GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Nucleosome-remodeling factor subunit BPTF	Q12830	BPTF	Homo sapiens	9606	68	ATPase complex NURF complex RNA polymerase II cis-regulatory region sequence-specific DNA binding anterior/posterior pattern specification brain development cell body cellular response to nerve growth factor stimulus chromatin chromatin remodeling cytoplasm dendrite embryonic placenta development endoderm development extracellular exosome metal ion binding methylated histone binding negative regulation of transcription by RNA polymerase II nucleoplasm nucleus perinuclear region of cytoplasm positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II sequence-specific DNA binding	GO:0000122 GO:0000785 GO:0000978 GO:0001892 GO:0005634 GO:0005654 GO:0005737 GO:0006338 GO:0006355 GO:0006357 GO:0007420 GO:0007492 GO:0009952 GO:0016589 GO:0030425 GO:0035064 GO:0043565 GO:0044297 GO:0045944 GO:0046872 GO:0048471 GO:0070062 GO:1904949 GO:1990090
Usherin	Q2QI47	Ush2A	Mus musculus	10090	68	USH2 complex animal organ morphogenesis apical plasma membrane basement membrane ciliary basal body collagen binding cytoplasm establishment of localization in cell establishment of protein localization extracellular region hair cell differentiation identical protein binding inner ear auditory receptor cell differentiation inner ear receptor cell differentiation maintenance of animal organ identity myosin binding periciliary membrane compartment photoreceptor cell maintenance photoreceptor connecting cilium photoreceptor inner segment response to stimulus sensory perception of light stimulus sensory perception of sound stereocilia ankle link stereocilia ankle link complex stereocilium bundle stereocilium membrane tissue development visual perception	GO:0001917 GO:0002141 GO:0002142 GO:0005518 GO:0005576 GO:0005604 GO:0005737 GO:0007601 GO:0007605 GO:0009887 GO:0009888 GO:0016324 GO:0017022 GO:0032391 GO:0032421 GO:0035315 GO:0036064 GO:0042491 GO:0042802 GO:0045184 GO:0045494 GO:0048496 GO:0050896 GO:0050953 GO:0051649 GO:0060113 GO:0060171 GO:1990075 GO:1990696
CD44 antigen	P16070	CD44	Homo sapiens	9606	68	Golgi apparatus T cell activation apical plasma membrane basolateral plasma membrane cartilage development cell adhesion cell migration cell projection cell surface cell-cell adhesion cell-matrix adhesion cellular response to fibroblast growth factor stimulus collagen binding cytokine-mediated signaling pathway cytosol extracellular exosome focal adhesion hyaluronan catabolic process hyaluronic acid binding inflammatory response lamellipodium membrane macrophage migration inhibitory factor receptor complex microvillus monocyte aggregation negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator plasma membrane positive regulation of ERK1 and ERK2 cascade positive regulation of heterotypic cell-cell adhesion positive regulation of monocyte aggregation positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation regulation of lamellipodium morphogenesis secretory granule membrane transmembrane signaling receptor activity wound healing, spreading of cells	GO:0004888 GO:0005518 GO:0005540 GO:0005794 GO:0005829 GO:0005886 GO:0005902 GO:0005925 GO:0006954 GO:0007155 GO:0007160 GO:0009986 GO:0016323 GO:0016324 GO:0016477 GO:0019221 GO:0030214 GO:0030667 GO:0031258 GO:0033138 GO:0034116 GO:0035692 GO:0042110 GO:0042995 GO:0043066 GO:0043154 GO:0043518 GO:0044319 GO:0044344 GO:0050731 GO:0051216 GO:0070062 GO:0070374 GO:0070487 GO:0098609 GO:1900625 GO:1902166 GO:2000392
Methylcytosine dioxygenase TET2	Q4JK59	Tet2	Mus musculus	10090	68	5-methylcytosine catabolic process 5-methylcytosine metabolic process DNA binding DNA demethylation cell cycle chromatin organization chromosome cytosine metabolic process ferrous iron binding hematopoietic stem cell homeostasis hemoglobin metabolic process hemopoiesis homeostasis of number of cells kidney development leukocyte differentiation liver morphogenesis methylcytosine dioxygenase activity myeloid cell differentiation myeloid progenitor cell differentiation nucleoplasm nucleus positive regulation of transcription by RNA polymerase II post-embryonic development protein O-linked glycosylation spleen development zinc ion binding	GO:0001822 GO:0002318 GO:0002521 GO:0003677 GO:0005634 GO:0005654 GO:0005694 GO:0006211 GO:0006325 GO:0006493 GO:0007049 GO:0008198 GO:0008270 GO:0009791 GO:0019857 GO:0019858 GO:0020027 GO:0030097 GO:0030099 GO:0045944 GO:0048536 GO:0048872 GO:0061484 GO:0070579 GO:0072576 GO:0080111
