GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
CD44 antigen	P20944	CD44	Cricetulus griseus	10029	8	apical plasma membrane cell adhesion cell projection extracellular region hyaluronic acid binding lamellipodium membrane microvillus plasma membrane regulation of lamellipodium morphogenesis wound healing, spreading of cells	GO:0005540 GO:0005576 GO:0005886 GO:0005902 GO:0007155 GO:0016324 GO:0031258 GO:0042995 GO:0044319 GO:2000392
Lysosome-associated membrane glycoprotein 1	P49129	LAMP1	Cricetulus griseus	10029	21	cytolytic granule membrane endosome membrane late endosome membrane lysosomal membrane lysosome plasma membrane protein stabilization	GO:0005764 GO:0005765 GO:0005886 GO:0010008 GO:0031902 GO:0050821 GO:0101004
ADAM metallopeptidase with thrombospondin type 1 motif 5	A0A8C2LCH6	Adamts5	Cricetulus griseus	10029	2	collagen-containing extracellular matrix extracellular matrix organization extracellular region metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0030198 GO:0062023
Ileal sodium/bile acid cotransporter	Q60414	SLC10A2	Cricetulus griseus	10029	2	lipid transport membrane sodium ion transport symporter activity	GO:0006814 GO:0006869 GO:0015293 GO:0016020
EGF-containing fibulin-like extracellular matrix protein 2	O55058	EFEMP2	Cricetulus griseus	10029	2	aorta development aorta smooth muscle tissue morphogenesis basement membrane calcium ion binding elastic fiber elastic fiber assembly extracellular matrix extracellular region heparin binding microfibril negative regulation of vascular associated smooth muscle cell proliferation positive regulation of aortic smooth muscle cell differentiation positive regulation of collagen fibril organization positive regulation of smooth muscle cell-matrix adhesion protein homodimerization activity regulation of collagen fibril organization vascular associated smooth muscle cell development	GO:0001527 GO:0005509 GO:0005576 GO:0005604 GO:0008201 GO:0031012 GO:0035904 GO:0042803 GO:0048251 GO:0060414 GO:0071953 GO:0097084 GO:1904026 GO:1904028 GO:1904706 GO:1904831 GO:1905609
Hyaluronidase	A0A8C2MJB4	Hyal1	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Heparan-sulfate 6-O-sulfotransferase 1	Q91ZB4	HS6ST1	Cricetulus griseus	10029	2	membrane neuron development sulfotransferase activity	GO:0008146 GO:0016020 GO:0048666
3-hydroxy-3-methylglutaryl-coenzyme A reductase	P00347	HMGCR	Cricetulus griseus	10029	1	GTPase regulator activity NADPH binding cholesterol biosynthetic process coenzyme A binding coenzyme A metabolic process endoplasmic reticulum endoplasmic reticulum membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity isoprenoid biosynthetic process long-term synaptic potentiation negative regulation of amyloid-beta clearance negative regulation of protein catabolic process negative regulation of protein secretion peroxisomal membrane regulation of ERK1 and ERK2 cascade visual learning	GO:0004420 GO:0005778 GO:0005783 GO:0005789 GO:0006695 GO:0008299 GO:0008542 GO:0015936 GO:0030695 GO:0042177 GO:0050709 GO:0060291 GO:0070372 GO:0070402 GO:0120225 GO:1900222
Sterol regulatory element-binding protein cleavage-activating protein	P97260	SCAP	Cricetulus griseus	10029	3	COPII-coated vesicle cargo loading ER to Golgi transport vesicle membrane Golgi membrane SREBP signaling pathway SREBP-SCAP complex SREBP-SCAP-Insig complex cellular response to sterol cholesterol metabolic process endoplasmic reticulum endoplasmic reticulum membrane membrane protein import into nucleus sterol binding vesicle coat	GO:0000139 GO:0005783 GO:0005789 GO:0006606 GO:0008203 GO:0012507 GO:0016020 GO:0030120 GO:0032933 GO:0032934 GO:0032936 GO:0032937 GO:0036315 GO:0090110
Paraoxonase	G3HT85	Pon1	Cricetulus griseus	10029	3	acyl-L-homoserine-lactone lactonohydrolase activity aromatic compound catabolic process aryldialkylphosphatase activity arylesterase activity calcium ion binding carboxylic acid catabolic process cholesterol metabolic process organophosphate catabolic process phosphatidylcholine metabolic process phospholipid binding positive regulation of cholesterol efflux protein homodimerization activity response to toxic substance spherical high-density lipoprotein particle	GO:0004063 GO:0004064 GO:0005509 GO:0005543 GO:0008203 GO:0009636 GO:0010875 GO:0019439 GO:0034366 GO:0042803 GO:0046395 GO:0046434 GO:0046470 GO:0102007