GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name ▼	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites	GO Labels	GO IDs
tRNA N6-adenosine threonylcarbamoyltransferase	Q9NPF4	OSGEP	Homo sapiens	9606		EKC/KEOPS complex N(6)-L-threonylcarbamoyladenine synthase activity catalytic activity, acting on a tRNA cytoplasm cytosol metal ion binding nucleoplasm nucleus tRNA modification tRNA threonylcarbamoyladenosine modification	GO:0000408 GO:0002949 GO:0005634 GO:0005654 GO:0005737 GO:0005829 GO:0006400 GO:0046872 GO:0061711 GO:0140101
tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial	Q9H825	METTL8	Homo sapiens	9606		mRNA methylation mRNA methyltransferase activity mitochondrial tRNA modification mitochondrion positive regulation of mitochondrial translation tRNA (cytidine-3-)-methyltransferase activity tRNA C3-cytosine methylation	GO:0005739 GO:0008174 GO:0052735 GO:0070131 GO:0070900 GO:0080009 GO:0106217
tRNA N(3)-methylcytidine methyltransferase METTL2B	Q6P1Q9	METTL2B	Homo sapiens	9606		cytoplasm tRNA (cytidine) methyltransferase activity tRNA (cytidine-3-)-methyltransferase activity tRNA methylation	GO:0005737 GO:0016427 GO:0030488 GO:0052735
tRNA 2'-phosphotransferase 1	Q86TN4	TRPT1	Homo sapiens	9606		tRNA 2'-phosphotransferase activity tRNA splicing, via endonucleolytic cleavage and ligation	GO:0000215 GO:0006388
tRNA (uracil-5-)-methyltransferase homolog A	Q8IZ69	TRMT2A	Homo sapiens	9606		C-methyltransferase activity RNA binding cytosol mRNA processing tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent	GO:0003723 GO:0005829 GO:0006397 GO:0008169 GO:0030697
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	P57081	WDR4	Homo sapiens	9606		DNA damage response chromosome cytosol enzyme activator activity nucleoplasm nucleus tRNA (guanine-N7)-methylation tRNA (m7G46) methyltransferase complex tRNA methyltransferase complex tRNA modification	GO:0005634 GO:0005654 GO:0005694 GO:0005829 GO:0006400 GO:0006974 GO:0008047 GO:0043527 GO:0106004 GO:0106143
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4	Q9EP82	Wdr4	Mus musculus	10090		DNA damage response chromosome cytosol enzyme activator activity nucleoplasm nucleus tRNA (guanine-N7)-methylation tRNA (m7G46) methyltransferase complex tRNA methyltransferase complex tRNA modification	GO:0005634 GO:0005654 GO:0005694 GO:0005829 GO:0006400 GO:0006974 GO:0008047 GO:0043527 GO:0106004 GO:0106143
tRNA (guanine-N(7)-)-methyltransferase	Q9UBP6	METTL1	Homo sapiens	9606		RNA (guanine-N7)-methylation cytosol nucleolus nucleoplasm nucleus tRNA (guanine(46)-N7)-methyltransferase activity tRNA (guanine-N7)-methylation tRNA (m7G46) methyltransferase complex tRNA binding tRNA methylation tRNA methyltransferase complex tRNA modification tRNA stabilization	GO:0000049 GO:0005634 GO:0005654 GO:0005730 GO:0005829 GO:0006400 GO:0008176 GO:0030488 GO:0036265 GO:0036416 GO:0043527 GO:0106004 GO:0106143
tRNA (guanine(6)-N2)-methyltransferase THUMP3	Q9BV44	THUMPD3	Homo sapiens	9606		cytoplasm cytosol nucleolus obsolete tRNA (guanine-N2-)-methyltransferase activity tRNA (guanine) methyltransferase activity tRNA N2-guanine methylation tRNA binding tRNA methylation	GO:0000049 GO:0002940 GO:0004809 GO:0005730 GO:0005737 GO:0005829 GO:0016423 GO:0030488
tRNA (guanine(37)-N1)-methyltransferase	P38793	TRM5	Saccharomyces cerevisiae S288C	559292	4	cytoplasm mitochondrial matrix mitochondrial tRNA methylation nucleoplasm nucleus obsolete tRNA (guanine-N1-)-methyltransferase activity tRNA (guanine(37)-N1)-methyltransferase activity tRNA N1-guanine methylation tRNA modification	GO:0002939 GO:0005634 GO:0005654 GO:0005737 GO:0005759 GO:0006400 GO:0009019 GO:0052906 GO:0070901