GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs ▼
Heparanase	Q9Y251	HPSE	Homo sapiens	9606	7	angiogenesis involved in wound healing beta-glucuronidase activity cell-matrix adhesion establishment of endothelial barrier extracellular matrix extracellular region extracellular space heparan sulfate proteoglycan catabolic process heparanase activity heparin metabolic process intracellular membrane-bounded organelle lysosomal lumen lysosomal membrane lysosome membrane raft nucleoplasm nucleus positive regulation of blood coagulation positive regulation of hair follicle development positive regulation of osteoblast proliferation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of vascular endothelial growth factor production protein transmembrane transport proteoglycan metabolic process regulation of hair follicle development response to organic substance specific granule lumen syndecan binding vascular wound healing	GO:0004566 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005764 GO:0005765 GO:0006029 GO:0007160 GO:0010033 GO:0010575 GO:0030194 GO:0030200 GO:0030202 GO:0030305 GO:0031012 GO:0033690 GO:0035580 GO:0043202 GO:0043231 GO:0045121 GO:0045545 GO:0051797 GO:0051798 GO:0051897 GO:0060055 GO:0061028 GO:0061042 GO:0071806
Beta-glucuronidase	Q4FAT7	GUSB	Sus scrofa	9823	3	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process extracellular space glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process lysosomal lumen protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005975 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0043202
Beta-glucuronidase	O18835	GUSB	Canis lupus familiaris	9615	3	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process extracellular space glucuronoside catabolic process lysosome signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005975 GO:0019391 GO:0030246
Beta-glucuronidase	O97524	GUSB	Felis catus	9685	3	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process extracellular space glucuronoside catabolic process lysosome signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005975 GO:0019391 GO:0030246
Beta-glucuronidase	P06760	Gusb	Rattus norvegicus	10116	3	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process extracellular space glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process hydrolase activity lysosomal lumen lysosome protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005975 GO:0016787 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0043202
Beta-glucuronidase	P12265	Gusb	Mus musculus	10090	3	beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process endoplasmic reticulum extracellular space glucuronoside catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process hydrolase activity intracellular membrane-bounded organelle lysosomal lumen lysosome protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005615 GO:0005764 GO:0005783 GO:0005975 GO:0016787 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0043202 GO:0043231
Beta-glucuronidase	P08236	GUSB	Homo sapiens	9606	7	azurophil granule lumen beta-glucuronidase activity carbohydrate binding carbohydrate metabolic process chondroitin sulfate catabolic process extracellular exosome extracellular region extracellular space ficolin-1-rich granule lumen glucuronoside catabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process intracellular membrane-bounded organelle lysosomal lumen membrane protein domain specific binding signaling receptor binding	GO:0004566 GO:0005102 GO:0005576 GO:0005615 GO:0005975 GO:0006027 GO:0016020 GO:0019391 GO:0019904 GO:0030200 GO:0030207 GO:0030214 GO:0030246 GO:0035578 GO:0043202 GO:0043231 GO:0070062 GO:1904813
Beta-glucosidase 4	Q5N863	BGLU4	Oryza sativa Japonica Group	39947	1	beta-D-fucosidase activity beta-galactosidase activity beta-glucosidase activity cellulose catabolic process scopolin beta-glucosidase activity	GO:0004565 GO:0008422 GO:0030245 GO:0033907 GO:0102483
Beta-galactosidase	O81100	TBG4	Solanum lycopersicum	4081	2	beta-galactosidase activity carbohydrate metabolic process	GO:0004565 GO:0005975
Beta-galactosidase	Q70SY0	bga1	Trichoderma reesei	51453	5	beta-galactosidase activity carbohydrate metabolic process	GO:0004565 GO:0005975