GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
MHC class I antigen	A0A4Y5QYY1	HLA-B	Homo sapiens	9606	1	ER to Golgi transport vesicle membrane antigen processing and presentation cell surface early endosome membrane immune response lumenal side of endoplasmic reticulum membrane phagocytic vesicle membrane plasma membrane recycling endosome membrane	GO:0005886 GO:0006955 GO:0009986 GO:0012507 GO:0019882 GO:0030670 GO:0031901 GO:0055038 GO:0098553
Xyloglucan endotransglucosylase/hydrolase	W1PT23	AMTR_s00026p00209160	Amborella trichopoda	13333	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Hyaluronidase	A0A6J0E232	LOC102921477	Peromyscus maniculatus bairdii	230844	1	carbohydrate metabolic process fusion of sperm to egg plasma membrane involved in single fertilization hyalurononglucosaminidase activity plasma membrane	GO:0004415 GO:0005886 GO:0005975 GO:0007342
Pannexin	A0A673BH41	panx2	Sphaeramia orbicularis	375764	1	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Pre-glycoprotein polyprotein GP complex	A0A2P1JNJ8	GPC	Mammarenavirus lassaense	3052310	11	fusion of virus membrane with host endosome membrane host cell Golgi membrane host cell endoplasmic reticulum membrane host cell plasma membrane membrane metal ion binding receptor-mediated endocytosis of virus by host cell viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0019065 GO:0020002 GO:0039654 GO:0044167 GO:0044178 GO:0046872 GO:0055036
Soluble MET variant 3	B5A931	MET	Homo sapiens	9606	1	membrane semaphorin receptor activity	GO:0016020 GO:0017154
Rhodopsin (Fragment)	A0A7K7F1S5	Rho_0	Chionis minor	227182	2	G protein-coupled receptor activity light absorption membrane metal ion binding photoreceptor activity phototransduction visual perception	GO:0004930 GO:0007601 GO:0007602 GO:0009881 GO:0016020 GO:0016037 GO:0046872
Xyloglucan endotransglucosylase/hydrolase	A0A4Y7JY74	C5167_009226	Papaver somniferum	3469	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Non-structural glycoprotein 4	M1GTB4	NSP4	Rotavirus A	28875	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Legumain	Q95M12	LGMN	Bos taurus	9913	4	antigen processing and presentation of exogenous peptide antigen via MHC class II cysteine-type endopeptidase activity lysosomal lumen lysosome negative regulation of ERBB signaling pathway proteolysis proteolysis involved in protein catabolic process receptor catabolic process renal system process vacuolar protein processing	GO:0003014 GO:0004197 GO:0005764 GO:0006508 GO:0006624 GO:0019886 GO:0032801 GO:0043202 GO:0051603 GO:1901185