GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID ▲	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Cathepsin D	K7G7A0	CTSD	Pelodiscus sinensis	13735	2	aspartic-type endopeptidase activity lysosome proteolysis	GO:0004190 GO:0005764 GO:0006508
Pannexin	K7G7H3	PANX3	Pelodiscus sinensis	13735	1	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Pannexin	K7G9N8	PANX	Pelodiscus sinensis	13735	1	channel activity cytoplasm gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production response to ischemia	GO:0002931 GO:0005737 GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Hyaluronidase	K7GAQ0	HYAL3	Pelodiscus sinensis	13735	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Voltage-dependent L-type calcium channel subunit alpha	K7GFC5	CACNA1S	Pelodiscus sinensis	13735	1	I band T-tubule high voltage-gated calcium channel activity metal ion binding muscle contraction regulation of monoatomic ion transmembrane transport release of sequestered calcium ion into cytosol voltage-gated calcium channel complex	GO:0005891 GO:0006936 GO:0008331 GO:0030315 GO:0031674 GO:0034765 GO:0046872 GO:0051209
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	K7GGW8	B3GAT3	Pelodiscus sinensis	13735	1	Golgi membrane chondroitin sulfate proteoglycan biosynthetic process cis-Golgi network dermatan sulfate proteoglycan biosynthetic process galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity glycosaminoglycan biosynthetic process heparan sulfate proteoglycan biosynthetic process metal ion binding positive regulation of intracellular protein transport protein phosphatase activator activity	GO:0000139 GO:0005801 GO:0006024 GO:0015012 GO:0015018 GO:0046872 GO:0050650 GO:0050651 GO:0072542 GO:0090316
P2X purinoceptor	K7GI43	P2RX1	Pelodiscus sinensis	13735	1	ATP binding ceramide biosynthetic process external side of plasma membrane extracellularly ATP-gated monoatomic cation channel activity insemination platelet activation positive regulation of monoatomic ion transport postsynaptic membrane purinergic nucleotide receptor activity regulation of calcium ion transport regulation of vascular associated smooth muscle contraction response to ATP serotonin secretion by platelet	GO:0001614 GO:0002554 GO:0003056 GO:0004931 GO:0005524 GO:0007320 GO:0009897 GO:0030168 GO:0033198 GO:0043270 GO:0045211 GO:0046513 GO:0051924
P2X purinoceptor	K7GIS9	P2RX5	Pelodiscus sinensis	13735	1	ATP binding cytosol extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005829 GO:0005886 GO:0033198 GO:0098794
Fibroblast growth factor receptor	K7GK89	FGFR2	Sus scrofa	9823	8	ATP binding fibroblast growth factor receptor activity phosphorylation plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005886 GO:0008284 GO:0016310
Fibroblast growth factor receptor	K7GQJ1	FGFR1	Sus scrofa	9823	8	ATP binding cytoplasmic vesicle cytosol epithelial to mesenchymal transition fibroblast growth factor binding fibroblast growth factor receptor activity heparin binding nucleus phosphorylation plasma membrane positive regulation of MAPK cascade positive regulation of blood vessel endothelial cell migration positive regulation of cell differentiation positive regulation of endothelial cell chemotaxis to fibroblast growth factor positive regulation of neuron differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of vascular endothelial cell proliferation protein homodimerization activity receptor complex receptor-receptor interaction transmembrane receptor protein tyrosine kinase signaling pathway	GO:0001837 GO:0005007 GO:0005524 GO:0005634 GO:0005829 GO:0005886 GO:0007169 GO:0008201 GO:0016310 GO:0017134 GO:0031410 GO:0042803 GO:0043235 GO:0043410 GO:0043536 GO:0045597 GO:0045666 GO:0051897 GO:0090722 GO:1905564 GO:2000546