GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
DNA (cytosine-5)-methyltransferase 3A	Q9Y6K1	DNMT3A	Homo sapiens	9606		C-5 methylation of cytosine DNA (cytosine-5-)-methyltransferase activity DNA binding DNA methylation DNA methylation on cytosine DNA methylation-dependent heterochromatin formation RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding XY body catalytic complex cellular response to amino acid stimulus cellular response to bisphenol A cellular response to ethanol cellular response to hypoxia chromatin binding chromosome, centromeric region cytoplasm euchromatin genomic imprinting hepatocyte apoptotic process heterochromatin identical protein binding metal ion binding negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II neuron differentiation nuclear matrix nucleoplasm nucleus obsolete regulation of gene expression by genomic imprinting positive regulation of cellular response to hypoxia post-fertilization epigenetic regulation of gene expression protein-cysteine methyltransferase activity response to cocaine response to estradiol response to ionizing radiation response to lead ion response to toxic substance response to vitamin A response to xenobiotic stimulus spermatogenesis transcription corepressor activity unmethylated CpG binding	GO:0000122 GO:0000775 GO:0000791 GO:0000792 GO:0000978 GO:0001741 GO:0003677 GO:0003682 GO:0003714 GO:0003886 GO:0005634 GO:0005654 GO:0005737 GO:0006306 GO:0006346 GO:0006349 GO:0007283 GO:0009410 GO:0009636 GO:0010212 GO:0010288 GO:0016363 GO:0030182 GO:0032355 GO:0032776 GO:0033189 GO:0042220 GO:0042802 GO:0043045 GO:0045322 GO:0045892 GO:0046872 GO:0061629 GO:0071230 GO:0071361 GO:0071456 GO:0071514 GO:0090116 GO:0097284 GO:0106363 GO:1900039 GO:1902494 GO:1903926
Hyaluronidase	A0A7J8D8G3	HJG63_018305	Rousettus aegyptiacus	9407	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Matrix protein 2	U5XCM7	M2	Influenza A virus (A/New Hampshire/16/2012(H3N2))	1416211	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Pannexin	Q4SWL3	PANX	Tetraodon nigroviridis	99883	2	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Arylesterase-domain-containing protein	A0A1Y2H3J2	BCR41DRAFT_345516	Lobosporangium transversale	64571	1	arylesterase activity membrane	GO:0004064 GO:0016020
Rhodopsin (Fragment)	A0A8F1SZ75	Rhod	Leptodactylus avivoca	2793425	1	G protein-coupled receptor activity membrane metal ion binding photoreceptor outer segment phototransduction visual perception	GO:0001750 GO:0004930 GO:0007601 GO:0007602 GO:0016020 GO:0046872
P2X purinoceptor	A0A834F110	FQA47_002698	Oryzias melastigma	30732	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Lactadherin	Q3TDU5	Mfge8	Mus musculus	10090	3	cell adhesion	GO:0007155
Hyaluronidase	A0A3B4FU25	SPAM1	Pundamilia nyererei	303518	1	carbohydrate metabolic process hyalurononglucosaminidase activity membrane	GO:0004415 GO:0005975 GO:0016020
F-box-like/WD repeat-containing protein TBL1XR1	Q8BHJ5	Tbl1xr1	Mus musculus	10090		DNA binding adipose tissue development beta-catenin binding blastocyst hatching chromatin organization fat pad development histone binding histone deacetylase complex lipid catabolic process mitotic spindle multicellular organism growth negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II nucleoplasm nucleus positive regulation of DNA-templated transcription positive regulation of canonical Wnt signaling pathway positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process regulation of gene expression regulation of transcription by RNA polymerase II regulation of triglyceride metabolic process response to dietary excess transcription cis-regulatory region binding transcription corepressor activity transcription repressor complex white fat cell differentiation	GO:0000118 GO:0000122 GO:0000976 GO:0001835 GO:0002021 GO:0003677 GO:0003714 GO:0005634 GO:0005654 GO:0006325 GO:0006357 GO:0008013 GO:0010468 GO:0016042 GO:0017053 GO:0035264 GO:0042393 GO:0043161 GO:0045892 GO:0045893 GO:0045944 GO:0050872 GO:0060612 GO:0060613 GO:0072686 GO:0090207 GO:0090263