GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▲	GO Labels	GO IDs
Protease-associated domain-containing protein 1	Q9BSG0	PRADC1	Homo sapiens	9606	1	extracellular region	GO:0005576
ATS5 metalloproteinase (Fragment)	A0A7K6TI86	Adamts5	Caloenas nicobarica	187106	1	collagen-containing extracellular matrix extracellular matrix organization extracellular region metalloendopeptidase activity proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0006508 GO:0008270 GO:0030198 GO:0062023
Bone morphogenetic protein receptor type-1B	O00238	BMPR1B	Homo sapiens	9606	1	ATP binding BMP binding BMP receptor activity BMP signaling pathway HFE-transferrin receptor complex SMAD binding cartilage condensation cellular response to BMP stimulus cellular response to growth factor stimulus central nervous system neuron differentiation chondrocyte development dendrite dorsal/ventral pattern formation endochondral bone morphogenesis eye development inflammatory response metal ion binding negative regulation of chondrocyte proliferation neuronal cell body osteoblast differentiation ovarian cumulus expansion ovulation cycle plasma membrane positive regulation of bone mineralization positive regulation of cartilage development positive regulation of chondrocyte differentiation positive regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of gene expression positive regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II protein phosphorylation protein serine/threonine kinase activity proteoglycan biosynthetic process receptor complex retina development in camera-type eye retinal ganglion cell axon guidance transforming growth factor beta receptor activity, type I transmembrane receptor protein serine/threonine kinase activity	GO:0001502 GO:0001550 GO:0001649 GO:0001654 GO:0002063 GO:0004674 GO:0004675 GO:0005025 GO:0005524 GO:0005886 GO:0006468 GO:0006954 GO:0009953 GO:0010628 GO:0021953 GO:0030166 GO:0030425 GO:0030501 GO:0030509 GO:0031290 GO:0032332 GO:0036122 GO:0042698 GO:0043025 GO:0043235 GO:0045669 GO:0045944 GO:0046332 GO:0046872 GO:0060041 GO:0060350 GO:0061036 GO:0071363 GO:0071773 GO:0098821 GO:1902043 GO:1902731 GO:1990712
MHC class I protein (Fragment)	A0A4Y5RV54	HLA-C	Homo sapiens	9606	1	membrane	GO:0016020
Hemagglutinin-neuraminidase	A0A2H4EU09	HN	Mumps virus genotype F	1384673	1	exo-alpha-sialidase activity host cell plasma membrane host cell surface receptor binding plasma membrane viral entry into host cell viral envelope virion attachment to host cell virion membrane	GO:0004308 GO:0005886 GO:0019031 GO:0019062 GO:0020002 GO:0046718 GO:0046789 GO:0055036
Amyloid-beta A4 protein	Q3TWF3	App	Mus musculus	10090	1	Golgi apparatus Golgi-associated vesicle Notch signaling pathway cell surface clathrin-coated pit early endosome endocytosis growth cone heparin binding perikaryon serine-type endopeptidase inhibitor activity transition metal ion binding	GO:0004867 GO:0005769 GO:0005794 GO:0005798 GO:0005905 GO:0006897 GO:0007219 GO:0008201 GO:0009986 GO:0030426 GO:0043204 GO:0046914
Autophagy-related protein 9 (Fragment)	C9JKV7	ATG9A	Homo sapiens	9606	1	autophagy lipid transport phagophore assembly site membrane	GO:0006869 GO:0006914 GO:0034045
Pannexin	A0A8C5NTI2	PANX	Junco hyemalis	40217	1	channel activity gap junction monoatomic cation transport plasma membrane positive regulation of interleukin-1 production	GO:0005886 GO:0005921 GO:0006812 GO:0015267 GO:0032732
Matrix protein 2	A0A1C8EBS3	M2	Influenza A virus (A/Addis Ababa/1514A07305892N/2013(H3N2))	1737150	1	host cell plasma membrane membrane monoatomic ion channel activity protein complex oligomerization proton transmembrane transporter activity suppression by virus of host autophagy virion membrane virus-mediated pore formation in host cell membrane	GO:0005216 GO:0015078 GO:0016020 GO:0020002 GO:0039521 GO:0039707 GO:0051259 GO:0055036
P2X purinoceptor	A0A671K7U8	LOC107664512	Sinocyclocheilus anshuiensis	1608454	1	ATP binding extracellularly ATP-gated monoatomic cation channel activity plasma membrane postsynapse purinergic nucleotide receptor activity response to ATP	GO:0001614 GO:0004931 GO:0005524 GO:0005886 GO:0033198 GO:0098794