GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species ▲	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Envelope glycoprotein	Q6UY66	GP	Lake Victoria marburgvirus - Ozolin	482820	22	fusion of virus membrane with host endosome membrane host cell plasma membrane membrane viral entry into host cell viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0020002 GO:0039654 GO:0046718 GO:0055036
Envelope glycoprotein	P35254	GP	Lake Victoria marburgvirus - Popp	33728	22	fusion of virus membrane with host endosome membrane host cell plasma membrane membrane viral entry into host cell viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0020002 GO:0039654 GO:0046718 GO:0055036
Interleukin-12 subunit beta	Q865W9	IL12B	Lama glama	9844	2	cytokine activity cytokine receptor activity extracellular space membrane	GO:0004896 GO:0005125 GO:0005615 GO:0016020
Interleukin-12 subunit alpha	Q865X0	IL12A	Lama glama	9844	2	cytokine activity extracellular space growth factor activity immune response interleukin-12 receptor binding	GO:0005125 GO:0005143 GO:0005615 GO:0006955 GO:0008083
Tumor necrosis factor	P59694	TNF	Lama glama	9844	1	cytokine activity extracellular space immune response necroptotic signaling pathway negative regulation of protein-containing complex disassembly plasma membrane positive regulation of JUN kinase activity positive regulation of MAP kinase activity positive regulation of NF-kappaB transcription factor activity positive regulation of apoptotic process positive regulation of protein phosphorylation positive regulation of protein-containing complex disassembly regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion tumor necrosis factor receptor binding vascular endothelial growth factor production	GO:0001934 GO:0005125 GO:0005164 GO:0005615 GO:0005886 GO:0006955 GO:0010573 GO:0043065 GO:0043242 GO:0043243 GO:0043406 GO:0043507 GO:0050793 GO:0051046 GO:0051092 GO:0051239 GO:0065008 GO:0097527
Fibrinogen beta chain (Fragment)	P68122	FGB	Lama glama	9844	1	adaptive immune response blood coagulation extracellular region innate immune response	GO:0002250 GO:0005576 GO:0007596 GO:0045087
Interleukin-10	Q865X4	IL10	Lama glama	9844	1	cytokine activity extracellular space immune response negative regulation of B cell proliferation negative regulation of cytokine production involved in immune response negative regulation of inflammatory response negative regulation of interleukin-6 production negative regulation of membrane protein ectodomain proteolysis positive regulation of B cell apoptotic process positive regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of cytokine production response to glucocorticoid response to molecule of bacterial origin	GO:0001819 GO:0002237 GO:0002719 GO:0002904 GO:0005125 GO:0005615 GO:0006955 GO:0030889 GO:0032715 GO:0045893 GO:0050728 GO:0051045 GO:0051091 GO:0051384
Interleukin-1 alpha	Q865X7	IL1A	Lama glama	9844	2	cellular response to heat copper ion binding cytokine activity cytosol extracellular space fever generation immune response interleukin-1 receptor binding nucleus positive regulation of cell division response to copper ion	GO:0001660 GO:0005125 GO:0005149 GO:0005507 GO:0005615 GO:0005634 GO:0005829 GO:0006955 GO:0034605 GO:0046688 GO:0051781
Interferon gamma	Q865X1	IFNG	Lama glama	9844	2	cytokine activity defense response to virus extracellular space immune response positive regulation of autophagy type II interferon receptor binding	GO:0005125 GO:0005133 GO:0005615 GO:0006955 GO:0010508 GO:0051607
Interleukin-4	Q865X5	IL4	Lama glama	9844	4	B cell activation cytokine activity extracellular space growth factor activity immune response interleukin-4 receptor binding positive regulation of macroautophagy	GO:0005125 GO:0005136 GO:0005615 GO:0006955 GO:0008083 GO:0016239 GO:0042113