GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs ▼
Phosphoglycerate kinase 2	P07205	PGK2	Homo sapiens	9606		ADP binding ATP binding canonical glycolysis cytosol extracellular exosome flagellated sperm motility gluconeogenesis glycolytic process nucleus phosphoglycerate kinase activity phosphorylation sperm fibrous sheath	GO:0004618 GO:0005524 GO:0005634 GO:0005829 GO:0006094 GO:0006096 GO:0016310 GO:0030317 GO:0035686 GO:0043531 GO:0061621 GO:0070062
Phosphoglycerate kinase 1	P16617	Pgk1	Rattus norvegicus	10116		ADP binding ATP binding canonical glycolysis cellular response to hypoxia cytosol epithelial cell differentiation extracellular space gluconeogenesis glycolytic process membrane raft negative regulation of angiogenesis phosphoglycerate kinase activity phosphorylation plasminogen activation protein-disulfide reductase (NAD(P)) activity	GO:0004618 GO:0005524 GO:0005615 GO:0005829 GO:0006094 GO:0006096 GO:0016310 GO:0016525 GO:0030855 GO:0031639 GO:0043531 GO:0045121 GO:0047134 GO:0061621 GO:0071456
Phosphoglycerate kinase 1	P00558	PGK1	Homo sapiens	9606	6	ADP binding ATP binding canonical glycolysis cellular response to hypoxia cytosol epithelial cell differentiation extracellular exosome extracellular space gluconeogenesis glycolytic process membrane membrane raft negative regulation of angiogenesis phosphoglycerate kinase activity phosphorylation plasminogen activation protein-disulfide reductase (NAD(P)) activity	GO:0004618 GO:0005524 GO:0005615 GO:0005829 GO:0006094 GO:0006096 GO:0016020 GO:0016310 GO:0016525 GO:0030855 GO:0031639 GO:0043531 GO:0045121 GO:0047134 GO:0061621 GO:0070062 GO:0071456
Phosphoglycerate kinase 1	P09411	Pgk1	Mus musculus	10090	1	ADP binding ATP binding canonical glycolysis cellular response to hypoxia cytoplasm cytosol epithelial cell differentiation extracellular space gluconeogenesis glycolytic process membrane raft negative regulation of angiogenesis phosphoglycerate kinase activity phosphorylation plasminogen activation protein-disulfide reductase (NAD(P)) activity	GO:0004618 GO:0005524 GO:0005615 GO:0005737 GO:0005829 GO:0006094 GO:0006096 GO:0016310 GO:0016525 GO:0030855 GO:0031639 GO:0043531 GO:0045121 GO:0047134 GO:0061621 GO:0071456
D-3-phosphoglycerate dehydrogenase	Q61753	Phgdh	Mus musculus	10090		G1 to G0 transition L-serine biosynthetic process L-serine metabolic process NAD binding gamma-aminobutyric acid metabolic process glial cell development glutamine metabolic process glycine metabolic process myelin sheath neural tube development neurogenesis neuron projection development phosphoglycerate dehydrogenase activity regulation of gene expression spinal cord development taurine metabolic process threonine metabolic process	GO:0004617 GO:0006541 GO:0006544 GO:0006563 GO:0006564 GO:0006566 GO:0009448 GO:0010468 GO:0019530 GO:0021510 GO:0021782 GO:0021915 GO:0022008 GO:0031175 GO:0043209 GO:0051287 GO:0070314
D-3-phosphoglycerate dehydrogenase	O08651	Phgdh	Rattus norvegicus	10116		G1 to G0 transition L-serine biosynthetic process L-serine metabolic process NAD binding gamma-aminobutyric acid metabolic process glial cell development glutamine metabolic process glycine metabolic process neural tube development neurogenesis neuron projection development phosphoglycerate dehydrogenase activity regulation of gene expression serine family amino acid biosynthetic process spinal cord development taurine metabolic process threonine metabolic process	GO:0004617 GO:0006541 GO:0006544 GO:0006563 GO:0006564 GO:0006566 GO:0009070 GO:0009448 GO:0010468 GO:0019530 GO:0021510 GO:0021782 GO:0021915 GO:0022008 GO:0031175 GO:0051287 GO:0070314
D-3-phosphoglycerate dehydrogenase	O43175	PHGDH	Homo sapiens	9606	3	G1 to G0 transition L-malate dehydrogenase activity L-serine biosynthetic process NAD binding brain development cytosol electron transfer activity extracellular exosome gamma-aminobutyric acid metabolic process glial cell development glutamine metabolic process glycine metabolic process neural tube development neuron projection development phosphoglycerate dehydrogenase activity regulation of gene expression spinal cord development taurine metabolic process threonine metabolic process	GO:0004617 GO:0005829 GO:0006541 GO:0006544 GO:0006564 GO:0006566 GO:0007420 GO:0009055 GO:0009448 GO:0010468 GO:0019530 GO:0021510 GO:0021782 GO:0021915 GO:0030060 GO:0031175 GO:0051287 GO:0070062 GO:0070314
6-phosphogluconate dehydrogenase, decarboxylating	Q6WAT4	6PGDH	Trypanosoma cruzi	5693		D-gluconate metabolic process NADP binding pentose-phosphate shunt phosphogluconate dehydrogenase (decarboxylating) activity	GO:0004616 GO:0006098 GO:0019521 GO:0050661
6-phosphogluconate dehydrogenase, decarboxylating	Q9DCD0	Pgd	Mus musculus	10090		D-gluconate catabolic process D-gluconate metabolic process NADP binding NADP metabolic process carbohydrate binding carboxylic acid binding cytosol pentose biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch phosphogluconate dehydrogenase (decarboxylating) activity	GO:0004616 GO:0005829 GO:0006098 GO:0006739 GO:0009051 GO:0019322 GO:0019521 GO:0030246 GO:0031406 GO:0046177 GO:0050661
6-phosphogluconate dehydrogenase, decarboxylating	P52209	PGD	Homo sapiens	9606	1	D-gluconate catabolic process NADP binding cytosol extracellular exosome nucleus pentose biosynthetic process pentose-phosphate shunt pentose-phosphate shunt, oxidative branch phosphogluconate dehydrogenase (decarboxylating) activity	GO:0004616 GO:0005634 GO:0005829 GO:0006098 GO:0009051 GO:0019322 GO:0046177 GO:0050661 GO:0070062