GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID ▲	No. of Glycosylation Sites	GO Labels	GO IDs
Voltage-dependent L-type calcium channel subunit alpha	A0A8C2N1N1	Cacna1d	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Peptidyl-glycine alpha-amidating monooxygenase isoform X2	A0A8C2LV12	Pam	Cricetulus griseus	10029	1	L-ascorbic acid binding copper ion binding lyase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen peptide metabolic process transport vesicle membrane	GO:0005507 GO:0006518 GO:0016715 GO:0016829 GO:0030658 GO:0031418
P2X purinoceptor	A0A3L7HM64	P2rx2	Cricetulus griseus	10029	1	ATP binding apical plasma membrane behavioral response to pain detection of hypoxic conditions in blood by carotid body chemoreceptor signaling extracellularly ATP-gated monoatomic cation channel activity identical protein binding neuromuscular junction development neuromuscular synaptic transmission neuronal dense core vesicle peristalsis postsynapse purinergic nucleotide receptor activity receptor complex response to ATP response to carbohydrate response to hypoxia sensory perception of sound sensory perception of taste skeletal muscle fiber development urinary bladder smooth muscle contraction	GO:0001614 GO:0001666 GO:0003029 GO:0004931 GO:0005524 GO:0007274 GO:0007528 GO:0007605 GO:0009743 GO:0014832 GO:0016324 GO:0030432 GO:0033198 GO:0042802 GO:0043235 GO:0048266 GO:0048741 GO:0050909 GO:0098794 GO:0098992
Multidrug resistance protein 2	P21449	PGY2	Cricetulus griseus	10029	6	ABC-type xenobiotic transporter activity ATP binding ATP hydrolysis activity membrane	GO:0005524 GO:0008559 GO:0016020 GO:0016887
Protein adenylyltransferase FICD	A0A3L7HMF6	Ficd	Cricetulus griseus	10029	1	AMPylase activity ATP binding Hsp70 protein binding endoplasmic reticulum membrane protein homodimerization activity regulation of IRE1-mediated unfolded protein response response to endoplasmic reticulum stress	GO:0005524 GO:0005789 GO:0030544 GO:0034976 GO:0042803 GO:0070733 GO:1903894
Beta-secretase 2	A0A8C2LK34	Bace2	Cricetulus griseus	10029	2	aspartic-type endopeptidase activity endosome membrane proteolysis	GO:0004190 GO:0005768 GO:0006508 GO:0016020
5-hydroxytryptamine receptor 1B	P46636	HTR1B	Cricetulus griseus	10029	2	G protein-coupled serotonin receptor activity adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to xenobiotic stimulus chemical synaptic transmission negative regulation of serotonin secretion plasma membrane presynapse presynaptic modulation of chemical synaptic transmission regulation of behavior serotonergic synapse vasoconstriction	GO:0004993 GO:0005886 GO:0007198 GO:0007268 GO:0007610 GO:0014063 GO:0042310 GO:0046849 GO:0050795 GO:0071312 GO:0071466 GO:0098793 GO:0099154 GO:0099171
Legumain	G3I1H5	Lgmn	Cricetulus griseus	10029	3	apical part of cell associative learning cellular response to amyloid-beta cellular response to calcium ion cellular response to hepatocyte growth factor stimulus cysteine-type endopeptidase activity dendritic spine organization extracellular region late endosome lysosome memory negative regulation of ERBB signaling pathway negative regulation of gene expression negative regulation of multicellular organism growth negative regulation of neuron apoptotic process perinuclear region of cytoplasm positive regulation of cell population proliferation positive regulation of endothelial cell chemotaxis positive regulation of long-term synaptic potentiation positive regulation of mitotic cell cycle positive regulation of monocyte chemotaxis proteolysis involved in protein catabolic process receptor catabolic process renal system process response to acidic pH self proteolysis	GO:0003014 GO:0004197 GO:0005576 GO:0005764 GO:0005770 GO:0007613 GO:0008284 GO:0008306 GO:0010447 GO:0010629 GO:0032801 GO:0035729 GO:0040015 GO:0043524 GO:0045177 GO:0045931 GO:0048471 GO:0051603 GO:0071277 GO:0090026 GO:0097061 GO:0097264 GO:1900273 GO:1901185 GO:1904646 GO:2001028
Hyaluronidase	A0A061IIY5	H671_1g2597	Cricetulus griseus	10029	1	carbohydrate metabolic process hyalurononglucosaminidase activity membrane	GO:0004415 GO:0005975 GO:0016020
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	A0A061IFN8	H671_3g9495	Cricetulus griseus	10029	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872