GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Glucan 1,3-beta-glucosidase D	Q5AVZ7	exgD	Aspergillus nidulans FGSC A4	227321	7	beta-glucosidase activity cell surface cell wall organization extracellular region glucan catabolic process glucan exo-1,3-beta-glucosidase activity plasma membrane	GO:0004338 GO:0005576 GO:0005886 GO:0008422 GO:0009251 GO:0009986 GO:0071555
Solute carrier family 2, facilitated glucose transporter member 4	Q27994	SLC2A4	Bos taurus	9913	1	D-glucose transmembrane transporter activity amylopectin biosynthetic process brown fat cell differentiation cellular response to insulin stimulus cellular response to osmotic stress cellular response to tumor necrosis factor cytoplasmic vesicle membrane cytosol dehydroascorbic acid transport endomembrane system endosome external side of plasma membrane extracellular exosome glucose homeostasis glucose import glucose import in response to insulin stimulus glucose transmembrane transport glucose transmembrane transporter activity glucose uniporter activity insulin-responsive compartment membrane membrane raft perinuclear region of cytoplasm plasma membrane sarcolemma trans-Golgi network trans-Golgi network transport vesicle	GO:0005355 GO:0005768 GO:0005802 GO:0005829 GO:0005886 GO:0009897 GO:0010021 GO:0012505 GO:0015304 GO:0016020 GO:0030140 GO:0030659 GO:0032593 GO:0032869 GO:0042383 GO:0042593 GO:0044381 GO:0045121 GO:0046323 GO:0048471 GO:0050873 GO:0055056 GO:0070062 GO:0070837 GO:0071356 GO:0071470 GO:1904659
Desmoglein 2	J3KSI6	DSG2	Homo sapiens	9606	1	calcium ion binding homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane	GO:0005509 GO:0005886 GO:0007156
Voltage-dependent N-type calcium channel subunit alpha	A0A1S3NLA4	LOC106579993	Salmo salar	8030	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Potassium voltage-gated channel subfamily E member 2	P63160	Kcne2	Cavia porcellus	10141	2	apical plasma membrane negative regulation of delayed rectifier potassium channel activity plasma membrane potassium channel regulator activity voltage-gated potassium channel activity	GO:0005249 GO:0005886 GO:0015459 GO:0016324 GO:1902260
Ecto-ADP-ribosyltransferase 5	Q5XHY4	Art5	Rattus norvegicus	10116	3	NAD+ ADP-ribosyltransferase activity NAD+-protein-arginine ADP-ribosyltransferase activity extracellular region membrane nucleotidyltransferase activity	GO:0003950 GO:0005576 GO:0016020 GO:0016779 GO:0106274
Heparan-alpha-glucosaminide N-acetyltransferase	Q68CP4	HGSNAT	Homo sapiens	9606	5	acyltransferase activity heparan sulfate proteoglycan catabolic process heparan-alpha-glucosaminide N-acetyltransferase activity lysosomal lumen lysosomal membrane lysosomal transport plasma membrane protein complex oligomerization specific granule membrane tertiary granule membrane	GO:0005765 GO:0005886 GO:0007041 GO:0015019 GO:0016746 GO:0030200 GO:0035579 GO:0043202 GO:0051259 GO:0070821
P2X purinoceptor	A0A8C9SX09	p2rx4	Scleropages formosus	113540	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
Pannexin	A0A6J2D923	LOC113922777	Zalophus californianus	9704	1	gap junction helicase activity monoatomic ion transport plasma membrane	GO:0004386 GO:0005886 GO:0005921 GO:0006811
P2X purinoceptor	A0A2U9C764	SMAX5B_002450	Scophthalmus maximus	52904	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794