0008540
  • GO:0016020
  • GO:0016887
  • GO:0022624
  • GO:0036402
  • GO:0043161
  • Psmc2
10090
  • ATP binding
  • ATP hydrolysis activity
  • P-body
  • TBP-class protein binding
  • cytoplasmic ribonucleoprotein granule
  • cytosol
  • dendritic spine
  • general transcription initiation factor binding
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • ubiquitin-dependent protein catabolic process
  • GO:0000502
  • GO:0000932
  • GO:0005524
  • GO:0005829
  • GO:0006511
  • GO:0008540
  • GO:0016887
  • GO:0017025
  • GO:0022624
  • GO:0036402
  • GO:0036464
  • GO:0043161
  • GO:0043197
  • GO:0140296
  • PSMC2
9606
  • ATP binding
  • ATP hydrolysis activity
  • P-body
  • cytoplasm
  • cytoplasmic ribonucleoprotein granule
  • cytosol
  • extracellular region
  • ficolin-1-rich granule lumen
  • membrane
  • nucleoplasm
  • nucleus
  • osteoblast differentiation
  • positive regulation of proteasomal protein catabolic process
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • secretory granule lumen
  • ubiquitin-dependent protein catabolic process
  • GO:0000502
  • GO:0000932
  • GO:0001649
  • GO:0005524
  • GO:0005576
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0005829
  • GO:0006511
  • GO:0008540
  • GO:0016020
  • GO:0016887
  • GO:0022624
  • GO:0034774
  • GO:0036402
  • GO:0036464
  • GO:0043161
  • GO:1901800
  • GO:1904813
  • PSMC5
9606
1
  • ATP binding
  • ATP hydrolysis activity
  • DNA-binding transcription factor binding
  • blood microparticle
  • cytoplasm
  • cytoplasmic vesicle
  • cytosol
  • extracellular exosome
  • general transcription initiation factor binding
  • membrane
  • negative regulation of DNA-templated transcription
  • negative regulation of programmed cell death
  • nucleoplasm
  • nucleus
  • positive regulation of DNA-templated transcription
  • positive regulation of proteasomal protein catabolic process
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • regulation of transcription by RNA polymerase II
  • thyrotropin-releasing hormone receptor binding
  • transcription factor binding
  • GO:0000502
  • GO:0005524
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0005829
  • GO:0006357
  • GO:0008134
  • GO:0008540
  • GO:0016020
  • GO:0016887
  • GO:0022624
  • GO:0031410
  • GO:0031531
  • GO:0036402
  • GO:0043069
  • GO:0043161
  • GO:0045892
  • GO:0045893
  • GO:0070062
  • GO:0072562
  • GO:0140296
  • GO:0140297
  • GO:1901800
  • Psmc5
10090
1
  • ATP binding
  • ATP hydrolysis activity
  • DNA-binding transcription factor binding
  • TBP-class protein binding
  • cytoplasm
  • cytoplasmic vesicle
  • cytosolic proteasome complex
  • general transcription initiation factor binding
  • inclusion body
  • modulation of chemical synaptic transmission
  • negative regulation of DNA-templated transcription
  • nuclear proteasome complex
  • nucleus
  • positive regulation of inclusion body assembly
  • postsynapse
  • proteasome accessory complex
  • proteasome complex
  • proteasome regulatory particle
  • proteasome regulatory particle, base subcomplex
  • proteasome-activating activity
  • proteasome-mediated ubiquitin-dependent protein catabolic process
  • regulation of transcription by RNA polymerase II
  • signaling receptor binding
  • thyrotropin-releasing hormone receptor binding
  • transcription factor TFIIH holo complex
  • GO:0000502
  • GO:0005102
  • GO:0005524
  • GO:0005634
  • GO:0005675
  • GO:0005737
  • GO:0005838
  • GO:0006357
  • GO:0008540
  • GO:0016234
  • GO:0016887
  • GO:0017025
  • GO:0022624
  • GO:0031410
  • GO:0031531
  • GO:0031595
  • GO:0031597
  • GO:0036402
  • GO:0043161
  • GO:0045892
  • GO:0050804
  • GO:0090261
  • GO:0098794
  • GO:0140296
  • GO:0140297
  • Ank3
10090
1
  • cytoskeleton
  • localization
  • membrane
  • signal transduction
  • GO:0005856
  • GO:0007165
  • GO:0016020
  • GO:0051179
  • BN1205_068530
432359
Displaying entries 271 - 280 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01