GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels ▼	GO IDs
Cadherin-related family member 2	Q9BYE9	CDHR2	Homo sapiens	9606	24	anchoring junction apical plasma membrane brush border brush border membrane calcium ion binding cell adhesion molecule binding cell-cell adhesion cell-cell adhesion mediated by cadherin epithelial cell differentiation extracellular exosome homophilic cell adhesion via plasma membrane adhesion molecules intermicrovillar adhesion microvillus membrane negative regulation of cell growth involved in contact inhibition plasma membrane regulation of microvillus length	GO:0005509 GO:0005886 GO:0005903 GO:0007156 GO:0016324 GO:0030855 GO:0031526 GO:0031528 GO:0032532 GO:0044331 GO:0050839 GO:0060243 GO:0070062 GO:0070161 GO:0090675 GO:0098609
Potassium voltage-gated channel subfamily A member 1	P10499	Kcna1	Rattus norvegicus	10116	1	anchoring junction apical plasma membrane axon axon development axon initial segment axon terminus brain development calyx of Held cell communication by electrical coupling cell junction cell surface cellular response to magnesium ion cerebral cortex development corpus callosum development cytoplasmic vesicle cytosol delayed rectifier potassium channel activity dendrite detection of mechanical stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of touch disordered domain specific binding endoplasmic reticulum glutamatergic synapse hippocampus development juxtaparanode region of axon magnesium ion homeostasis membrane repolarization during action potential neuroblast proliferation neuromuscular process neuronal action potential neuronal cell body neuronal signal transduction optic nerve development paranode region of axon perikaryon plasma membrane postsynaptic membrane potassium channel complex potassium ion transmembrane transport presynaptic membrane protein homooligomerization protein localization regulation of membrane potential regulation of monoatomic ion transmembrane transport regulation of muscle contraction startle response synapse voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel activity voltage-gated potassium channel complex	GO:0001964 GO:0005249 GO:0005251 GO:0005783 GO:0005829 GO:0005886 GO:0006937 GO:0007405 GO:0007420 GO:0008076 GO:0008104 GO:0009986 GO:0010644 GO:0010960 GO:0016324 GO:0019228 GO:0021554 GO:0021766 GO:0021987 GO:0022038 GO:0023041 GO:0030054 GO:0030424 GO:0030425 GO:0031410 GO:0033270 GO:0034705 GO:0034765 GO:0042391 GO:0042734 GO:0043025 GO:0043194 GO:0043204 GO:0043679 GO:0044224 GO:0044305 GO:0045202 GO:0045211 GO:0050905 GO:0050966 GO:0050976 GO:0051260 GO:0061564 GO:0070161 GO:0071286 GO:0071805 GO:0086011 GO:0097718 GO:0098978 GO:0099508 GO:1905030
Potassium voltage-gated channel subfamily A member 1	P16388	Kcna1	Mus musculus	10090	1	anchoring junction apical plasma membrane axon axon development axon initial segment axon terminus brain development calyx of Held cell communication by electrical coupling cell junction cell surface cellular response to magnesium ion cerebral cortex development corpus callosum development cytoplasmic vesicle cytosol delayed rectifier potassium channel activity dendrite detection of mechanical stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of touch disordered domain specific binding endoplasmic reticulum glutamatergic synapse hippocampus development juxtaparanode region of axon magnesium ion homeostasis membrane repolarization during action potential neuroblast proliferation neuromuscular process neuronal action potential neuronal cell body neuronal signal transduction optic nerve development paranode region of axon perikaryon plasma membrane postsynaptic membrane potassium channel complex potassium ion transmembrane transport presynaptic membrane protein homooligomerization protein localization regulation of membrane potential regulation of monoatomic ion transmembrane transport regulation of muscle contraction startle response synapse voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel activity voltage-gated potassium channel complex	GO:0001964 GO:0005249 GO:0005251 GO:0005783 GO:0005829 GO:0005886 GO:0006937 GO:0007405 GO:0007420 GO:0008076 GO:0008104 GO:0009986 GO:0010644 GO:0010960 GO:0016324 GO:0019228 GO:0021554 GO:0021766 GO:0021987 GO:0022038 GO:0023041 GO:0030054 GO:0030424 GO:0030425 GO:0031410 GO:0033270 GO:0034705 GO:0034765 GO:0042391 GO:0042734 GO:0043025 GO:0043194 GO:0043204 GO:0043679 GO:0044224 GO:0044305 GO:0045202 GO:0045211 GO:0050905 GO:0050966 GO:0050976 GO:0051260 GO:0061564 GO:0070161 GO:0071286 GO:0071805 GO:0086011 GO:0097718 GO:0098978 GO:0099508 GO:1905030