Neurogenic locus Notch protein	P07207	N	Drosophila melanogaster	7227	68	CSL-Notch-Mastermind transcription factor complex Golgi lumen Malpighian tubule tip cell differentiation Notch signaling pathway R1/R6 cell differentiation R3/R4 cell differentiation R7 cell differentiation WW domain binding actin filament organization adherens junction apical plasma membrane asymmetric cell division axon guidance border follicle cell migration calcium ion binding cell dedifferentiation cell differentiation cell fate commitment cell surface chaeta development chaeta morphogenesis chromatin binding compartment boundary maintenance compound eye development compound eye morphogenesis compound eye retinal cell programmed cell death crystal cell differentiation cytoplasm cytosol defense response to insect determination of adult lifespan dorsal appendage formation dorsal closure dorsal/ventral axis specification early endosome embryonic hemopoiesis endocytic vesicle endoplasmic reticulum endoplasmic reticulum lumen endosome epithelial cell proliferation involved in Malpighian tubule morphogenesis epithelial cell type specification, open tracheal system eye-antennal disc development eye-antennal disc morphogenesis female germ-line stem cell population maintenance follicle cell of egg chamber development follicle cell of egg chamber migration follicle cell of egg chamber stalk formation foregut morphogenesis formation of a compartment boundary germ-line stem cell population maintenance germ-line stem-cell niche homeostasis germarium-derived egg chamber formation glial cell differentiation glial cell fate determination glial cell migration hemocyte proliferation histone acetyltransferase binding imaginal disc-derived leg joint morphogenesis imaginal disc-derived leg morphogenesis imaginal disc-derived leg segmentation imaginal disc-derived male genitalia morphogenesis imaginal disc-derived wing margin morphogenesis imaginal disc-derived wing morphogenesis imaginal disc-derived wing vein specification intestinal stem cell homeostasis lamellocyte differentiation larval lymph gland hemopoiesis late endosome lateral inhibition leg disc morphogenesis long-term memory lymph gland development membrane mesoderm development morphogenesis of an epithelial fold motor neuron axon guidance muscle cell cellular homeostasis muscle cell fate determination myoblast development negative regulation of cell-cell adhesion mediated by cadherin negative regulation of compound eye photoreceptor development negative regulation of gene expression negative regulation of lamellocyte differentiation negative regulation of neurogenesis nervous system process neuroblast development neuroblast fate determination neuroblast fate specification neuroblast proliferation neuron fate determination neuron fate specification neuronal stem cell population maintenance nucleoplasm nucleus ommatidial rotation oocyte localization involved in germarium-derived egg chamber formation oogenesis peripheral nervous system development plasma membrane positive regulation of DNA-templated transcription positive regulation of G1/S transition of mitotic cell cycle positive regulation of cell population proliferation positive regulation of crystal cell differentiation positive regulation of gene expression positive regulation of neuroblast proliferation positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II protein-containing complex regulation of cardioblast cell fate specification regulation of cell differentiation regulation of filopodium assembly regulation of glycolytic process regulation of growth regulation of mitotic cell cycle regulation of neuroblast proliferation regulation of neurogenesis regulation of stem cell division response to symbiont retinal cell programmed cell death second mitotic wave involved in compound eye morphogenesis sensory organ development sensory organ precursor cell fate determination stem cell differentiation transcription coactivator activity transmembrane signaling receptor activity wing disc dorsal/ventral pattern formation wing disc pattern formation	GO:0001745 GO:0002052 GO:0002213 GO:0003682 GO:0003713 GO:0004888 GO:0005509 GO:0005634 GO:0005654 GO:0005737 GO:0005768 GO:0005769 GO:0005770 GO:0005783 GO:0005788 GO:0005796 GO:0005829 GO:0005886 GO:0005912 GO:0006110 GO:0007015 GO:0007219 GO:0007293 GO:0007297 GO:0007298 GO:0007346 GO:0007391 GO:0007400 GO:0007403 GO:0007405 GO:0007411 GO:0007422 GO:0007423 GO:0007440 GO:0007455 GO:0007474 GO:0007476 GO:0007478 GO:0007480 GO:0007498 GO:0007521 