GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
Low-density lipoprotein receptor	P35950	LDLR	Cricetulus griseus	10029	3	Golgi apparatus calcium ion binding cell surface cholesterol metabolic process clathrin-coated pit early endosome endocytosis late endosome lipid transport low-density lipoprotein particle lysosome	GO:0005509 GO:0005764 GO:0005769 GO:0005770 GO:0005794 GO:0005905 GO:0006869 GO:0006897 GO:0008203 GO:0009986 GO:0034362
P2Y purinoceptor 4 (Fragment)	P58826	P2RY4	Cricetulus griseus	10029	1	G protein-coupled purinergic nucleotide receptor activity plasma membrane transepithelial chloride transport	GO:0005886 GO:0030321 GO:0045028
Voltage-dependent P/Q-type calcium channel subunit alpha	G3HCZ0	I79_008358	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Major prion protein	Q60506	PRNP	Cricetulus griseus	10029	2	Golgi apparatus amyloid-beta binding aspartic-type endopeptidase inhibitor activity calcium-mediated signaling using intracellular calcium source cell surface cellular response to amyloid-beta cellular response to copper ion cellular response to xenobiotic stimulus copper ion binding cupric ion binding cuprous ion binding cytosol dendrite endoplasmic reticulum glycosaminoglycan binding identical protein binding inclusion body learning or memory membrane raft microtubule binding molecular condensate scaffold activity molecular function activator activity negative regulation of T cell receptor signaling pathway negative regulation of activated T cell proliferation negative regulation of amyloid-beta formation negative regulation of apoptotic process negative regulation of calcineurin-NFAT signaling cascade negative regulation of dendritic spine maintenance negative regulation of interleukin-17 production negative regulation of interleukin-2 production negative regulation of protein phosphorylation negative regulation of type II interferon production neuron projection maintenance nuclear membrane plasma membrane positive regulation of neuron apoptotic process positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein localization to plasma membrane positive regulation of protein targeting to membrane protease binding protein destabilization protein homooligomerization protein sequestering activity protein-containing complex binding regulation of calcium ion import across plasma membrane regulation of glutamate receptor signaling pathway regulation of potassium ion transmembrane transport response to oxidative stress side of membrane signaling receptor activity terminal bouton type 5 metabotropic glutamate receptor binding	GO:0001540 GO:0001933 GO:0002020 GO:0005507 GO:0005539 GO:0005783 GO:0005794 GO:0005829 GO:0005886 GO:0006979 GO:0007611 GO:0008017 GO:0009986 GO:0016234 GO:0019828 GO:0030425 GO:0031648 GO:0031802 GO:0031965 GO:0032689 GO:0032700 GO:0032703 GO:0035584 GO:0038023 GO:0042802 GO:0043066 GO:0043195 GO:0043525 GO:0044877 GO:0045121 GO:0046007 GO:0050731 GO:0050860 GO:0051260 GO:0070885 GO:0071280 GO:0071466 GO:0090314 GO:0098552 GO:0140311 GO:0140677 GO:0140693 GO:1900449 GO:1901379 GO:1902430 GO:1902951 GO:1903078 GO:1903135 GO:1903136 GO:1904646 GO:1905664 GO:1990535
Hypoxia up-regulated protein 1	Q60432	HYOU1	Cricetulus griseus	10029	9	ATP binding ATP-dependent protein folding chaperone endoplasmic reticulum lumen	GO:0005524 GO:0005788 GO:0140662
Post-GPI attachment to proteins factor 3	A2V7M9	PGAP3	Cricetulus griseus	10029	1	GPI anchor metabolic process Golgi membrane endoplasmic reticulum membrane hydrolase activity, acting on ester bonds	GO:0000139 GO:0005789 GO:0006505 GO:0016788
A disintegrin and metalloproteinase with thrombospondin motifs 5	G3I3J4	I79_018002	Cricetulus griseus	10029	2	collagen-containing extracellular matrix extracellular matrix organization extracellular region integrin-mediated signaling pathway metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0007229 GO:0008270 GO:0030198 GO:0062023
Phosphoinositide phospholipase C	A0A8C2M9P5	Plcd1	Cricetulus griseus	10029	2	calcium ion binding intracellular signal transduction lipid catabolic process phosphatidylinositol phospholipase C activity	GO:0004435 GO:0005509 GO:0016042 GO:0035556
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	P24140	DPAGT1	Cricetulus griseus	10029	1	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity dolichol biosynthetic process dolichol-linked oligosaccharide biosynthetic process endoplasmic reticulum membrane glycosyltransferase activity identical protein binding membrane metal ion binding	GO:0003975 GO:0003976 GO:0005789 GO:0006488 GO:0016020 GO:0016757 GO:0019408 GO:0042802 GO:0046872
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A061I8L4	H671_3g9658	Cricetulus griseus	10029	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872