GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID ▲	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
MHC class I antigen (Fragment)	L0BVY2	HLA-C	Homo sapiens	9606	1
MHC class I antigen (Fragment)	L0BWX0	HLA-B	Homo sapiens	9606	1
MHC class I antigen (Fragment)	L0BXH5	HLA-C	Homo sapiens	9606	1
MHC class I antigen (Fragment)	L0BXM2	HLA-B	Homo sapiens	9606	1
MHC class I antigen (Fragment)	L0BXP3	HLA-C	Homo sapiens	9606	1
Non-structural glycoprotein 4	L0C9B4	NSP4	Rotavirus A	28875	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Hemagglutinin-neuraminidase	L0C9V8	HN	Mumps orthorubulavirus	2560602	1	exo-alpha-sialidase activity host cell plasma membrane host cell surface receptor binding plasma membrane viral entry into host cell viral envelope virion attachment to host cell virion membrane	GO:0004308 GO:0005886 GO:0019031 GO:0019062 GO:0020002 GO:0046718 GO:0046789 GO:0055036
Non-structural glycoprotein 4	L0CAR1	NSP4	Rotavirus A	28875	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Non-structural glycoprotein 4	L0CBA1	NSP4	Rotavirus A	28875	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729
Toll-like receptor 4	L0CL36	Tlr4	Mus musculus	10090	1	MyD88-dependent toll-like receptor signaling pathway cellular response to amyloid-beta cellular response to mechanical stimulus cellular response to oxidised low-density lipoprotein particle stimulus cellular response to type II interferon defense response to bacterium detection of lipopolysaccharide external side of plasma membrane identical protein binding inflammatory response lipopolysaccharide binding lipopolysaccharide immune receptor activity lipopolysaccharide receptor complex macrophage activation perinuclear region of cytoplasm phagocytic cup phagocytosis positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of cytokine production involved in inflammatory response positive regulation of inflammatory response positive regulation of interleukin-1 beta production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of matrix metallopeptidase secretion positive regulation of non-canonical NF-kappaB signal transduction positive regulation of tumor necrosis factor production protein heterodimerization activity signaling receptor binding toll-like receptor 4 signaling pathway transmembrane signaling receptor activity	GO:0001530 GO:0001875 GO:0001891 GO:0002755 GO:0004888 GO:0005102 GO:0006909 GO:0006954 GO:0009897 GO:0032497 GO:0032731 GO:0032735 GO:0032755 GO:0032757 GO:0032760 GO:0034142 GO:0042116 GO:0042742 GO:0042802 GO:0046696 GO:0046982 GO:0048471 GO:0050729 GO:0071260 GO:0071346 GO:0140052 GO:1900017 GO:1901224 GO:1903974 GO:1904466 GO:1904646 GO:2000343