GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Probable serine/threonine-protein kinase ireA	Q55GJ2	ireA	Dictyostelium discoideum	44689	2	ATP binding IRE1-TRAF2-ASK1 complex IRE1-mediated unfolded protein response RNA endonuclease activity endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum organization inositol metabolic process mRNA processing protein phosphorylation protein serine kinase activity protein serine/threonine kinase activity regulation of IRE1-mediated unfolded protein response unfolded protein binding	GO:0004521 GO:0004674 GO:0005524 GO:0005783 GO:0005789 GO:0006020 GO:0006397 GO:0006468 GO:0007029 GO:0036498 GO:0051082 GO:0106310 GO:1903894 GO:1990604
Matrix protein 2	E1TW31	M2	Influenza A virus (A/California/VRDL227/2009(H1N1))	765486	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Voltage-dependent L-type calcium channel subunit alpha	A0A670XWK7	CACNA1C	Pseudonaja textilis	8673	1	T-tubule calmodulin binding dendrite metal ion binding perikaryon postsynaptic density membrane regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005516 GO:0005891 GO:0030315 GO:0030425 GO:0034765 GO:0043204 GO:0046872 GO:0098839
Fibroblast growth factor receptor	A0A0A0A9F2	N301_07097	Charadrius vociferus	50402	8	ATP binding fibroblast growth factor receptor activity phosphorylation plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005886 GO:0008284 GO:0016310
Potassium transporter 11	O64769	POT11	Arabidopsis thaliana	3702	1	membrane plasma membrane potassium ion transmembrane transporter activity potassium ion transport	GO:0005886 GO:0006813 GO:0015079 GO:0016020
Matrix protein 2	A8C7G7	M2	Influenza A virus (A/Colorado/UR06-0453/2007(H3N2))	456220	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Spectrin beta chain, non-erythrocytic 4	Q9H254	SPTBN4	Homo sapiens	9606	1	PML body actin binding actin cytoskeleton organization actin filament actin filament binding actin filament capping adult walking behavior ankyrin binding axon hillock axon initial segment axonogenesis cardiac conduction cell body fiber cell junction cell projection central nervous system projection neuron axonogenesis clustering of voltage-gated sodium channels cortical actin cytoskeleton cytoplasm cytoskeletal protein-membrane anchor activity cytosol extracellular exosome fertilization intercalated disc juxtaparanode region of axon membrane negative regulation of heart rate neuromuscular junction development neuromuscular process neuronal cell body node of Ranvier nuclear matrix paranode region of axon phosphatase binding phospholipid binding plasma membrane positive regulation of multicellular organism growth protein localization to plasma membrane protein-containing complex assembly regulation of peptidyl-serine phosphorylation regulation of sodium ion transport sensory perception of sound spectrin spectrin binding structural constituent of cytoskeleton transmission of nerve impulse vesicle-mediated transport	GO:0002028 GO:0003779 GO:0005200 GO:0005543 GO:0005737 GO:0005829 GO:0005884 GO:0005886 GO:0007409 GO:0007528 GO:0007605 GO:0007628 GO:0008091 GO:0009566 GO:0010459 GO:0014704 GO:0016020 GO:0016192 GO:0016363 GO:0016605 GO:0019226 GO:0019902 GO:0021952 GO:0030036 GO:0030054 GO:0030506 GO:0030507 GO:0030864 GO:0033135 GO:0033268 GO:0033270 GO:0040018 GO:0042995 GO:0043025 GO:0043194 GO:0043203 GO:0044224 GO:0045162 GO:0050905 GO:0051015 GO:0051693 GO:0061337 GO:0065003 GO:0070062 GO:0070852 GO:0072659 GO:0106006
Death domain-associated protein 6	Q9UER7	DAXX	Homo sapiens	9606	3	JNK cascade PML body RNA polymerase II-specific DNA-binding transcription factor binding androgen receptor signaling pathway cellular response to cadmium ion cellular response to copper ion cellular response to diamide cellular response to heat cellular response to sodium arsenite cellular response to unfolded protein chromatin remodeling chromosome, centromeric region cytosol enzyme binding extrinsic apoptotic signaling pathway via death domain receptors heat shock protein binding histone binding molecular condensate scaffold activity negative regulation of DNA-templated transcription negative regulation of gene expression neuron intrinsic apoptotic signaling pathway in response to oxidative stress nuclear androgen receptor binding nuclear body nucleolus nucleoplasm nucleosome assembly nucleus p53 binding positive regulation of protein kinase activity positive regulation of protein phosphorylation protein homodimerization activity protein kinase activator activity protein kinase binding regulation of DNA-templated transcription regulation of apoptotic process regulation of gene expression regulation of protein ubiquitination sumo-dependent protein binding transcription coactivator activity transcription corepressor activity transcription regulator inhibitor activity ubiquitin protein ligase binding	GO:0000775 GO:0001934 GO:0002039 GO:0003713 GO:0003714 GO:0005634 GO:0005654 GO:0005730 GO:0005829 GO:0006334 GO:0006338 GO:0006355 GO:0007254 GO:0008625 GO:0010468 GO:0010629 GO:0016604 GO:0016605 GO:0019899 GO:0019901 GO:0030295 GO:0030521 GO:0031072 GO:0031396 GO:0031625 GO:0034605 GO:0034620 GO:0036480 GO:0042393 GO:0042803 GO:0042981 GO:0045860 GO:0045892 GO:0050681 GO:0061629 GO:0071276 GO:0071280 GO:0072738 GO:0140037 GO:0140416 GO:0140693 GO:1903936
Matrix protein 2	A0A1P8L7V8	M2	Influenza A virus (A/Minnesota/82/2016(H3N2))	1936906	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Polyprotein p42	P12446	M	Influenza C virus (C/JJ/1950)	11560	2	host cell endoplasmic reticulum membrane host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization structural constituent of virion viral capsid virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0016020 GO:0019028 GO:0020002 GO:0039660 GO:0039707 GO:0044167 GO:0051259 GO:0055036