GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Rhodopsin	A0A3P9DIY6	RHO	Maylandia zebra	106582	2	G protein-coupled receptor activity membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0046872
Roundabout homolog 1	O55005	Robo1	Rattus norvegicus	10116	5	LRR domain binding Roundabout signaling pathway aorta development aortic valve morphogenesis axolemma axon axon guidance axon guidance receptor activity axon midline choice point recognition cell migration involved in sprouting angiogenesis cell surface cellular response to oxygen-glucose deprivation chemorepulsion involved in postnatal olfactory bulb interneuron migration coronary vasculature development cytoplasm dendrite endocardial cushion formation endoplasmic reticulum-Golgi intermediate compartment membrane heart development homophilic cell adhesion via plasma membrane adhesion molecules identical protein binding kidney development mammary duct terminal end bud growth negative regulation of cell migration negative regulation of cell population proliferation negative regulation of chemokine-mediated signaling pathway negative regulation of gene expression negative regulation of mammary gland epithelial cell proliferation negative regulation of negative chemotaxis negative regulation of synapse assembly neuron projection extension neuronal cell body olfactory bulb interneuron development oligodendrocyte development outflow tract septum morphogenesis plasma membrane positive regulation of Notch signaling pathway involved in heart induction positive regulation of Rho protein signal transduction positive regulation of axonogenesis positive regulation of gene expression positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of vascular endothelial growth factor signaling pathway pulmonary valve morphogenesis regulation of dendrite morphogenesis spinal cord development synapse organization ventricular septum development ventricular septum morphogenesis	GO:0001822 GO:0002042 GO:0003148 GO:0003180 GO:0003184 GO:0003272 GO:0003281 GO:0005737 GO:0005886 GO:0007156 GO:0007411 GO:0007507 GO:0008046 GO:0008285 GO:0009986 GO:0010628 GO:0010629 GO:0014003 GO:0016199 GO:0021510 GO:0021836 GO:0021891 GO:0030275 GO:0030336 GO:0030424 GO:0030425 GO:0030673 GO:0030949 GO:0033116 GO:0033600 GO:0035025 GO:0035385 GO:0035481 GO:0035904 GO:0042802 GO:0043025 GO:0048814 GO:0050772 GO:0050808 GO:0050925 GO:0051964 GO:0060412 GO:0060763 GO:0060976 GO:0070100 GO:0090650 GO:1900748 GO:1990138
Glial cell line-derived neurotrophic factor	Q98TU0	gdnf	Danio rerio	7955	2	MAP kinase kinase kinase activity branching involved in ureteric bud morphogenesis diencephalon development enteric nervous system development extracellular region extracellular space glial cell-derived neurotrophic factor receptor binding growth factor activity mRNA stabilization metanephros development negative regulation of neuron apoptotic process neural crest cell migration neuron projection development peripheral nervous system development peristalsis positive regulation of branching involved in ureteric bud morphogenesis positive regulation of monooxygenase activity positive regulation of transcription by RNA polymerase II positive regulation of ureteric bud formation postganglionic parasympathetic fiber development protein homodimerization activity protein-containing complex assembly receptor tyrosine kinase binding regulation of dopamine uptake involved in synaptic transmission regulation of dopaminergic neuron differentiation regulation of morphogenesis of a branching structure sympathetic nervous system development	GO:0001656 GO:0001658 GO:0001755 GO:0004709 GO:0005576 GO:0005615 GO:0007422 GO:0008083 GO:0021536 GO:0021784 GO:0030116 GO:0030432 GO:0030971 GO:0031175 GO:0032770 GO:0042803 GO:0043524 GO:0045944 GO:0048255 GO:0048484 GO:0048485 GO:0051584 GO:0060688 GO:0065003 GO:0072107 GO:0090190 GO:1904338
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	O43598	DNPH1	Homo sapiens	9606		cytosol deoxyribonucleoside 5'-monophosphate N-glycosidase activity deoxyribonucleoside monophosphate catabolic process epithelial cell differentiation extracellular exosome identical protein binding nucleoside metabolic process nucleus positive regulation of cell growth protein homodimerization activity purine nucleotide catabolic process	GO:0005634 GO:0005829 GO:0006195 GO:0009116 GO:0009159 GO:0030307 GO:0030855 GO:0042802 GO:0042803 GO:0070062 GO:0070694
Sciellin	O95171	SCEL	Homo sapiens	9606	1	cornified envelope cytoplasm embryo development ending in birth or egg hatching epidermis development extracellular exosome keratinocyte differentiation metal ion binding perinuclear region of cytoplasm positive regulation of canonical Wnt signaling pathway response to mechanical stimulus	GO:0001533 GO:0005737 GO:0008544 GO:0009612 GO:0009792 GO:0030216 GO:0046872 GO:0048471 GO:0070062 GO:0090263
Hyaluronidase	A0A6G0HQZ6	D5F01_LYC20427	Larimichthys crocea	215358	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
UDP-arabinopyranose mutase	A0A1J7I124	TanjilG_32446	Lupinus angustifolius	3871	1	Golgi apparatus UDP-L-arabinose metabolic process UDP-arabinopyranose mutase activity cell wall organization cytosol plant-type cell wall biogenesis	GO:0005794 GO:0005829 GO:0009832 GO:0033356 GO:0052691 GO:0071555
Saitohin	Q8IWL8	STH	Homo sapiens	9606		Golgi apparatus cytoplasm cytosol nucleoplasm nucleus perinuclear region of cytoplasm positive regulation of mRNA splicing, via spliceosome	GO:0005634 GO:0005654 GO:0005737 GO:0005794 GO:0005829 GO:0048026 GO:0048471
Carboxypeptidase B2	A0A087WSY5	CPB2	Homo sapiens	9606	3	fibrinolysis metallocarboxypeptidase activity proteolysis zinc ion binding	GO:0004181 GO:0006508 GO:0008270 GO:0042730
Matrix protein 2	A0A0G3XQR6	M2	Influenza A virus (A/swine/North Carolina/01063/2006(H3N2))	1658687	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036