GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Spike glycoprotein	P12650	S	Avian infectious bronchitis virus (strain KB8523)	11126	29	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0039654 GO:0044173 GO:0046813 GO:0055036 GO:0075509
Trehalose synthase complex regulatory subunit TPS3	P38426	TPS3	Saccharomyces cerevisiae S288C	559292	29	alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) catalytic activity cytoplasm enzyme regulator activity identical protein binding trehalose biosynthetic process trehalose metabolism in response to stress	GO:0003824 GO:0005737 GO:0005946 GO:0005992 GO:0030234 GO:0042802 GO:0070413
Collagen alpha-1(XII) chain	Q99715	COL12A1	Homo sapiens	9606	29	cell adhesion collagen fibril organization collagen type XII trimer collagen-containing extracellular matrix endodermal cell differentiation endoplasmic reticulum lumen extracellular exosome extracellular matrix structural constituent conferring tensile strength extracellular region extracellular space extracellular vesicle	GO:0005576 GO:0005595 GO:0005615 GO:0005788 GO:0007155 GO:0030020 GO:0030199 GO:0035987 GO:0062023 GO:0070062 GO:1903561
Lysophospholipase 2	Q03674	PLB2	Saccharomyces cerevisiae S288C	559292	29	cell periphery cytosol extracellular region fungal-type cell wall glycerophospholipid catabolic process glycerophospholipid metabolic process intracellular membrane-bounded organelle lysophospholipase activity phosphatidyl phospholipase B activity phospholipase A2 activity plasma membrane side of membrane	GO:0004622 GO:0004623 GO:0005576 GO:0005829 GO:0005886 GO:0006650 GO:0009277 GO:0043231 GO:0046475 GO:0071944 GO:0098552 GO:0102545
Cadherin EGF LAG seven-pass G-type receptor 1	Q9NYQ6	CELSR1	Homo sapiens	9606	29	G protein-coupled receptor activity Rho protein signal transduction Wnt signaling pathway, planar cell polarity pathway apical protein localization calcium ion binding cell-cell adhesion central nervous system development establishment of body hair planar orientation establishment of planar polarity establishment of planar polarity of embryonic epithelium homophilic cell adhesion via plasma membrane adhesion molecules lateral sprouting involved in lung morphogenesis membrane neural tube closure neuron migration nucleoplasm orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis planar dichotomous subdivision of terminal units involved in lung branching morphogenesis plasma membrane protein localization involved in establishment of planar polarity regulation of actin cytoskeleton organization	GO:0001736 GO:0001764 GO:0001843 GO:0004930 GO:0005509 GO:0005654 GO:0005886 GO:0007156 GO:0007266 GO:0007417 GO:0016020 GO:0032956 GO:0042249 GO:0045176 GO:0048105 GO:0060071 GO:0060488 GO:0060489 GO:0060490 GO:0090251 GO:0098609
Spike glycoprotein	P12651	S	Avian infectious bronchitis virus (strain M41)	11127	29	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endoplasmic reticulum-Golgi intermediate compartment membrane membrane receptor-mediated virion attachment to host cell viral envelope virion membrane	GO:0016020 GO:0019031 GO:0019064 GO:0039654 GO:0044173 GO:0046813 GO:0055036 GO:0075509
Plasma protease C1 inhibitor	P05155	SERPING1	Homo sapiens	9606	29	blood circulation blood coagulation blood microparticle collagen-containing extracellular matrix complement activation, classical pathway endoplasmic reticulum lumen extracellular exosome extracellular region extracellular space fibrinolysis innate immune response negative regulation of complement activation, lectin pathway platelet alpha granule lumen serine-type endopeptidase inhibitor activity	GO:0001869 GO:0004867 GO:0005576 GO:0005615 GO:0005788 GO:0006958 GO:0007596 GO:0008015 GO:0031093 GO:0042730 GO:0045087 GO:0062023 GO:0070062 GO:0072562
Major surface glycoprotein G	P27021	G	Human respiratory syncytial virus (strain RSB642)	11252	29	extracellular region host cell plasma membrane membrane viral entry into host cell virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005576 GO:0016020 GO:0019049 GO:0019062 GO:0020002 GO:0046718 GO:0055036
Coagulation factor VIII	O18806	F8	Canis lupus familiaris	9615	29	acute-phase response blood coagulation, intrinsic pathway copper ion binding extracellular space oxidoreductase activity	GO:0005507 GO:0005615 GO:0006953 GO:0007597 GO:0016491
Envelope glycoprotein gp160	P04578	env	HIV-1 M:B_HXB2R	11706	29	actin filament organization clathrin-dependent endocytosis of virus by host cell evasion of host immune response fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell endosome membrane host cell plasma membrane membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering structural molecule activity viral entry into host cell viral envelope viral protein processing virion attachment to host cell virion membrane virus-mediated perturbation of host defense response	GO:0005198 GO:0007015 GO:0016020 GO:0019031 GO:0019049 GO:0019062 GO:0019064 GO:0019082 GO:0020002 GO:0039654 GO:0042783 GO:0044175 GO:0046718 GO:0055036 GO:0075512 GO:1903905 GO:1903908 GO:1903911