GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID ▼ No. of Glycosylation Sites GO Labels GO IDs
  • HCN4
9986
1
  • cAMP binding
  • cellular response to cAMP
  • intracellular cAMP-activated cation channel activity
  • plasma membrane
  • potassium ion transmembrane transport
  • regulation of heart rate
  • regulation of monoatomic ion transmembrane transport
  • sodium channel activity
  • voltage-gated potassium channel activity
  • GO:0002027
  • GO:0005222
  • GO:0005249
  • GO:0005272
  • GO:0005886
  • GO:0030552
  • GO:0034765
  • GO:0071320
  • GO:0071805
  • ANPEP
9986
9
  • aminopeptidase activity
  • angiogenesis
  • cell differentiation
  • metallopeptidase activity
  • plasma membrane
  • proteolysis
  • zinc ion binding
  • GO:0001525
  • GO:0004177
  • GO:0005886
  • GO:0006508
  • GO:0008237
  • GO:0008270
  • GO:0030154
  • ITGA4
9986
5
  • C-X3-C chemokine binding
  • cell adhesion molecule binding
  • cell surface
  • cell-cell adhesion in response to extracellular stimulus
  • cell-cell adhesion mediated by integrin
  • cell-matrix adhesion involved in ameboidal cell migration
  • cellular response to amyloid-beta
  • endodermal cell differentiation
  • heterotypic cell-cell adhesion
  • integrin alpha4-beta7 complex
  • integrin-mediated signaling pathway
  • leukocyte tethering or rolling
  • metal ion binding
  • positive regulation of endothelial cell apoptotic process
  • positive regulation of vascular endothelial cell proliferation
  • receptor clustering
  • substrate adhesion-dependent cell spreading
  • GO:0003366
  • GO:0007229
  • GO:0009986
  • GO:0019960
  • GO:0033631
  • GO:0034113
  • GO:0034446
  • GO:0034669
  • GO:0035987
  • GO:0043113
  • GO:0046872
  • GO:0050839
  • GO:0050901
  • GO:0140039
  • GO:1904646
  • GO:1905564
  • GO:2000353
  • ADRA1D
9986
2
  • alpha1-adrenergic receptor activity
  • plasma membrane
  • GO:0004937
  • GO:0005886
  • RHCG
9986
1
  • ammonium transmembrane transport
  • ammonium transmembrane transporter activity
  • apical plasma membrane
  • carbon dioxide transmembrane transporter activity
  • cytoplasmic vesicle
  • GO:0008519
  • GO:0016324
  • GO:0031410
  • GO:0035379
  • GO:0072488
  • CD38
9986
5
  • NAD(P)+ nucleosidase activity
  • NAD+ nucleosidase activity
  • NAD+ nucleotidase, cyclic ADP-ribose generating
  • endoplasmic reticulum membrane
  • intracellular membrane-bounded organelle
  • intracellular signal transduction
  • plasma membrane
  • transferase activity
  • GO:0003953
  • GO:0005789
  • GO:0005886
  • GO:0016740
  • GO:0035556
  • GO:0043231
  • GO:0050135
  • GO:0061809
  • C5AR1
9986
1
  • G protein-coupled receptor activity
  • apical part of cell
  • basolateral plasma membrane
  • chemotaxis
  • complement component C5a receptor activity
  • cytoplasmic vesicle
  • mRNA transcription by RNA polymerase II
  • positive regulation of ERK1 and ERK2 cascade
  • positive regulation of epithelial cell proliferation
  • GO:0004878
  • GO:0004930
  • GO:0006935
  • GO:0016323
  • GO:0031410
  • GO:0042789
  • GO:0045177
  • GO:0050679
  • GO:0070374
  • FGFR2
9986
8
  • ATP binding
  • fibroblast growth factor receptor activity
  • phosphorylation
  • plasma membrane
  • positive regulation of cell population proliferation
  • GO:0005007
  • GO:0005524
  • GO:0005886
  • GO:0008284
  • GO:0016310
  • FGFR1
9986
8
  • ATP binding
  • animal organ development
  • cytoplasmic vesicle
  • cytosol
  • fibroblast growth factor receptor activity
  • nucleus
  • phosphorylation
  • plasma membrane
  • positive regulation of cell population proliferation
  • GO:0005007
  • GO:0005524
  • GO:0005634
  • GO:0005829
  • GO:0005886
  • GO:0008284
  • GO:0016310
  • GO:0031410
  • GO:0048513
  • P2RX2
9986
1
  • ATP binding
  • extracellularly ATP-gated monoatomic cation channel activity
  • plasma membrane
  • postsynapse
  • purinergic nucleotide receptor activity
  • response to ATP
  • GO:0001614
  • GO:0004931
  • GO:0005524
  • GO:0005886
  • GO:0033198
  • GO:0098794
Displaying entries 341 - 350 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01