GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
3-dehydrosphinganine reductase	K2MAZ3	MOQ_003824	Trypanosoma cruzi marinkellei	85056		3-dehydrosphinganine reductase activity 3-keto-sphinganine metabolic process sphingolipid biosynthetic process	GO:0006666 GO:0030148 GO:0047560
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3	Q8HYJ5	FUT3	Pongo pygmaeus	9600	2	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Golgi cisterna membrane fucosylation lipid metabolic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell population proliferation	GO:0006487 GO:0006493 GO:0006629 GO:0009311 GO:0017060 GO:0017083 GO:0022409 GO:0030334 GO:0032580 GO:0036065 GO:0042127
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3	P21217	FUT3	Homo sapiens	9606	2	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Golgi cisterna membrane Golgi membrane alpha-(1->3)-fucosyltransferase activity cell-cell recognition ceramide metabolic process extracellular exosome fucosylation fucosyltransferase activity macromolecule glycosylation membrane oligosaccharide biosynthetic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell population proliferation	GO:0000139 GO:0006487 GO:0006493 GO:0006672 GO:0008417 GO:0009311 GO:0009312 GO:0009988 GO:0016020 GO:0017060 GO:0017083 GO:0022409 GO:0030334 GO:0032580 GO:0036065 GO:0042127 GO:0043413 GO:0046920 GO:0070062
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3	Q11126	FUT3	Bos taurus	9913	3	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Golgi cisterna membrane alpha-(1->3)-fucosyltransferase activity fucosylation lipid metabolic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell population proliferation	GO:0006487 GO:0006493 GO:0006629 GO:0009311 GO:0017060 GO:0017083 GO:0022409 GO:0030334 GO:0032580 GO:0036065 GO:0042127 GO:0046920
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3	O19058	FUT3	Pan troglodytes	9598	2	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Golgi cisterna membrane alpha-(1->3)-fucosyltransferase activity fucosylation lipid metabolic process oligosaccharide metabolic process positive regulation of cell-cell adhesion protein N-linked glycosylation protein O-linked glycosylation regulation of cell migration regulation of cell population proliferation	GO:0006487 GO:0006493 GO:0006629 GO:0009311 GO:0017060 GO:0017083 GO:0022409 GO:0030334 GO:0032580 GO:0036065 GO:0042127 GO:0046920
3-hydroxy-3-methylglutaryl coenzyme A reductase	F2Z470	Hmgcr	Mus musculus	10090	1	NADP binding cholesterol biosynthetic process coenzyme A metabolic process endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity isoprenoid biosynthetic process peroxisomal membrane	GO:0004420 GO:0005778 GO:0005789 GO:0006695 GO:0008299 GO:0015936 GO:0050661
3-hydroxy-3-methylglutaryl coenzyme A reductase	V5B780	TCDM_02105	Trypanosoma cruzi Dm28c	1416333		coenzyme A metabolic process endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity isoprenoid biosynthetic process	GO:0004420 GO:0005789 GO:0008299 GO:0015936
3-hydroxy-3-methylglutaryl coenzyme A reductase 1	A0A0A1C3I2	HMGR1	Panax ginseng	4054	1	chloroplast membrane coenzyme A metabolic process endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity peroxisomal membrane response to absence of light response to jasmonic acid saponin biosynthetic process triterpenoid biosynthetic process	GO:0004420 GO:0005778 GO:0005789 GO:0009646 GO:0009753 GO:0015936 GO:0016104 GO:0016135 GO:0031969
3-hydroxy-3-methylglutaryl coenzyme A reductase 2-A	A0A0A1C930	HMGR2	Panax ginseng	4054	2	chloroplast membrane coenzyme A metabolic process endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity peroxisomal membrane response to jasmonic acid saponin biosynthetic process triterpenoid biosynthetic process	GO:0004420 GO:0005778 GO:0005789 GO:0009753 GO:0015936 GO:0016104 GO:0016135 GO:0031969
3-hydroxy-3-methylglutaryl coenzyme A reductase 2-B	U5JCC6	HMGR2	Panax ginseng	4054	2	coenzyme A metabolic process endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity isoprenoid biosynthetic process	GO:0004420 GO:0005789 GO:0008299 GO:0015936