GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID ▲	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Potassium two pore domain channel subfamily K member 16	K7FCN3	KCNK16	Pelodiscus sinensis	13735	1	membrane potassium channel activity	GO:0005267 GO:0016020
Pannexin	K7FDB5	PANX	Pelodiscus sinensis	13735	1	actin filament binding bleb calcium channel activity endoplasmic reticulum gap junction leak channel activity plasma membrane positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of macrophage cytokine production response to ATP response to ischemia signaling receptor binding	GO:0002931 GO:0005102 GO:0005262 GO:0005783 GO:0005886 GO:0005921 GO:0022840 GO:0032059 GO:0032730 GO:0032731 GO:0033198 GO:0051015 GO:0060907
Proto-oncogene tyrosine-protein kinase receptor Ret	K7FDV5	RET	Pelodiscus sinensis	13735	1	ATP binding calcium ion binding cellular response to retinoic acid endosome membrane glial cell-derived neurotrophic factor receptor signaling pathway homophilic cell adhesion via plasma membrane adhesion molecules membrane protein proteolysis membrane raft neuron cell-cell adhesion phosphorylation plasma membrane protein complex positive regulation of MAPK cascade positive regulation of cell adhesion mediated by integrin positive regulation of cell migration positive regulation of neuron projection development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction receptor complex transmembrane receptor protein tyrosine kinase activity	GO:0004714 GO:0005509 GO:0005524 GO:0007156 GO:0007158 GO:0010008 GO:0010976 GO:0016310 GO:0030335 GO:0033619 GO:0033630 GO:0035860 GO:0043235 GO:0043410 GO:0045121 GO:0051897 GO:0071300 GO:0098797
Fibroblast growth factor receptor	K7FGA2	FGFR1	Pelodiscus sinensis	13735	8	ATP binding epithelial to mesenchymal transition fibroblast growth factor binding fibroblast growth factor receptor activity heparin binding phosphorylation plasma membrane positive regulation of MAPK cascade positive regulation of blood vessel endothelial cell migration positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of neuron differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of vascular endothelial cell proliferation protein homodimerization activity receptor complex receptor-receptor interaction	GO:0001837 GO:0005007 GO:0005524 GO:0005886 GO:0008201 GO:0016310 GO:0017134 GO:0042803 GO:0043235 GO:0043410 GO:0043536 GO:0045666 GO:0051897 GO:0090722 GO:1905564 GO:2000546
Phosphoinositide phospholipase C	K7FGT9	PLCD1	Pelodiscus sinensis	13735	2	GTPase activating protein binding calcium ion binding cytoplasm intracellular signal transduction lipid catabolic process phosphatidylinositol metabolic process phosphatidylinositol phospholipase C activity phosphatidylinositol-4,5-bisphosphate binding	GO:0004435 GO:0005509 GO:0005546 GO:0005737 GO:0016042 GO:0032794 GO:0035556 GO:0046488
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	K7FKS4	B3GAT1	Pelodiscus sinensis	13735	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Rhodopsin	K7FL46	RHO	Pelodiscus sinensis	13735	2	G protein-coupled receptor activity Golgi apparatus adaptation of rhodopsin mediated signaling cell-cell junction detection of temperature stimulus involved in thermoception gene expression light absorption metal ion binding photoreceptor activity photoreceptor cell maintenance photoreceptor disc membrane photoreceptor inner segment membrane photoreceptor outer segment membrane rod bipolar cell differentiation rod photoreceptor outer segment sperm head plasma membrane sperm midpiece thermotaxis visual perception	GO:0004930 GO:0005794 GO:0005911 GO:0007601 GO:0009881 GO:0010467 GO:0016037 GO:0016062 GO:0042622 GO:0043052 GO:0045494 GO:0046872 GO:0050960 GO:0060342 GO:0097225 GO:0097381 GO:0120200 GO:1904389 GO:1990913
Fibroblast growth factor receptor	K7FL51	FGFR2	Pelodiscus sinensis	13735	8	ATP binding fibroblast growth factor receptor activity phosphorylation plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005886 GO:0008284 GO:0016310
Fibroblast growth factor receptor	K7FL60	FGFR2	Pelodiscus sinensis	13735	8	ATP binding cell cortex cell surface collagen-containing extracellular matrix embryonic cranial skeleton morphogenesis fibroblast growth factor binding fibroblast growth factor receptor activity negative regulation of keratinocyte proliferation nucleus phosphorylation plasma membrane positive regulation of MAPK cascade positive regulation of cell population proliferation protein homodimerization activity	GO:0005007 GO:0005524 GO:0005634 GO:0005886 GO:0005938 GO:0008284 GO:0009986 GO:0010839 GO:0016310 GO:0017134 GO:0042803 GO:0043410 GO:0048701 GO:0062023
Potassium channel subfamily K member	K7FS57	KCNK1	Pelodiscus sinensis	13735	1	dendrite identical protein binding inward rectifier potassium channel activity inward rectifier potassium channel complex perikaryon potassium ion leak channel activity recycling endosome regulation of resting membrane potential sodium channel activity synaptic membrane	GO:0005242 GO:0005272 GO:0022841 GO:0030425 GO:0042802 GO:0043204 GO:0055037 GO:0060075 GO:0097060 GO:1902937