GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Neurogenic locus protein delta	P10041	Delta	Drosophila melanogaster	7227	3	Notch binding Notch signaling pathway R3/R4 cell differentiation R7 cell differentiation actin filament organization antennal morphogenesis apical cortex apposition of dorsal and ventral imaginal disc-derived wing surfaces asymmetric cell division border follicle cell migration calcium ion binding cell fate specification cell surface chaeta morphogenesis compound eye photoreceptor development compound eye retinal cell programmed cell death cytoplasmic vesicle early endosome endocytic vesicle endosome follicle cell of egg chamber development follicle cell of egg chamber stalk formation germ-line stem cell population maintenance glial cell migration glycosphingolipid binding imaginal disc-derived leg morphogenesis imaginal disc-derived leg segmentation imaginal disc-derived wing margin morphogenesis imaginal disc-derived wing morphogenesis lateral inhibition membrane mesoderm development neuroblast fate determination neuron fate specification oocyte localization involved in germarium-derived egg chamber formation oogenesis peripheral nervous system development plasma membrane positive regulation of cell population proliferation positive regulation of mitotic cell cycle receptor ligand activity regulation of establishment of planar polarity second mitotic wave involved in compound eye morphogenesis sensory organ development stem cell differentiation wing disc anterior/posterior pattern formation wing disc dorsal/ventral pattern formation	GO:0001708 GO:0005112 GO:0005509 GO:0005768 GO:0005769 GO:0005886 GO:0007015 GO:0007219 GO:0007298 GO:0007400 GO:0007422 GO:0007423 GO:0007475 GO:0007476 GO:0007480 GO:0007498 GO:0008284 GO:0008347 GO:0008356 GO:0008407 GO:0008587 GO:0009986 GO:0016020 GO:0016330 GO:0030139 GO:0030707 GO:0030713 GO:0030718 GO:0030720 GO:0031410 GO:0036011 GO:0042051 GO:0043208 GO:0045179 GO:0045466 GO:0045931 GO:0046331 GO:0046667 GO:0048018 GO:0048056 GO:0048100 GO:0048190 GO:0048477 GO:0048665 GO:0048800 GO:0048863 GO:0090175
Receptor tyrosine-protein kinase erbB-4	Q15303	ERBB4	Homo sapiens	9606	11	ATP binding ERBB2-ERBB4 signaling pathway ERBB4 signaling pathway ERBB4-ERBB4 signaling pathway GABA receptor binding GABA-ergic synapse basal plasma membrane basolateral plasma membrane cardiac muscle tissue regeneration cell fate commitment cell migration cellular response to epidermal growth factor stimulus central nervous system morphogenesis cytosol embryonic pattern specification epidermal growth factor receptor activity epidermal growth factor receptor binding establishment of planar polarity involved in nephron morphogenesis extracellular region glutamatergic synapse heart development lactation mammary gland alveolus development mammary gland epithelial cell differentiation mitochondrial fragmentation involved in apoptotic process mitochondrial matrix mitochondrion negative regulation of apoptotic process negative regulation of cell population proliferation nervous system development neural crest cell migration neuregulin receptor activity neurogenesis neuromuscular junction neurotransmitter receptor localization to postsynaptic specialization membrane nucleoplasm nucleus obsolete positive regulation of phosphatidylinositol 3-kinase activity olfactory bulb interneuron differentiation peptidyl-tyrosine phosphorylation plasma membrane positive regulation of DNA-templated transcription positive regulation of ERK1 and ERK2 cascade positive regulation of cardiac muscle cell proliferation positive regulation of cell population proliferation positive regulation of protein localization to cell surface positive regulation of protein phosphorylation positive regulation of receptor signaling pathway via JAK-STAT positive regulation of tyrosine phosphorylation of STAT protein postsynaptic density membrane postsynaptic membrane presynaptic membrane protein autophosphorylation protein homodimerization activity protein tyrosine kinase activity receptor complex regulation of cell migration signal transduction synapse assembly transcription cis-regulatory region binding transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase signaling pathway	GO:0000976 GO:0001755 GO:0001934 GO:0004713 GO:0004714 GO:0005006 GO:0005154 GO:0005524 GO:0005576 GO:0005634 GO:0005654 GO:0005739 GO:0005759 GO:0005829 GO:0005886 GO:0007165 GO:0007169 GO:0007399 GO:0007416 GO:0007507 GO:0007595 GO:0008284 GO:0008285 GO:0009880 GO:0009925 GO:0016323 GO:0016477 GO:0018108 GO:0021551 GO:0021889 GO:0022008 GO:0030334 GO:0031594 GO:0038130 GO:0038131 GO:0038135 GO:0038138 GO:0042531 GO:0042734 GO:0042803 GO:0043066 GO:0043235 GO:0043552 GO:0043653 GO:0045165 GO:0045211 GO:0045893 GO:0046427 GO:0046777 GO:0050811 GO:0060045 GO:0060644 GO:0060749 GO:0061026 GO:0070374 GO:0071364 GO:0072046 GO:0098839 GO:0098978 GO:0098982 GO:0099645 GO:2000010
Matrix protein 2	Q0A0B0	M2	Influenza A virus (A/Western Australia/25/2002(H3N2))	390180	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
MHC class I antigen (Fragment)	O62900	HLA-B	Homo sapiens	9606	1
Peptidyl-glycine alpha-amidating monooxygenase isoform X9	A0A8B8SR02	PAM	Camelus ferus	419612	1	L-ascorbic acid binding copper ion binding lyase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen peptide metabolic process transport vesicle membrane	GO:0005507 GO:0006518 GO:0016715 GO:0016829 GO:0030658 GO:0031418
bZIP transcription factor 28	Q9SG86	BZIP28	Arabidopsis thaliana	3702	5	DNA binding DNA-binding transcription factor activity Golgi membrane cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum unfolded protein response membrane nuclear envelope nucleoplasm nucleus obsolete positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response perinuclear region of cytoplasm response to endoplasmic reticulum stress response to heat response to unfolded protein	GO:0000139 GO:0003677 GO:0003700 GO:0005634 GO:0005635 GO:0005654 GO:0005737 GO:0005783 GO:0005789 GO:0006986 GO:0006990 GO:0009408 GO:0016020 GO:0030968 GO:0034976 GO:0048471
ADAM metallopeptidase with thrombospondin type 1 motif 1	A0A8C5P646	Adamts1	Jaculus jaculus	51337	3	extracellular matrix extracellular matrix organization extracellular region metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0030198 GO:0031012
P2X purinoceptor	A0A8C4B4R5	LOC114799554	Denticeps clupeoides	299321	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794
MFS-type transporter calB	A0A1V6PBC8	calB	Penicillium decumbens	69771	2	plasma membrane transmembrane transporter activity	GO:0005886 GO:0022857
Matrix protein 2	V5QXI6	M2	Influenza A virus (A/swine/North Carolina/SG1463/2004(H1N1))	1425865	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036