GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • cotA
44689
  • DNA binding
  • cytoplasmic stress granule
  • glycoprotein complex
  • mRNA binding
  • spore wall
  • spore wall assembly
  • sporulation resulting in formation of a cellular spore
  • stress granule assembly
  • GO:0003677
  • GO:0003729
  • GO:0010494
  • GO:0030435
  • GO:0031160
  • GO:0034063
  • GO:0042244
  • GO:0090665
  • PGAP1
9606
4
  • GPI anchor metabolic process
  • anterior/posterior axis specification
  • attachment of GPI anchor to protein
  • embryonic pattern specification
  • endoplasmic reticulum
  • endoplasmic reticulum membrane
  • endoplasmic reticulum to Golgi vesicle-mediated transport
  • forebrain regionalization
  • hydrolase activity, acting on ester bonds
  • phosphatidylinositol deacylase activity
  • positive regulation of ER to Golgi vesicle-mediated transport
  • protein transport
  • sensory perception of sound
  • GO:0005783
  • GO:0005789
  • GO:0006505
  • GO:0006888
  • GO:0007605
  • GO:0009880
  • GO:0009948
  • GO:0015031
  • GO:0016255
  • GO:0016788
  • GO:0021871
  • GO:0050185
  • GO:1902953
  • amy1
  • amy2
510516
1
  • alpha-amylase activity
  • calcium ion binding
  • carbohydrate catabolic process
  • cell septum
  • cell wall-bounded periplasmic space
  • extracellular region
  • fungal-type cell wall
  • hyphal septin band
  • spitzenkorper
  • GO:0004556
  • GO:0005509
  • GO:0005576
  • GO:0009277
  • GO:0016052
  • GO:0030287
  • GO:0030428
  • GO:0031521
  • GO:0032163
  • L5
10515
  • adhesion receptor-mediated virion attachment to host cell
  • cell adhesion
  • host cell nucleus
  • viral capsid
  • viral entry into host cell
  • GO:0007155
  • GO:0019028
  • GO:0042025
  • GO:0046718
  • GO:0098671
  • Crim1
10090
2
  • PDZ domain binding
  • extracellular region
  • negative regulation of BMP signaling pathway
  • negative regulation of osteoblast differentiation
  • plasma membrane
  • serine-type endopeptidase inhibitor activity
  • GO:0004867
  • GO:0005576
  • GO:0005886
  • GO:0030165
  • GO:0030514
  • GO:0045668
  • Gucy1a1
10090
1
  • GABA-ergic synapse
  • GTP binding
  • cGMP biosynthetic process
  • cGMP-mediated signaling
  • glutamatergic synapse
  • guanylate cyclase activity
  • guanylate cyclase complex, soluble
  • heme binding
  • ion binding
  • nitric oxide mediated signal transduction
  • nitric oxide-cGMP-mediated signaling pathway
  • positive regulation of nitric oxide mediated signal transduction
  • protein-containing complex
  • protein-containing complex binding
  • regulation of blood pressure
  • relaxation of vascular associated smooth muscle
  • response to oxygen levels
  • retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
  • GO:0004383
  • GO:0005525
  • GO:0006182
  • GO:0007263
  • GO:0008074
  • GO:0008217
  • GO:0010750
  • GO:0019934
  • GO:0020037
  • GO:0032991
  • GO:0038060
  • GO:0043167
  • GO:0044877
  • GO:0060087
  • GO:0070482
  • GO:0098925
  • GO:0098978
  • GO:0098982
  • Ttc3
10090
1
  • Golgi apparatus
  • cytosol
  • metal ion binding
  • negative regulation of cell morphogenesis
  • negative regulation of neuron differentiation
  • nucleolus
  • nucleoplasm
  • nucleus
  • protein K48-linked ubiquitination
  • ubiquitin-dependent protein catabolic process
  • ubiquitin-protein transferase activity
  • vacuole
  • GO:0004842
  • GO:0005634
  • GO:0005654
  • GO:0005730
  • GO:0005773
  • GO:0005794
  • GO:0005829
  • GO:0006511
  • GO:0010771
  • GO:0045665
  • GO:0046872
  • GO:0070936
  • Tgoln1
10090
2
  • Golgi apparatus
  • endosome
  • nucleoplasm
  • plasma membrane
  • trans-Golgi network
  • trans-Golgi network transport vesicle
  • GO:0005654
  • GO:0005768
  • GO:0005794
  • GO:0005802
  • GO:0005886
  • GO:0030140
  • EFNA4
9606
1
  • axon guidance
  • cell-cell signaling
  • ephrin receptor binding
  • ephrin receptor signaling pathway
  • extracellular region
  • plasma membrane
  • side of membrane
  • transmembrane-ephrin receptor activity
  • GO:0005005
  • GO:0005576
  • GO:0005886
  • GO:0007267
  • GO:0007411
  • GO:0046875
  • GO:0048013
  • GO:0098552
  • Lrp3
10090
1
  • negative regulation of fat cell differentiation
  • negative regulation of gene expression
  • plasma membrane
  • positive regulation of gene expression
  • positive regulation of osteoblast differentiation
  • GO:0005886
  • GO:0010628
  • GO:0010629
  • GO:0045599
  • GO:0045669
Displaying entries 81 - 90 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01