GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels ▼	GO IDs
FRAS1-related extracellular matrix protein 2	Q5SZK8	FREM2	Homo sapiens	9606	7	anatomical structure morphogenesis basement membrane cell adhesion cell communication collagen-containing extracellular matrix embryonic digit morphogenesis extracellular exosome eye development heart development inner ear development kidney development metal ion binding morphogenesis of an epithelium plasma membrane	GO:0001654 GO:0001822 GO:0002009 GO:0005604 GO:0005886 GO:0007154 GO:0007155 GO:0007507 GO:0009653 GO:0042733 GO:0046872 GO:0048839 GO:0062023 GO:0070062
FRAS1-related extracellular matrix protein 1	Q684R7	Frem1	Mus musculus	10090	6	anatomical structure morphogenesis basement membrane carbohydrate binding cell communication cell-matrix adhesion collagen-containing extracellular matrix craniofacial suture morphogenesis extracellular region membrane metal ion binding	GO:0005576 GO:0005604 GO:0007154 GO:0007160 GO:0009653 GO:0016020 GO:0030246 GO:0046872 GO:0062023 GO:0097094
FRAS1-related extracellular matrix protein 1	Q5H8C1	FREM1	Homo sapiens	9606	6	anatomical structure morphogenesis basement membrane carbohydrate binding cell communication cell-matrix adhesion collagen-containing extracellular matrix craniofacial suture morphogenesis extracellular region membrane metal ion binding	GO:0005576 GO:0005604 GO:0007154 GO:0007160 GO:0009653 GO:0016020 GO:0030246 GO:0046872 GO:0062023 GO:0097094
Fibrillin-1	Q61554	Fbn1	Mus musculus	10090	37	anatomical structure morphogenesis basement membrane calcium ion binding camera-type eye development cell adhesion mediated by integrin cellular response to insulin-like growth factor stimulus cellular response to transforming growth factor beta stimulus collagen-containing extracellular matrix embryonic eye morphogenesis extracellular matrix extracellular matrix structural constituent extracellular region extracellular space glucose homeostasis glucose metabolic process heart development heparin binding hormone activity identical protein binding integrin binding kidney development metanephros development microfibril negative regulation of osteoclast development negative regulation of osteoclast differentiation post-embryonic eye morphogenesis protein kinase A signaling protein-containing complex binding sequestering of BMP in extracellular matrix sequestering of TGFbeta in extracellular matrix skeletal system development	GO:0001501 GO:0001527 GO:0001656 GO:0001822 GO:0005178 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0005604 GO:0005615 GO:0006006 GO:0007507 GO:0008201 GO:0009653 GO:0010737 GO:0031012 GO:0033627 GO:0035582 GO:0035583 GO:0042593 GO:0042802 GO:0043010 GO:0044877 GO:0045671 GO:0048048 GO:0048050 GO:0062023 GO:0071560 GO:1990314 GO:2001205
Fibrillin-1	P35555	FBN1	Homo sapiens	9606	48	anatomical structure morphogenesis basement membrane calcium ion binding camera-type eye development cell adhesion mediated by integrin cellular response to insulin-like growth factor stimulus cellular response to transforming growth factor beta stimulus collagen-containing extracellular matrix embryonic eye morphogenesis endoplasmic reticulum lumen extracellular matrix extracellular matrix constituent conferring elasticity extracellular matrix structural constituent extracellular region extracellular space heart development heparin binding hormone activity identical protein binding integrin binding metanephros development microfibril negative regulation of osteoclast development negative regulation of osteoclast differentiation post-embryonic eye morphogenesis protein-containing complex binding sequestering of BMP in extracellular matrix sequestering of TGFbeta in extracellular matrix skeletal system development	GO:0001501 GO:0001527 GO:0001656 GO:0005178 GO:0005179 GO:0005201 GO:0005509 GO:0005576 GO:0005604 GO:0005615 GO:0005788 GO:0007507 GO:0008201 GO:0009653 GO:0030023 GO:0031012 GO:0033627 GO:0035582 GO:0035583 GO:0042802 GO:0043010 GO:0044877 GO:0045671 GO:0048048 GO:0048050 GO:0062023 GO:0071560 GO:1990314 GO:2001205
