GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Matrix protein 2	F0TWK6	M2	Influenza A virus (A/swine/Hong Kong/89/1979(H1N1))	991292	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
Non-structural glycoprotein 4	F5C5T0	NSP4	Rotavirus A human/Vanderbilt/VU05-06-16/2005/G1P[8]	1004839	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Leucine-rich repeat-containing protein 25	Q8K1T1	Lrrc25	Mus musculus	10090	4	cytosol endoplasmic reticulum membrane microtubule cytoskeleton	GO:0005783 GO:0005829 GO:0015630 GO:0016020
Phosphofurin acidic cluster sorting protein 1	O88588	Pacs1	Rattus norvegicus	10116		COPI-coated vesicle Golgi apparatus lymphocyte homeostasis perinuclear region of cytoplasm protein localization to Golgi apparatus protein localization to plasma membrane transmembrane transporter binding	GO:0002260 GO:0005794 GO:0030137 GO:0034067 GO:0044325 GO:0048471 GO:0072659
Activin receptor type-2B	Q95126	ACVR2B	Bos taurus	9913	2	ATP binding activin binding activin receptor activity activin receptor complex activin receptor signaling pathway cellular response to growth factor stimulus metal ion binding phosphorylation plasma membrane	GO:0005524 GO:0005886 GO:0016310 GO:0017002 GO:0032924 GO:0046872 GO:0048179 GO:0048185 GO:0071363
Peptidylglycine alpha-amidating monooxygenase	A0A8C2LX73	Pam	Cricetulus griseus	10029	1	L-ascorbic acid binding copper ion binding lyase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen peptide metabolic process transport vesicle membrane	GO:0005507 GO:0006518 GO:0016715 GO:0016829 GO:0030658 GO:0031418
NOGG protein (Fragment)	A0A7K6ZKX8	Nog	Nothoprocta pentlandii	2585814	1	cartilage development extracellular region negative regulation of BMP signaling pathway negative regulation of cell differentiation	GO:0005576 GO:0030514 GO:0045596 GO:0051216
Pannexin	A0A8C9U5K1	PANX	Scleropages formosus	113540	1	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Dedicator of cytokinesis protein 2	Q8C3J5	Dock2	Mus musculus	10090	1	GTPase activator activity T cell activation T cell proliferation T cell receptor binding actin cytoskeleton organization alpha-beta T cell activation alpha-beta T cell proliferation cell migration chemotaxis cytoplasm cytoskeleton cytoskeleton organization endomembrane system establishment of T cell polarity guanyl-nucleotide exchange factor activity immunological synapse formation macropinocytosis membrane raft polarization myeloid dendritic cell activation involved in immune response myoblast fusion negative thymic T cell selection plasma membrane positive regulation of Rac protein signal transduction positive regulation of phagocytosis positive thymic T cell selection small GTPase binding small GTPase mediated signal transduction	GO:0001766 GO:0001768 GO:0001771 GO:0002277 GO:0005085 GO:0005096 GO:0005737 GO:0005856 GO:0005886 GO:0006935 GO:0007010 GO:0007264 GO:0007520 GO:0012505 GO:0016477 GO:0030036 GO:0031267 GO:0035022 GO:0042098 GO:0042110 GO:0042608 GO:0044351 GO:0045059 GO:0045060 GO:0046631 GO:0046633 GO:0050766
Matrix protein 2	A0A2D3QT73	M2	Influenza A virus (A/Canberra/8/2015(H3N2))	2043774	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036