GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
3'-5' RNA helicase YTHDC2	Q9H6S0	YTHDC2	Homo sapiens	9606		3'-5' RNA helicase activity ATP binding ATP hydrolysis activity ATP-dependent activity, acting on RNA N6-methyladenosine-containing RNA reader activity RNA binding RNA polymerase binding endoplasmic reticulum germline cell cycle switching, mitotic to meiotic cell cycle helicase activity meiotic cell cycle oocyte development perinuclear region of cytoplasm positive regulation by host of viral genome replication response to interleukin-1 response to tumor necrosis factor ribonucleoprotein granule spermatid development	GO:0003723 GO:0004386 GO:0005524 GO:0005783 GO:0007286 GO:0008186 GO:0016887 GO:0034458 GO:0034612 GO:0035770 GO:0044829 GO:0048471 GO:0048599 GO:0051321 GO:0051729 GO:0070063 GO:0070555 GO:1990247
3'-5' exonuclease domain-containing protein	Q21251	CELE_K05G3.1	Caenorhabditis elegans	6239	1	3'-5' exonuclease activity nucleic acid binding nucleobase-containing compound metabolic process regulation of macromolecule metabolic process	GO:0003676 GO:0006139 GO:0008408 GO:0060255
3'-phosphoadenosine 5'-phosphosulfate synthase 2	A0A494B923	Papss2	Mus musculus	10090		ATP binding adenylylsulfate kinase activity purine nucleoside bisphosphate biosynthetic process purine ribonucleotide biosynthetic process ribonucleoside bisphosphate biosynthetic process sulfate adenylyltransferase (ATP) activity sulfate assimilation	GO:0000103 GO:0004020 GO:0004781 GO:0005524 GO:0009152 GO:0034030 GO:0034033
3,2-trans-enoyl-CoA isomerase	V5B2L9	TCDM_10529	Trypanosoma cruzi Dm28c	1416333		isomerase activity membrane	GO:0016020 GO:0016853
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase	Q5KA65	XPT1	Cryptococcus neoformans var. neoformans JEC21	214684	2	D-xylose metabolic process Golgi apparatus Golgi membrane N-glycan processing to lysosome UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity carbohydrate phosphorylation glycosyltransferase activity	GO:0000139 GO:0003976 GO:0005794 GO:0016256 GO:0016757 GO:0042732 GO:0046835
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase	F5HID8	XPT1	Cryptococcus neoformans var. neoformans B-3501A	283643	2	D-xylose metabolic process Golgi membrane glycosyltransferase activity	GO:0000139 GO:0016757 GO:0042732
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase	D0U690	XPT1	Cryptococcus neoformans var. grubii	178876	3	D-xylose metabolic process Golgi membrane glycosyltransferase activity	GO:0000139 GO:0016757 GO:0042732
3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase	E6RCE9	XPT1	Cryptococcus gattii WM276	367775	2	D-xylose metabolic process Golgi membrane glycosyltransferase activity	GO:0000139 GO:0016757 GO:0042732
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	Q15125	EBP	Homo sapiens	9606	3	C-8 sterol isomerase activity cholestenol delta-isomerase activity cholesterol biosynthetic process cholesterol biosynthetic process via desmosterol cholesterol biosynthetic process via lathosterol cholesterol metabolic process cytoplasmic vesicle endoplasmic reticulum endoplasmic reticulum membrane hemopoiesis identical protein binding nuclear envelope nuclear membrane ossification involved in bone maturation steroid delta-isomerase activity	GO:0000247 GO:0004769 GO:0005635 GO:0005783 GO:0005789 GO:0006695 GO:0008203 GO:0030097 GO:0031410 GO:0031965 GO:0033489 GO:0033490 GO:0042802 GO:0043931 GO:0047750
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	P70245	Ebp	Mus musculus	10090	1	C-8 sterol isomerase activity cholestenol delta-isomerase activity cholesterol biosynthetic process cholesterol metabolic process cytoplasmic vesicle endoplasmic reticulum endoplasmic reticulum membrane hemopoiesis identical protein binding intracellular membrane-bounded organelle nuclear envelope nuclear membrane ossification involved in bone maturation steroid delta-isomerase activity sterol biosynthetic process	GO:0000247 GO:0004769 GO:0005635 GO:0005783 GO:0005789 GO:0006695 GO:0008203 GO:0016126 GO:0030097 GO:0031410 GO:0031965 GO:0042802 GO:0043231 GO:0043931 GO:0047750