Protocadherin-16	D4ACX8	Dchs1	Rattus norvegicus	10116	4	anatomical structure morphogenesis apical part of cell branching involved in ureteric bud morphogenesis cadherin binding calcium ion binding catenin complex cell migration cell migration involved in endocardial cushion formation cell-cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cochlea development condensed mesenchymal cell proliferation digestive tract development heart morphogenesis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules hippo signaling homophilic cell adhesion via plasma membrane adhesion molecules kidney development mitral valve formation mitral valve morphogenesis nephron development neural tube development neurogenesis ossification involved in bone maturation pattern specification process post-anal tail morphogenesis protein localization to plasma membrane	GO:0001658 GO:0001822 GO:0003007 GO:0003183 GO:0003192 GO:0003273 GO:0005509 GO:0007156 GO:0007157 GO:0007389 GO:0009653 GO:0016342 GO:0016477 GO:0021915 GO:0022008 GO:0035329 GO:0036342 GO:0043931 GO:0045177 GO:0045296 GO:0048565 GO:0072006 GO:0072137 GO:0072659 GO:0090102 GO:0098609 GO:0098742
Protocadherin-16	E9PVD3	Dchs1	Mus musculus	10090	5	anatomical structure morphogenesis apical part of cell branching involved in ureteric bud morphogenesis cadherin binding calcium ion binding catenin complex cell migration cell migration involved in endocardial cushion formation cell-cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cochlea development condensed mesenchymal cell proliferation digestive tract development establishment of planar polarity heart morphogenesis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules hippo signaling homophilic cell adhesion via plasma membrane adhesion molecules kidney development mitral valve formation mitral valve morphogenesis nephron development neural tube development neurogenesis ossification involved in bone maturation pattern specification process post-anal tail morphogenesis protein localization to plasma membrane	GO:0001658 GO:0001736 GO:0001822 GO:0003007 GO:0003183 GO:0003192 GO:0003273 GO:0005509 GO:0007156 GO:0007157 GO:0007389 GO:0009653 GO:0016342 GO:0016477 GO:0021915 GO:0022008 GO:0035329 GO:0036342 GO:0043931 GO:0045177 GO:0045296 GO:0048565 GO:0072006 GO:0072137 GO:0072659 GO:0090102 GO:0098609 GO:0098742
Fibroblast growth factor 3	P11487	FGF3	Homo sapiens	9606	1	anatomical structure morphogenesis animal organ morphogenesis cell differentiation cell-cell signaling cytoplasm extracellular region extracellular space fibroblast growth factor receptor binding fibroblast growth factor receptor signaling pathway growth factor activity negative regulation of cardiac muscle tissue development positive regulation of cell division positive regulation of cell population proliferation positive regulation of gene expression positive regulation of protein phosphorylation regulation of cell migration signal transduction	GO:0001934 GO:0005104 GO:0005576 GO:0005615 GO:0005737 GO:0007165 GO:0007267 GO:0008083 GO:0008284 GO:0008543 GO:0009653 GO:0009887 GO:0010628 GO:0030154 GO:0030334 GO:0051781 GO:0055026
Cell surface glycoprotein MUC18	P43121	MCAM	Homo sapiens	9606	12	anatomical structure morphogenesis angiogenesis cell adhesion external side of plasma membrane extracellular region extracellular space focal adhesion glomerular filtration plasma membrane positive regulation of cell migration vascular wound healing	GO:0001525 GO:0003094 GO:0005576 GO:0005615 GO:0005886 GO:0005925 GO:0007155 GO:0009653 GO:0009897 GO:0030335 GO:0061042
Voltage-dependent L-type calcium channel subunit alpha	A0A8C4P0F3	CACNA1D	Dicentrarchus labrax	13489	1	anatomical structure development metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872 GO:0048856