GO:0007616 GO:0008045 GO:0008284 GO:0008340 GO:0008347 GO:0008356 GO:0008407 GO:0008587 GO:0009608 GO:0009950 GO:0009986 GO:0010001 GO:0010628 GO:0010629 GO:0014018 GO:0014019 GO:0016020 GO:0016318 GO:0016324 GO:0016330 GO:0016348 GO:0016360 GO:0022416 GO:0030139 GO:0030154 GO:0030707 GO:0030713 GO:0030718 GO:0030720 GO:0032991 GO:0035035 GO:0035153 GO:0035162 GO:0035167 GO:0035171 GO:0035172 GO:0035204 GO:0035214 GO:0035222 GO:0036011 GO:0036099 GO:0036335 GO:0040008 GO:0042686 GO:0042688 GO:0042691 GO:0043525 GO:0043697 GO:0045165 GO:0045316 GO:0045466 GO:0045595 GO:0045893 GO:0045944 GO:0046331 GO:0046666 GO:0046667 GO:0046716 GO:0046843 GO:0048052 GO:0048056 GO:0048190 GO:0048477 GO:0048542 GO:0048627 GO:0048664 GO:0048665 GO:0048749 GO:0048803 GO:0048863 GO:0050699 GO:0050767 GO:0050768 GO:0050877 GO:0051489 GO:0060250 GO:0060288 GO:0060289 GO:0060571 GO:0061331 GO:0061382 GO:0097150 GO:1900087 GO:1902692 GO:1990433 GO:2000035 GO:2000048
Fibrocystin	E2RK30	PKHD1	Canis lupus familiaris	9615	67	Golgi apparatus apical plasma membrane branching morphogenesis of an epithelial tube cell-cell junction organization chromosome, centromeric region cilium endoplasmic reticulum epithelial cell morphogenesis establishment of centrosome localization establishment of mitotic spindle orientation extracellular exosome negative regulation of epithelial cell apoptotic process nucleus positive regulation of epithelial cell proliferation regulation of cell adhesion regulation of cell-cell adhesion regulation of cell-matrix adhesion regulation of cholangiocyte proliferation regulation of establishment of planar polarity spindle	GO:0000132 GO:0000775 GO:0001952 GO:0003382 GO:0005634 GO:0005783 GO:0005794 GO:0005819 GO:0005929 GO:0016324 GO:0022407 GO:0030155 GO:0045216 GO:0048754 GO:0050679 GO:0051660 GO:0070062 GO:0090175 GO:1904036 GO:1904054
Regulation of nuclear pre-mRNA domain-containing protein 2	Q5VT52	RPRD2	Homo sapiens	9606	67	RNA polymerase II C-terminal domain binding RNA polymerase II complex binding mRNA 3'-end processing nucleoplasm transcription preinitiation complex	GO:0000993 GO:0005654 GO:0031124 GO:0097550 GO:0099122
Usherin	O75445	USH2A	Homo sapiens	9606	66	USH2 complex apical plasma membrane basement membrane ciliary basal body collagen binding cytoplasm establishment of localization in cell establishment of protein localization extracellular region hair cell differentiation identical protein binding inner ear auditory receptor cell differentiation inner ear receptor cell differentiation maintenance of animal organ identity myosin binding periciliary membrane compartment photoreceptor cell maintenance photoreceptor connecting cilium photoreceptor inner segment response to stimulus sensory perception of light stimulus sensory perception of sound stereocilia ankle link stereocilia ankle link complex stereocilium bundle stereocilium membrane visual perception	GO:0001917 GO:0002141 GO:0002142 GO:0005518 GO:0005576 GO:0005604 GO:0005737 GO:0007601 GO:0007605 GO:0016324 GO:0017022 GO:0032391 GO:0032421 GO:0035315 GO:0036064 GO:0042491 GO:0042802 GO:0045184 GO:0045494 GO:0048496 GO:0050896 GO:0050953 GO:0051649 GO:0060113 GO:0060171 GO:1990075 GO:1990696
E3 SUMO-protein ligase RanBP2	P49792	RANBP2	Homo sapiens	9606	65	NLS-bearing protein import into nucleus RNA binding SUMO ligase activity SUMO ligase complex SUMO transferase activity annulate lamellae centrosome localization cytoplasm cytoplasmic periphery of the nuclear pore complex cytosol intracellular membrane-bounded organelle mRNA transport membrane metal ion binding nuclear envelope nuclear export nuclear inclusion body nuclear membrane nuclear pore nuclear pore cytoplasmic filaments nuclear pore nuclear basket nucleocytoplasmic transport nucleoplasm protein folding protein sumoylation protein-containing complex binding regulation of gluconeogenesis response to amphetamine small GTPase binding	GO:0001975 GO:0003723 GO:0005635 GO:0005642 GO:0005643 GO:0005654 GO:0005737 GO:0005829 GO:0006111 GO:0006457 GO:0006607 GO:0006913 GO:0016020 GO:0016925 GO:0019789 GO:0031267 GO:0031965 GO:0042405 GO:0043231 GO:0044614 GO:0044615 GO:0044877 GO:0046872 GO:0051028 GO:0051168 GO:0051642 GO:0061665 GO:0106068 GO:1990723
Polypeptide N-acetylgalactosaminyltransferase 5	Q7Z7M9	GALNT5	Homo sapiens	9606	65	Golgi apparatus Golgi membrane O-glycan processing carbohydrate binding glycosaminoglycan biosynthetic process metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006024 GO:0006493 GO:0016266 GO:0030246 GO:0046872