GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Fibroblast growth factor receptor	A0A8C6CRV9	FGFR1	Moschus moschiferus	68415	8	ATP binding animal organ development cytoplasmic vesicle cytosol fibroblast growth factor receptor activity nucleus phosphorylation plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005634 GO:0005829 GO:0005886 GO:0008284 GO:0016310 GO:0031410 GO:0048513
Adenine phosphoribosyltransferase	V5BQ29	TCDM_01381	Trypanosoma cruzi Dm28c	1416333		glycosyltransferase activity	GO:0016757
Glucanase	G0RVK1	cel7a	Trichoderma reesei QM6a	431241	3	cellulose binding cellulose catabolic process extracellular region hydrolase activity, hydrolyzing O-glycosyl compounds	GO:0004553 GO:0005576 GO:0030245 GO:0030248
Ras-related protein Rab-5C	P51148	RAB5C	Homo sapiens	9606	1	G protein activity GDP binding GTP binding GTPase activity azurophil granule membrane early endosome membrane endocytosis endomembrane system endosome extracellular exosome intracellular protein transport lipid droplet lysosomal membrane melanosome plasma membrane plasma membrane to endosome transport	GO:0003924 GO:0003925 GO:0005525 GO:0005765 GO:0005768 GO:0005811 GO:0005886 GO:0006886 GO:0006897 GO:0012505 GO:0019003 GO:0031901 GO:0035577 GO:0042470 GO:0048227 GO:0070062
FAS-associated death domain protein	Q13158	FADD	Homo sapiens	9606	1	CD95 death-inducing signaling complex T cell differentiation in thymus T cell homeostasis TRAIL-activated apoptotic signaling pathway activation of cysteine-type endopeptidase activity apoptotic process apoptotic signaling pathway behavioral response to cocaine caspase binding cell body cellular response to mechanical stimulus cytoplasm cytoplasmic side of plasma membrane cytosol death effector domain binding death receptor binding death-inducing signaling complex death-inducing signaling complex assembly defense response to virus extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway via death domain receptors identical protein binding innate immune response kidney development lymph node development molecular adaptor activity motor neuron apoptotic process necroptotic signaling pathway negative regulation of activation-induced cell death of T cells negative regulation of necroptotic process plasma membrane positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation positive regulation of T cell mediated cytotoxicity positive regulation of activated T cell proliferation positive regulation of adaptive immune response positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of extrinsic apoptotic signaling pathway positive regulation of innate immune response positive regulation of interleukin-8 production positive regulation of macrophage differentiation positive regulation of proteolysis positive regulation of transcription by RNA polymerase II positive regulation of tumor necrosis factor production positive regulation of type I interferon-mediated signaling pathway positive regulation of type II interferon production protease binding protein-containing complex binding receptor serine/threonine kinase binding ripoptosome spleen development thymus development tumor necrosis factor receptor binding tumor necrosis factor receptor superfamily binding	GO:0001822 GO:0001916 GO:0002020 GO:0002821 GO:0005123 GO:0005164 GO:0005737 GO:0005829 GO:0005886 GO:0006915 GO:0008625 GO:0009898 GO:0031264 GO:0031265 GO:0032729 GO:0032757 GO:0032760 GO:0032813 GO:0033077 GO:0033612 GO:0035877 GO:0036462 GO:0042104 GO:0042802 GO:0043029 GO:0043065 GO:0043123 GO:0044297 GO:0044877 GO:0045087 GO:0045089 GO:0045651 GO:0045862 GO:0045944 GO:0048148 GO:0048535 GO:0048536 GO:0048538 GO:0051607 GO:0060090 GO:0060340 GO:0060546 GO:0070236 GO:0071260 GO:0071550 GO:0089720 GO:0097049 GO:0097190 GO:0097191 GO:0097192 GO:0097202 GO:0097342 GO:0097527 GO:2000454 GO:2001238
CCR4-NOT transcription complex subunit 4	O95628	CNOT4	Homo sapiens	9606	11	CCR4-NOT complex RNA binding cytosol metal ion binding nuclear-transcribed mRNA poly(A) tail shortening nucleus protein autoubiquitination protein ubiquitination regulation of megakaryocyte differentiation ubiquitin-dependent protein catabolic process ubiquitin-protein transferase activity	GO:0000289 GO:0003723 GO:0004842 GO:0005634 GO:0005829 GO:0006511 GO:0016567 GO:0030014 GO:0045652 GO:0046872 GO:0051865
MHC class I antigen (Fragment)	G0ZMM4	HLA-C	Homo sapiens	9606	1
P2X purinoceptor (Fragment)	A0A7L2FCC6	P2rx5	Quiscalus mexicanus	64278	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
MHC class I antigen (Fragment)	C7E574	HLA-B	Homo sapiens	9606	1
Neuropeptide CCHamide-2 receptor	Q4V622	CCHa2-R	Drosophila melanogaster	7227	3	G protein-coupled receptor signaling pathway membrane neuropeptide receptor activity neuropeptide signaling pathway plasma membrane	GO:0005886 GO:0007186 GO:0007218 GO:0008188 GO:0016020