GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels ▼	GO IDs
Aminomethyltransferase	Q4CYN6	Tc00.1047053511231.50	Trypanosoma cruzi strain CL Brener	353153		aminomethyltransferase activity glycine catabolic process mitochondrion transaminase activity	GO:0004047 GO:0005739 GO:0006546 GO:0008483
Glycine cleavage system H protein, mitochondrial	P23434	GCSH	Homo sapiens	9606		aminomethyltransferase activity cytoplasm glycine catabolic process glycine cleavage complex glycine decarboxylation via glycine cleavage system mitochondrial matrix mitochondrion protein lipoylation	GO:0004047 GO:0005737 GO:0005739 GO:0005759 GO:0005960 GO:0006546 GO:0009249 GO:0019464
Glycine cleavage system H protein, mitochondrial	Q91WK5	Gcsh	Mus musculus	10090		aminomethyltransferase activity cytoplasm enzyme binding glycine cleavage complex glycine decarboxylation via glycine cleavage system mitochondrion protein lipoylation	GO:0004047 GO:0005737 GO:0005739 GO:0005960 GO:0009249 GO:0019464 GO:0019899
Glutathione hydrolase	Q4FK56	Ggt1	Mus musculus	10090	6	aminoacyltransferase activity cellular response to oxidative stress extracellular space glutathione biosynthetic process glutathione catabolic process glutathione hydrolase activity hepatoblast differentiation hepatocyte differentiation liver regeneration membrane peptide modification response to alcohol response to estradiol response to lipopolysaccharide response to tumor necrosis factor	GO:0005615 GO:0006750 GO:0006751 GO:0016020 GO:0016755 GO:0031179 GO:0032355 GO:0032496 GO:0034599 GO:0034612 GO:0036374 GO:0061017 GO:0070365 GO:0097305 GO:0097421
Glutathione hydrolase 1 proenzyme	Q60928	Ggt1	Mus musculus	10090	6	aminoacyltransferase activity cellular response to oxidative stress cysteine biosynthetic process endoplasmic reticulum extracellular space glutamate metabolic process glutathione biosynthetic process glutathione catabolic process glutathione hydrolase activity glutathione metabolic process hepatoblast differentiation hepatocyte differentiation leukotriene C4 gamma-glutamyl transferase activity leukotriene-C(4) hydrolase liver regeneration peptide modification peptidyltransferase activity perinuclear region of cytoplasm plasma membrane regulation of immune system process regulation of inflammatory response response to alcohol response to estradiol response to lipopolysaccharide response to tumor necrosis factor spermatogenesis vesicle zymogen activation	GO:0000048 GO:0002682 GO:0002951 GO:0005615 GO:0005783 GO:0005886 GO:0006536 GO:0006749 GO:0006750 GO:0006751 GO:0007283 GO:0016755 GO:0019344 GO:0031179 GO:0031638 GO:0031982 GO:0032355 GO:0032496 GO:0034599 GO:0034612 GO:0036374 GO:0048471 GO:0050727 GO:0061017 GO:0070365 GO:0097305 GO:0097421 GO:0103068
Aminoacylase, putative	Q4DGW6	Tc00.1047053506975.40	Trypanosoma cruzi strain CL Brener	353153		aminoacylase activity	GO:0004046
Eukaryotic translation elongation factor 1 epsilon-1	O43324	EEF1E1	Homo sapiens	9606	2	aminoacyl-tRNA synthetase multienzyme complex cellular response to leukemia inhibitory factor cytoplasm cytosol negative regulation of cell population proliferation nucleolus nucleoplasm nucleus positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of apoptotic process positive regulation of apoptotic signaling pathway positive regulation of cellular senescence translation	GO:0005634 GO:0005654 GO:0005730 GO:0005737 GO:0005829 GO:0006412 GO:0008285 GO:0017101 GO:0043065 GO:0043517 GO:1990830 GO:2000774 GO:2001235
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	Q8R010	Aimp2	Mus musculus	10090		aminoacyl-tRNA synthetase multienzyme complex apoptotic process cytosol molecular adaptor activity negative regulation of cell population proliferation nucleus positive regulation of neuron apoptotic process positive regulation of protein ubiquitination protein ubiquitination protein-containing complex assembly translation type II pneumocyte differentiation	GO:0005634 GO:0005829 GO:0006412 GO:0006915 GO:0008285 GO:0016567 GO:0017101 GO:0031398 GO:0043525 GO:0060090 GO:0060510 GO:0065003
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	Q13155	AIMP2	Homo sapiens	9606		aminoacyl-tRNA synthetase multienzyme complex apoptotic process cytosol membrane molecular adaptor activity negative regulation of cell population proliferation nucleus positive regulation of protein ubiquitination protein ubiquitination protein-containing complex assembly translation type II pneumocyte differentiation	GO:0005634 GO:0005829 GO:0006412 GO:0006915 GO:0008285 GO:0016020 GO:0016567 GO:0017101 GO:0031398 GO:0060090 GO:0060510 GO:0065003
Tyrosyl or methionyl-tRNA synthetase	V5BI34	TCDM_03834	Trypanosoma cruzi Dm28c	1416333		aminoacyl-tRNA ligase activity tRNA binding	GO:0000049 GO:0004812