Potassium voltage-gated channel subfamily A member 1	Q09470	KCNA1	Homo sapiens	9606	1	anchoring junction apical plasma membrane axon development axon initial segment axon terminus calyx of Held cell communication by electrical coupling cell junction cell surface cellular response to magnesium ion cerebral cortex development corpus callosum development cytoplasmic vesicle cytosol delayed rectifier potassium channel activity dendrite detection of mechanical stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of touch disordered domain specific binding endoplasmic reticulum glutamatergic synapse hippocampus development juxtaparanode region of axon magnesium ion homeostasis membrane repolarization during action potential neuroblast proliferation neuromuscular process neuronal action potential neuronal cell body neuronal signal transduction optic nerve development paranode region of axon perikaryon plasma membrane postsynaptic membrane potassium ion transmembrane transport presynaptic membrane protein homooligomerization protein localization regulation of membrane potential regulation of monoatomic ion transmembrane transport regulation of muscle contraction startle response synapse voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential voltage-gated potassium channel activity voltage-gated potassium channel complex	GO:0001964 GO:0005249 GO:0005251 GO:0005783 GO:0005829 GO:0005886 GO:0006937 GO:0007405 GO:0008076 GO:0008104 GO:0009986 GO:0010644 GO:0010960 GO:0016324 GO:0019228 GO:0021554 GO:0021766 GO:0021987 GO:0022038 GO:0023041 GO:0030054 GO:0030425 GO:0031410 GO:0033270 GO:0034765 GO:0042391 GO:0042734 GO:0043025 GO:0043194 GO:0043204 GO:0043679 GO:0044224 GO:0044305 GO:0045202 GO:0045211 GO:0050905 GO:0050966 GO:0050976 GO:0051260 GO:0061564 GO:0070161 GO:0071286 GO:0071805 GO:0086011 GO:0097718 GO:0098978 GO:0099508 GO:1905030
Fas-binding factor 1	Q8TES7	FBF1	Homo sapiens	9606		anchoring junction apical junction assembly centriole centrosome ciliary basal body ciliary transition fiber cilium assembly cytosol establishment of epithelial cell polarity spindle pole	GO:0000922 GO:0005813 GO:0005814 GO:0005829 GO:0036064 GO:0043297 GO:0060271 GO:0070161 GO:0090162 GO:0097539
Prolyl endopeptidase FAP	A5D7B7	FAP	Bos taurus	9913	6	anchoring junction angiogenesis apical part of cell basal part of cell cell adhesion cell surface dipeptidyl-peptidase activity endothelial cell migration extracellular space integrin binding lamellipodium membrane melanocyte apoptotic process melanocyte proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of extracellular matrix disassembly peptidase complex plasma membrane positive regulation of execution phase of apoptosis protease binding protein homodimerization activity proteolysis proteolysis involved in protein catabolic process regulation of cell cycle regulation of collagen catabolic process ruffle membrane serine-type endopeptidase activity	GO:0001525 GO:0002020 GO:0004252 GO:0005178 GO:0005615 GO:0005886 GO:0006508 GO:0007155 GO:0008239 GO:0009986 GO:0010710 GO:0010716 GO:0031258 GO:0032587 GO:0042803 GO:0043542 GO:0045177 GO:0045178 GO:0051603 GO:0051726 GO:0060244 GO:0070161 GO:0097325 GO:1900119 GO:1902362 GO:1905368
Prolyl endopeptidase FAP	P97321	Fap	Mus musculus	10090	6	anchoring junction angiogenesis apical part of cell basal part of cell cell adhesion cell surface dipeptidyl-peptidase activity endopeptidase activity endothelial cell migration extracellular space identical protein binding integrin binding lamellipodium lamellipodium membrane melanocyte apoptotic process melanocyte proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of extracellular matrix disassembly negative regulation of extracellular matrix organization peptidase activity peptidase complex plasma membrane positive regulation of execution phase of apoptosis protease binding protein homodimerization activity proteolysis proteolysis involved in protein catabolic process regulation of cell cycle regulation of collagen catabolic process ruffle membrane serine-type endopeptidase activity serine-type peptidase activity	GO:0001525 GO:0002020 GO:0004175 GO:0004252 GO:0005178 GO:0005615 GO:0005886 GO:0006508 GO:0007155 GO:0008233 GO:0008236 GO:0008239 GO:0009986 GO:0010710 GO:0010716 GO:0030027 GO:0031258 GO:0032587 GO:0042802 GO:0042803 GO:0043542 GO:0045177 GO:0045178 GO:0051603 GO:0051726 GO:0060244 GO:0070161 GO:0097325 GO:1900119 GO:1902362 GO:1903054 GO:1905368
Endosialin	Q91V98	Cd248	Mus musculus	10090	30	anatomical structure regression calcium ion binding carbohydrate binding cell migration cytoplasm endothelial cell apoptotic process external side of plasma membrane extracellular matrix binding extracellular matrix protein binding fibroblast migration fibroblast proliferation lymph node development plasma membrane positive regulation of endothelial cell apoptotic process positive regulation of fibroblast proliferation	GO:0005509 GO:0005737 GO:0005886 GO:0009897 GO:0010761 GO:0016477 GO:0030246 GO:0048144 GO:0048146 GO:0048535 GO:0050840 GO:0060033 GO:0072577 GO:1990430 GO:2000353
Endosialin	Q9HCU0	CD248	Homo sapiens	9606	34	anatomical structure regression calcium ion binding carbohydrate binding cell migration cytoplasm endothelial cell apoptotic process external side of plasma membrane extracellular exosome extracellular matrix extracellular matrix binding extracellular matrix protein binding fibroblast migration fibroblast proliferation lymph node development positive regulation of endothelial cell apoptotic process positive regulation of fibroblast proliferation	GO:0005509 GO:0005737 GO:0009897 GO:0010761 GO:0016477 GO:0030246 GO:0031012 GO:0048144 GO:0048146 GO:0048535 GO:0050840 GO:0060033 GO:0070062 GO:0072577 GO:1990430 GO:2000353
Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	E9Q668	Sema3a	Mus musculus	10090	1	anatomical structure morphogenesis semaphorin receptor binding semaphorin-plexin signaling pathway	GO:0009653 GO:0030215 GO:0071526