GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID ▲ Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • CK820_G0021644
9598
1
  • ATP binding
  • extracellularly ATP-gated monoatomic cation channel activity
  • plasma membrane
  • postsynapse
  • purinergic nucleotide receptor activity
  • response to ATP
  • GO:0001614
  • GO:0004931
  • GO:0005524
  • GO:0005886
  • GO:0033198
  • GO:0098794
  • CACNA1C
9598
1
  • T-tubule
  • calmodulin binding
  • dendrite
  • metal ion binding
  • perikaryon
  • postsynaptic density membrane
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005516
  • GO:0005891
  • GO:0030315
  • GO:0030425
  • GO:0034765
  • GO:0043204
  • GO:0046872
  • GO:0098839
  • ACP5
9598
1
  • acid phosphatase activity
  • bone morphogenesis
  • bone resorption
  • defense response to Gram-positive bacterium
  • dephosphorylation
  • ferric iron binding
  • ferrous iron binding
  • lysosome
  • negative regulation of inflammatory response
  • negative regulation of interleukin-1 beta production
  • negative regulation of interleukin-12 production
  • negative regulation of macrophage cytokine production
  • negative regulation of nitric oxide biosynthetic process
  • negative regulation of superoxide anion generation
  • negative regulation of tumor necrosis factor production
  • nitric oxide biosynthetic process
  • response to cytokine
  • response to lipopolysaccharide
  • superoxide anion generation
  • GO:0003993
  • GO:0005764
  • GO:0006809
  • GO:0008198
  • GO:0008199
  • GO:0010936
  • GO:0016311
  • GO:0032496
  • GO:0032691
  • GO:0032695
  • GO:0032720
  • GO:0032929
  • GO:0034097
  • GO:0042554
  • GO:0045019
  • GO:0045453
  • GO:0050728
  • GO:0050830
  • GO:0060349
  • GALNS
9598
2
  • N-acetylgalactosamine-6-sulfatase activity
  • lysosome
  • GO:0005764
  • GO:0043890
  • BACE2
9598
2
  • aspartic-type endopeptidase activity
  • endosome
  • membrane
  • proteolysis
  • GO:0004190
  • GO:0005768
  • GO:0006508
  • GO:0016020
  • CACNA1C
9598
1
  • T-tubule
  • calmodulin binding
  • dendrite
  • metal ion binding
  • perikaryon
  • postsynaptic density membrane
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005516
  • GO:0005891
  • GO:0030315
  • GO:0030425
  • GO:0034765
  • GO:0043204
  • GO:0046872
  • GO:0098839
  • CK820_G0031845
9598
1
  • L-ascorbic acid binding
  • copper ion binding
  • lyase activity
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
  • peptide metabolic process
  • transport vesicle membrane
  • GO:0005507
  • GO:0006518
  • GO:0016715
  • GO:0016829
  • GO:0030658
  • GO:0031418
  • PON2
9598
2
  • acyl-L-homoserine-lactone lactonohydrolase activity
  • arylesterase activity
  • extracellular region
  • membrane
  • metal ion binding
  • GO:0004064
  • GO:0005576
  • GO:0016020
  • GO:0046872
  • GO:0102007
  • CACNA1C
9598
1
  • T-tubule
  • calmodulin binding
  • dendrite
  • metal ion binding
  • perikaryon
  • postsynaptic density membrane
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005516
  • GO:0005891
  • GO:0030315
  • GO:0030425
  • GO:0034765
  • GO:0043204
  • GO:0046872
  • GO:0098839
  • PLCD1
9598
2
  • calcium ion binding
  • intracellular signal transduction
  • lipid catabolic process
  • phosphatidylinositol phospholipase C activity
  • GO:0004435
  • GO:0005509
  • GO:0016042
  • GO:0035556
Displaying entries 69061 - 69070 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01