GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Melanocyte-stimulating hormone receptor	Q864I3	MC1R	Leontopithecus rosalia	30588	1	adenylate cyclase-activating G protein-coupled receptor signaling pathway melanocyte-stimulating hormone receptor activity plasma membrane	GO:0004980 GO:0005886 GO:0007189
Xyloglucan endotransglucosylase/hydrolase	F6GXE0	VIT_11s0052g01280	Vitis vinifera	29760	1	apoplast cell wall biogenesis cell wall organization hydrolase activity, hydrolyzing O-glycosyl compounds xyloglucan metabolic process xyloglucan:xyloglucosyl transferase activity	GO:0004553 GO:0010411 GO:0016762 GO:0042546 GO:0048046 GO:0071555
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase	A0A6J2BXA7	B3GAT1	Zalophus californianus	9704	1	Golgi membrane galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity metal ion binding	GO:0000139 GO:0015018 GO:0046872
Clathrin heavy chain 1	Q00610	CLTC	Homo sapiens	9606	2	RNA binding amyloid-beta clearance by transcytosis autophagy cell division clathrin coat clathrin coat assembly clathrin coat of coated pit clathrin coat of trans-Golgi network vesicle clathrin complex clathrin light chain binding clathrin-coated endocytic vesicle clathrin-coated endocytic vesicle membrane clathrin-coated vesicle clathrin-dependent endocytosis cytosol disordered domain specific binding double-stranded RNA binding endolysosome membrane endosome extracellular exosome extracellular vesicle focal adhesion intracellular protein transport low-density lipoprotein particle receptor binding lysosome melanosome membrane mitotic cell cycle mitotic spindle mitotic spindle microtubule negative regulation of hyaluronan biosynthetic process negative regulation of protein localization to plasma membrane osteoblast differentiation plasma membrane protein kinase binding protein-containing complex receptor internalization receptor-mediated endocytosis regulation of mitotic spindle organization retrograde transport, endosome to Golgi spindle structural molecule activity trans-Golgi network membrane transferrin transport ubiquitin-specific protease binding	GO:0000278 GO:0001649 GO:0003723 GO:0003725 GO:0005198 GO:0005764 GO:0005768 GO:0005819 GO:0005829 GO:0005886 GO:0005925 GO:0006886 GO:0006898 GO:0006914 GO:0016020 GO:0019901 GO:0030118 GO:0030130 GO:0030132 GO:0030136 GO:0030669 GO:0031623 GO:0032051 GO:0032588 GO:0032991 GO:0033572 GO:0036020 GO:0042147 GO:0042470 GO:0045334 GO:0048268 GO:0050750 GO:0051301 GO:0060236 GO:0070062 GO:0071439 GO:0072583 GO:0072686 GO:0097718 GO:0150093 GO:1900126 GO:1903077 GO:1903561 GO:1990381 GO:1990498
Lipocalin 2	X6R8F3	LCN2	Homo sapiens	9606	1	extracellular region small molecule binding	GO:0005576 GO:0036094
Receptor like protein 24	O49329	RLP24	Arabidopsis thaliana	3702	16	plasma membrane	GO:0005886
Voltage-dependent P/Q-type calcium channel subunit alpha	A0A9D3PJ23	MATL_G00217890	Megalops atlanticus	7932	1	metal ion binding regulation of monoatomic ion transmembrane transport voltage-gated calcium channel activity voltage-gated calcium channel complex	GO:0005245 GO:0005891 GO:0034765 GO:0046872
ATS1 metalloproteinase (Fragment)	A0A852CK19	Adamts1	Ramphastos sulfuratus	322582	2	extracellular matrix extracellular matrix organization extracellular region metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0030198 GO:0031012
Cathepsin D (Fragment)	A0A7L1H1F5	Ctsd	Indicator maculatus	545262	2	aspartic-type endopeptidase activity lysosome proteolysis	GO:0004190 GO:0005764 GO:0006508
Non-structural glycoprotein 4	A5X357	NSP4	Human rotavirus A	10941	2	extracellular region host caveola host cell rough endoplasmic reticulum membrane induction by virus of host autophagy membrane metal ion binding monoatomic ion channel activity protein complex oligomerization toxin activity virus-mediated pore formation in host cell membrane	GO:0005216 GO:0005576 GO:0016020 GO:0039520 GO:0039707 GO:0044155 GO:0044169 GO:0046872 GO:0051259 GO:0090729