GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Envelope glycoprotein gp160	P20872	env	Human immunodeficiency virus type 2 (ISOLATE ST)	11721	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane host cell endosome membrane host cell plasma membrane membrane structural molecule activity suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway viral envelope virion attachment to host cell virion membrane	GO:0005198 GO:0016020 GO:0019031 GO:0019062 GO:0020002 GO:0039502 GO:0039587 GO:0039654 GO:0044175 GO:0055036 GO:0075512
Alpha-tectorin	O75443	TECTA	Homo sapiens	9606	30	auditory receptor cell stereocilium organization cell-matrix adhesion extracellular exosome extracellular matrix extracellular matrix structural constituent extracellular region plasma membrane sensory perception of sound side of membrane	GO:0005201 GO:0005576 GO:0005886 GO:0007160 GO:0007605 GO:0031012 GO:0060088 GO:0070062 GO:0098552
Spike glycoprotein	Q14EB0	S	Human coronavirus HKU1 (isolate N2)	443240	30	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane host cell plasma membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0020002 GO:0039654 GO:0044173 GO:0046813 GO:0055036 GO:0075509
Envelope glycoprotein gp160	Q9QBY2	env	HIV-1 M:K_96CM-MP535	388906	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Spike glycoprotein	P12722	S	Avian infectious bronchitis virus (strain D274)	11124	30	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0039654 GO:0044173 GO:0046813 GO:0055036 GO:0075509
Envelope glycoprotein gp160	P05879	env	Human immunodeficiency virus type 1 (CDC-451 ISOLATE)	11687	30	clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0044175 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911
Spike glycoprotein	Q0ZME7	S	Human coronavirus HKU1 (isolate N5)	443241	30	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane host cell plasma membrane identical protein binding membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0020002 GO:0039654 GO:0042802 GO:0044173 GO:0046813 GO:0055036 GO:0075509
SUN domain-containing protein 2	Q54MI3	sun2	Dictyostelium discoideum	44689	29	culmination involved in sorocarp development cytoplasm membrane mitotic cytokinesis nuclear membrane nucleus vacuole	GO:0000281 GO:0005634 GO:0005737 GO:0005773 GO:0016020 GO:0031154 GO:0031965
Mucin-like protein Glc1.8b	Q4ZJY7	O16	Microplitis demolitor bracovirus (isolate Webb)	654919	29	host cell membrane membrane suppression by virus of host innate immune response	GO:0016020 GO:0033644 GO:0039503
Integrin alpha-1	P56199	ITGA1	Homo sapiens	9606	29	acrosomal vesicle basal part of cell cell adhesion mediated by integrin cell surface cell-cell adhesion cell-matrix adhesion cellular extravasation collagen binding collagen binding involved in cell-matrix adhesion external side of plasma membrane extracellular exosome focal adhesion integrin alpha1-beta1 complex integrin binding integrin complex integrin-mediated signaling pathway membrane metal ion binding negative regulation of cell population proliferation negative regulation of epidermal growth factor receptor signaling pathway neuron projection morphogenesis neutrophil chemotaxis perikaryon plasma membrane positive regulation of MAPK cascade positive regulation of neuron apoptotic process positive regulation of phosphoprotein phosphatase activity protein phosphatase binding vasodilation	GO:0001669 GO:0005178 GO:0005518 GO:0005886 GO:0005925 GO:0007160 GO:0007229 GO:0008285 GO:0008305 GO:0009897 GO:0009986 GO:0016020 GO:0019903 GO:0030593 GO:0032516 GO:0033627 GO:0034665 GO:0042059 GO:0042311 GO:0043204 GO:0043410 GO:0043525 GO:0045123 GO:0045178 GO:0046872 GO:0048812 GO:0070062 GO:0098609 GO:0098639