GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Hyaluronidase	A0A6P5DSA5	HYAL3	Bos indicus	9915	1	carbohydrate metabolic process hyalurononglucosaminidase activity	GO:0004415 GO:0005975
Beta-secretase 2	A0A452GV96	BACE2	Gopherus agassizii	38772	2	aspartic-type endopeptidase activity endosome membrane proteolysis	GO:0004190 GO:0005768 GO:0006508 GO:0016020
Beta-glucosidase 26	A3BMZ5	BGLU26	Oryza sativa Japonica Group	39947	4	beta-D-fucosidase activity beta-L-arabinosidase activity beta-galactosidase activity beta-glucosidase activity beta-mannosidase activity carbohydrate metabolic process cellobiose glucosidase activity glucan exo-1,3-beta-glucosidase activity scopolin beta-glucosidase activity	GO:0004338 GO:0004565 GO:0004567 GO:0005975 GO:0008422 GO:0033907 GO:0047701 GO:0080079 GO:0102483
Rhodopsin (Fragment)	A0A7G3VAR4	RHO	Sphaenorhynchus pauloalvini	2493651	1	G protein-coupled receptor activity membrane photoreceptor outer segment phototransduction visual perception	GO:0001750 GO:0004930 GO:0007601 GO:0007602 GO:0016020
Substance-P receptor	Q5DUB1	TACR1	Meriones unguiculatus	10047	4	plasma membrane regulation of uterine smooth muscle contraction tachykinin receptor activity	GO:0004995 GO:0005886 GO:0070472
Histidine-rich glycoprotein (Fragment)	Q28640	HRG	Oryctolagus cuniculus	9986	5	cysteine-type endopeptidase inhibitor activity defense response to fungus extracellular region fibrinolysis heme binding heparan sulfate proteoglycan binding heparin binding immunoglobulin binding metal ion binding negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of cell adhesion negative regulation of cell adhesion mediated by integrin negative regulation of cell growth negative regulation of cell population proliferation negative regulation of endothelial cell chemotaxis negative regulation of lamellipodium assembly negative regulation of vascular endothelial growth factor signaling pathway platelet activation positive regulation of apoptotic process positive regulation of blood vessel remodeling positive regulation of focal adhesion assembly positive regulation of immune response to tumor cell regulation of actin cytoskeleton organization regulation of blood coagulation regulation of gene expression regulation of peptidyl-tyrosine phosphorylation regulation of plasminogen activation regulation of platelet activation regulation of protein-containing complex assembly signaling receptor binding zinc ion binding	GO:0002839 GO:0004869 GO:0005102 GO:0005576 GO:0007162 GO:0008201 GO:0008270 GO:0008285 GO:0010468 GO:0010543 GO:0010593 GO:0010755 GO:0016525 GO:0019865 GO:0020037 GO:0030168 GO:0030193 GO:0030308 GO:0032956 GO:0033629 GO:0042730 GO:0043065 GO:0043254 GO:0043395 GO:0043537 GO:0046872 GO:0050730 GO:0050832 GO:0051894 GO:1900747 GO:2000504 GO:2001027
Hemagglutinin-neuraminidase protein	R4WX14	HN	Mumps orthorubulavirus	2560602	1	exo-alpha-sialidase activity host cell plasma membrane host cell surface receptor binding plasma membrane viral entry into host cell viral envelope virion attachment to host cell virion membrane	GO:0004308 GO:0005886 GO:0019031 GO:0019062 GO:0020002 GO:0046718 GO:0046789 GO:0055036
Voltage-dependent P/Q-type calcium channel subunit alpha	A0A5F8GH46	CACNA1A	Monodelphis domestica	13616	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
Xyloglucan endotransglucosylase/hydrolase	A0A438G6N7	XTH23_17	Vitis vinifera	29760	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Matrix protein 2	A0A0N9RGL5	M2	Influenza A virus (A/Mississippi/06/2014(H3N2))	1731451	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036