GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▲	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
Oncostatin M receptor	B9EHD2	Osmr	Mus musculus	10090	9	cytokine receptor activity membrane	GO:0004896 GO:0016020
Oncostatin M receptor	G3X8V6	Osmr	Mus musculus	10090	9	apical plasma membrane growth factor binding oncostatin-M receptor activity oncostatin-M receptor complex positive regulation of cell population proliferation	GO:0004924 GO:0005900 GO:0008284 GO:0016324 GO:0019838
Oncostatin-M	P53346	OSM	Bos taurus	9913	1	cytokine activity extracellular space immune response oncostatin-M receptor binding oncostatin-M-mediated signaling pathway positive regulation of metabolic process regulation of cell communication regulation of signaling	GO:0005125 GO:0005147 GO:0005615 GO:0006955 GO:0009893 GO:0010646 GO:0023051 GO:0038165
Oncostatin-M	P13725	OSM	Homo sapiens	9606	2	cytokine activity extracellular region extracellular space growth factor activity immune response negative regulation of cell population proliferation negative regulation of hormone secretion oncostatin-M receptor binding oncostatin-M-mediated signaling pathway positive regulation of MAPK cascade positive regulation of acute inflammatory response positive regulation of cell division positive regulation of cell population proliferation positive regulation of inflammatory response positive regulation of interleukin-17 production positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II positive regulation of tyrosine phosphorylation of STAT protein regulation of hematopoietic stem cell differentiation	GO:0002675 GO:0005125 GO:0005147 GO:0005576 GO:0005615 GO:0006955 GO:0008083 GO:0008284 GO:0008285 GO:0032740 GO:0033138 GO:0038165 GO:0042531 GO:0043410 GO:0045944 GO:0046888 GO:0050729 GO:0050731 GO:0051781 GO:0051897 GO:1902036
Oncostatin-M	P53347	Osm	Mus musculus	10090	3	behavioral response to pain cytokine activity extracellular space growth factor activity immune response meiotic nuclear division negative regulation of hormone secretion negative regulation of meiotic nuclear division oncostatin-M receptor binding oncostatin-M-mediated signaling pathway peripheral nervous system development positive regulation of MAPK cascade positive regulation of apoptotic signaling pathway positive regulation of cell population proliferation positive regulation of inflammatory response positive regulation of interleukin-17 production positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II positive regulation of tyrosine phosphorylation of STAT protein response to heat	GO:0005125 GO:0005147 GO:0005615 GO:0006955 GO:0007422 GO:0008083 GO:0008284 GO:0009408 GO:0032740 GO:0033138 GO:0038165 GO:0042531 GO:0043410 GO:0045835 GO:0045944 GO:0046888 GO:0048266 GO:0050729 GO:0050731 GO:0051897 GO:0140013 GO:2001235
Oncostatin-M-specific receptor subunit beta	Q99650	OSMR	Homo sapiens	9606	12	apical plasma membrane ciliary neurotrophic factor receptor binding cytokine binding cytokine receptor activity cytokine-mediated signaling pathway external side of plasma membrane growth factor binding oncostatin-M receptor complex oncostatin-M-mediated signaling pathway plasma membrane positive regulation of acute inflammatory response positive regulation of cell population proliferation receptor complex response to cytokine	GO:0002675 GO:0004896 GO:0005127 GO:0005886 GO:0005900 GO:0008284 GO:0009897 GO:0016324 GO:0019221 GO:0019838 GO:0019955 GO:0034097 GO:0038165 GO:0043235
Oncostatin-M-specific receptor subunit beta	Q65Z14	Osmr	Rattus norvegicus	10116	5	apical plasma membrane ciliary neurotrophic factor receptor binding cytokine binding cytokine receptor activity cytokine-mediated signaling pathway external side of plasma membrane growth factor binding oncostatin-M receptor activity oncostatin-M receptor complex oncostatin-M-mediated signaling pathway positive regulation of cell population proliferation receptor complex response to cytokine	GO:0004896 GO:0004924 GO:0005127 GO:0005900 GO:0008284 GO:0009897 GO:0016324 GO:0019221 GO:0019838 GO:0019955 GO:0034097 GO:0038165 GO:0043235
Oncostatin-M-specific receptor subunit beta	O70458	Osmr	Mus musculus	10090	15	apical plasma membrane cell surface receptor signaling pathway ciliary neurotrophic factor receptor binding cytokine binding cytokine receptor activity cytokine-mediated signaling pathway external side of plasma membrane growth factor binding oncostatin-M receptor activity oncostatin-M receptor complex oncostatin-M-mediated signaling pathway plasma membrane positive regulation of cell population proliferation receptor complex response to cytokine	GO:0004896 GO:0004924 GO:0005127 GO:0005886 GO:0005900 GO:0007166 GO:0008284 GO:0009897 GO:0016324 GO:0019221 GO:0019838 GO:0019955 GO:0034097 GO:0038165 GO:0043235
One cut domain family member 2	O95948	ONECUT2	Homo sapiens	9606	2	DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding actin cytoskeleton animal organ morphogenesis cell fate commitment chromatin cilium assembly endocrine pancreas development epithelial cell development liver development mesenchymal stem cell migration negative regulation of transforming growth factor beta receptor signaling pathway nucleoplasm nucleus peripheral nervous system neuron development positive regulation of mesenchymal stem cell migration positive regulation of transcription by RNA polymerase II regulation of cell-matrix adhesion regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding transforming growth factor beta receptor signaling pathway	GO:0000785 GO:0000978 GO:0000981 GO:0001228 GO:0001889 GO:0001952 GO:0002064 GO:0005634 GO:0005654 GO:0006357 GO:0007179 GO:0009887 GO:0015629 GO:0030512 GO:0031018 GO:0045165 GO:0045944 GO:0048935 GO:0060271 GO:1905319 GO:1905322 GO:1990837
Oocyte-secreted protein 3	A0A2R8YFM6	OOSP3	Homo sapiens	9606	6	extracellular region	GO:0005576