GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▼	No. of Glycosylation Sites	GO Labels	GO IDs
Myc proto-oncogene protein	Q9MZT6	MYC	Sylvilagus floridanus	9988	1	DNA damage response DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding G1/S transition of mitotic cell cycle MAPK cascade chromatin remodeling chromosome organization intracellular iron ion homeostasis negative regulation of cell division negative regulation of monocyte differentiation nucleolus nucleoplasm positive regulation of DNA-templated transcription positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of epithelial cell proliferation positive regulation of fibroblast proliferation positive regulation of transcription by RNA polymerase II protein dimerization activity protein-containing complex binding regulation of DNA-templated transcription regulation of somatic stem cell population maintenance regulation of telomere maintenance response to gamma radiation	GO:0000082 GO:0000165 GO:0000981 GO:0005654 GO:0005730 GO:0006338 GO:0006355 GO:0006879 GO:0006974 GO:0010332 GO:0032204 GO:0043280 GO:0044877 GO:0045656 GO:0045893 GO:0045944 GO:0046983 GO:0048146 GO:0050679 GO:0051276 GO:0051782 GO:0070888 GO:1904672
Antigen-presenting glycoprotein CD1d (Fragment)	P23043	CD1D	Sylvilagus floridanus	9988	4	basolateral plasma membrane endoplasmic reticulum membrane endosome membrane innate immune response lipid antigen binding lysosomal membrane lysosome	GO:0005764 GO:0005765 GO:0005789 GO:0010008 GO:0016323 GO:0030882 GO:0045087
Adenylate cyclase type 5	P40144	ADCY5	Oryctolagus cuniculus	9986	3	ATP binding adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP biosynthetic process cellular response to forskolin cilium intracellular signal transduction membrane metal ion binding plasma membrane positive regulation of cytosolic calcium ion concentration regulation of insulin secretion involved in cellular response to glucose stimulus	GO:0004016 GO:0005524 GO:0005886 GO:0005929 GO:0006171 GO:0007189 GO:0007204 GO:0016020 GO:0035556 GO:0046872 GO:0061178 GO:1904322
Polymeric immunoglobulin receptor	P01832	PIGR	Oryctolagus cuniculus	9986	3	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor plasma membrane secretory IgA immunoglobulin complex	GO:0002415 GO:0005886 GO:0071751
Calsequestrin-2	P31235	CASQ2	Oryctolagus cuniculus	9986	1	calcium ion binding sarcoplasmic reticulum sarcoplasmic reticulum lumen terminal cisterna	GO:0005509 GO:0014802 GO:0016529 GO:0033018
C-C chemokine receptor type 5	Q1ZY22	CCR5	Oryctolagus cuniculus	9986	2	C-C chemokine receptor activity chemotaxis external side of plasma membrane immune response inflammatory response	GO:0006935 GO:0006954 GO:0006955 GO:0009897 GO:0016493
Bone morphogenetic protein 4	O46576	BMP4	Oryctolagus cuniculus	9986	4	BMP receptor binding blood vessel endothelial cell proliferation involved in sprouting angiogenesis chondrocyte differentiation cytokine activity deltoid tuberosity development endochondral ossification extracellular space glomerular capillary formation growth factor activity heart induction hematopoietic progenitor cell differentiation kidney development lung vasculature development lymphoid progenitor cell differentiation negative regulation of branching involved in ureteric bud morphogenesis negative regulation of cell population proliferation negative regulation of glomerular mesangial cell proliferation negative regulation of immature T cell proliferation in thymus negative regulation of mesenchymal cell proliferation involved in ureter development negative regulation of metanephric S-shaped body morphogenesis negative regulation of metanephric comma-shaped body morphogenesis negative regulation of mitotic nuclear division negative regulation of thymocyte apoptotic process osteoblast differentiation positive chemotaxis positive regulation of BMP signaling pathway positive regulation of DNA-templated transcription positive regulation of branching involved in lung morphogenesis positive regulation of cardiac muscle fiber development positive regulation of cell population proliferation positive regulation of collagen biosynthetic process positive regulation of epidermal cell differentiation positive regulation of epithelial cell proliferation positive regulation of protein localization to nucleus regulation of cell fate commitment secondary heart field specification tendon cell differentiation type B pancreatic cell development	GO:0001649 GO:0001822 GO:0001958 GO:0002043 GO:0002062 GO:0002244 GO:0002320 GO:0003129 GO:0003139 GO:0003323 GO:0005125 GO:0005615 GO:0008083 GO:0008284 GO:0008285 GO:0010453 GO:0030513 GO:0032967 GO:0033088 GO:0035990 GO:0035993 GO:0045606 GO:0045839 GO:0045893 GO:0050679 GO:0050918 GO:0055020 GO:0060426 GO:0061047 GO:0070244 GO:0070700 GO:0072104 GO:0072125 GO:0072200 GO:0090191 GO:1900182 GO:2000005 GO:2000007
Zona pellucida sperm-binding protein 4	Q00193	ZP4	Oryctolagus cuniculus	9986	8	acrosin binding acrosomal vesicle exocytosis egg coat extracellular region identical protein binding negative regulation of binding of sperm to zona pellucida plasma membrane positive regulation of T cell proliferation positive regulation of acrosome reaction positive regulation of humoral immune response structural constituent of egg coat	GO:0002922 GO:0005576 GO:0005886 GO:0032190 GO:0035804 GO:0035805 GO:0042102 GO:0042802 GO:0060478 GO:2000344 GO:2000360
Very low-density lipoprotein receptor	P35953	VLDLR	Oryctolagus cuniculus	9986	3	apolipoprotein binding calcium ion binding calcium-dependent protein binding cholesterol metabolic process clathrin-coated pit dendrite morphogenesis glycoprotein transport lipid transport positive regulation of dendrite development receptor complex receptor-mediated endocytosis reelin receptor activity ventral spinal cord development very-low-density lipoprotein particle very-low-density lipoprotein particle binding very-low-density lipoprotein particle clearance very-low-density lipoprotein particle receptor activity	GO:0005509 GO:0005905 GO:0006869 GO:0006898 GO:0008203 GO:0021517 GO:0030229 GO:0034185 GO:0034189 GO:0034361 GO:0034436 GO:0034447 GO:0038025 GO:0043235 GO:0048306 GO:0048813 GO:1900006
UDP-glucuronosyltransferase 2C1 (Fragment)	P36514	UGT2C1	Oryctolagus cuniculus	9986	2	endoplasmic reticulum membrane glucuronosyltransferase activity lipid metabolic process	GO:0005789 GO:0006629 GO:0015020