GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels ▼	GO IDs
Cell division cycle protein 27 homolog	P30260	CDC27	Homo sapiens	9606	3	anaphase-promoting complex anaphase-promoting complex-dependent catabolic process cell division centrosome cytoplasm cytosol metaphase/anaphase transition of mitotic cell cycle mitotic spindle nucleoplasm nucleus protein K11-linked ubiquitination protein phosphatase binding protein ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle spindle	GO:0005634 GO:0005654 GO:0005680 GO:0005737 GO:0005813 GO:0005819 GO:0005829 GO:0007091 GO:0007346 GO:0016567 GO:0019903 GO:0031145 GO:0051301 GO:0051445 GO:0070979 GO:0072686
Anaphase-promoting complex subunit 10	Q9UM13	ANAPC10	Homo sapiens	9606		anaphase-promoting complex anaphase-promoting complex-dependent catabolic process cell cycle cell division cytosol nucleoplasm protein K11-linked ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle	GO:0005654 GO:0005680 GO:0005829 GO:0007049 GO:0007346 GO:0031145 GO:0051301 GO:0051445 GO:0070979
Anaphase-promoting complex subunit CDC16	P09798	CDC16	Saccharomyces cerevisiae S288C	559292	2	anaphase-promoting complex anaphase-promoting complex-dependent catabolic process cell cycle cell division cytoplasm cytosol negative regulation of DNA-templated DNA replication initiation nucleus positive regulation of mitotic metaphase/anaphase transition protein ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle	GO:0005634 GO:0005680 GO:0005737 GO:0005829 GO:0007049 GO:0007346 GO:0016567 GO:0031145 GO:0032297 GO:0045842 GO:0051301 GO:0051445
Anaphase-promoting complex subunit 7	Q9UJX3	ANAPC7	Homo sapiens	9606		anaphase-promoting complex anaphase-promoting complex-dependent catabolic process brain development cell cycle cell division cytosol enzyme-substrate adaptor activity heterochromatin microtubule cytoskeleton nucleoplasm nucleus positive regulation of mitotic metaphase/anaphase transition protein K11-linked ubiquitination protein phosphatase binding protein ubiquitination regulation of meiotic cell cycle regulation of mitotic cell cycle spindle	GO:0000792 GO:0005634 GO:0005654 GO:0005680 GO:0005819 GO:0005829 GO:0007049 GO:0007346 GO:0007420 GO:0015630 GO:0016567 GO:0019903 GO:0031145 GO:0045842 GO:0051301 GO:0051445 GO:0070979 GO:0140767
Cell division cycle protein 20 homolog B	Q86Y33	CDC20B	Homo sapiens	9606	1	anaphase-promoting complex anaphase-promoting complex binding anaphase-promoting complex-dependent catabolic process cytoplasm de novo centriole assembly deuterosome positive regulation of anaphase-promoting complex-dependent catabolic process ubiquitin ligase activator activity	GO:0005680 GO:0005737 GO:0010997 GO:0031145 GO:0097742 GO:0098536 GO:1905786 GO:1990757
Cell division cycle protein 20 homolog	Q12834	CDC20	Homo sapiens	9606		anaphase-promoting complex anaphase-promoting complex binding anaphase-promoting complex-dependent catabolic process cell differentiation cell division centrosome cytosol kinetochore metaphase/anaphase transition of cell cycle metaphase/anaphase transition of meiosis I mitotic checkpoint complex mitotic sister chromatid cohesion mitotic spindle assembly mitotic spindle assembly checkpoint signaling nervous system development nucleoplasm positive regulation of anaphase-promoting complex-dependent catabolic process positive regulation of mitotic metaphase/anaphase transition positive regulation of synapse maturation positive regulation of synaptic plasticity positive regulation of ubiquitin protein ligase activity protein ubiquitination regulation of meiotic cell cycle regulation of meiotic nuclear division regulation of mitotic cell cycle spindle spindle pole ubiquitin ligase activator activity	GO:0000776 GO:0000922 GO:0005654 GO:0005680 GO:0005813 GO:0005819 GO:0005829 GO:0007064 GO:0007094 GO:0007346 GO:0007399 GO:0010997 GO:0016567 GO:0030154 GO:0031145 GO:0031915 GO:0033597 GO:0040020 GO:0044784 GO:0045842 GO:0051301 GO:0051445 GO:0090129 GO:0090307 GO:1904668 GO:1905786 GO:1990757 GO:1990949
Cytochrome P450 2D10	P24456	Cyp2d10	Mus musculus	10090		anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity arachidonic acid metabolic process aromatase activity cytoplasm endoplasmic reticulum membrane heme binding intracellular membrane-bounded organelle iron ion binding mitochondrion monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen xenobiotic metabolic process	GO:0004497 GO:0005506 GO:0005737 GO:0005739 GO:0005789 GO:0006805 GO:0016491 GO:0016712 GO:0019369 GO:0020037 GO:0043231 GO:0062187 GO:0062188 GO:0062189 GO:0070330
Cytochrome P450 2D9	P11714	Cyp2d9	Mus musculus	10090		anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity arachidonic acid metabolic process aromatase activity cytoplasm endoplasmic reticulum membrane heme binding intracellular membrane-bounded organelle iron ion binding mitochondrion monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen xenobiotic metabolic process	GO:0004497 GO:0005506 GO:0005737 GO:0005739 GO:0005789 GO:0006805 GO:0016491 GO:0016712 GO:0019369 GO:0020037 GO:0043231 GO:0062187 GO:0062188 GO:0062189 GO:0070330
Cytochrome P450 2D26	Q8CIM7	Cyp2d26	Mus musculus	10090		anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity anandamide 8,9 epoxidase activity arachidonic acid metabolic process aromatase activity cytoplasm endoplasmic reticulum membrane heme binding intracellular membrane-bounded organelle iron ion binding mitochondrion monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen response to xenobiotic stimulus xenobiotic metabolic process	GO:0004497 GO:0005506 GO:0005737 GO:0005739 GO:0005789 GO:0006805 GO:0009410 GO:0016491 GO:0016712 GO:0019369 GO:0020037 GO:0043231 GO:0062187 GO:0062188 GO:0062189 GO:0070330
Neprilysin	P08049	MME	Oryctolagus cuniculus	9986	5	amyloid-beta metabolic process axon bradykinin catabolic process brush border cellular response to UV-A cellular response to UV-B cellular response to cytokine stimulus creatinine metabolic process cytoplasm dendrite hormone catabolic process kidney development metalloendopeptidase activity neuron projection terminus peptide binding peptide metabolic process plasma membrane proteolysis replicative senescence sensory perception of pain substance P catabolic process synapse synaptic vesicle zinc ion binding	GO:0001822 GO:0004222 GO:0005737 GO:0005886 GO:0005903 GO:0006508 GO:0006518 GO:0008021 GO:0008270 GO:0010814 GO:0010815 GO:0019233 GO:0030424 GO:0030425 GO:0042277 GO:0042447 GO:0044306 GO:0045202 GO:0046449 GO:0050435 GO:0071345 GO:0071492 GO:0071493 GO:0090399