GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect February 2, 2022
GlycoProtDB October 1, 2021
GlyGen February 2, 2022
Human Protein Atlas September 5, 2019 (Protein Atlas version 19)
MCAW-DB July 10, 2019
Reactome October 28, 2022 (Version 82)
UniProt September 8, 2022
Protein Name UniProt ID Gene Symbol Alias Symbols Species Taxonomy ID No. of Glycosylation Sites ▲ No. of GlyTouCan IDs MCAW IDs Disease Name Disease Aliases GO Labels GO IDs
FCMR
  • FAIM3
  • TOSO
Homo sapiens
9606
0
1
  • cellular defense response
  • extracellular region
  • immune system process
  • integral component of membrane
  • negative regulation of apoptotic process
  • plasma membrane
  • transmembrane signaling receptor activity
  • GO_0002376
  • GO_0004888
  • GO_0005576
  • GO_0005886
  • GO_0006968
  • GO_0016021
  • GO_0043066
SLC26A9
Homo sapiens
9606
0
1
  • ATPase binding
  • anion transport
  • anion:anion antiporter activity
  • apical plasma membrane
  • bicarbonate transmembrane transporter activity
  • bicarbonate transport
  • cell surface
  • chloride channel activity
  • chloride transmembrane transporter activity
  • chloride transport
  • extracellular exosome
  • integral component of plasma membrane
  • ion transport
  • oxalate transmembrane transporter activity
  • plasma membrane
  • positive regulation of gene expression
  • secondary active sulfate transmembrane transporter activity
  • sulfate transmembrane transporter activity
  • GO_0005254
  • GO_0005886
  • GO_0005887
  • GO_0006811
  • GO_0006820
  • GO_0006821
  • GO_0008271
  • GO_0009986
  • GO_0010628
  • GO_0015106
  • GO_0015108
  • GO_0015116
  • GO_0015301
  • GO_0015701
  • GO_0016324
  • GO_0019531
  • GO_0051117
  • GO_0070062
ZYX
Homo sapiens
9606
0
3
  • RNA binding
  • actin cytoskeleton
  • adherens junction
  • cell-cell signaling
  • cell-matrix adhesion
  • cellular response to interferon-gamma
  • cytoplasm
  • cytosol
  • focal adhesion
  • integrin-mediated signaling pathway
  • metal ion binding
  • nucleus
  • phagocytic vesicle
  • plasma membrane
  • regulation of inflammatory response
  • signal transduction
  • stress fiber
  • stress fiber assembly
  • transforming growth factor beta receptor signaling pathway
  • GO_0001725
  • GO_0003723
  • GO_0005634
  • GO_0005737
  • GO_0005829
  • GO_0005886
  • GO_0005912
  • GO_0005925
  • GO_0007160
  • GO_0007165
  • GO_0007179
  • GO_0007229
  • GO_0007267
  • GO_0015629
  • GO_0043149
  • GO_0045335
  • GO_0046872
  • GO_0050727
  • GO_0071346
ZC3H4
  • C19orf7
  • KIAA1064
Homo sapiens
9606
0
2
  • DNA-templated transcription, termination
  • RNA binding
  • chromosome
  • cytosol
  • lncRNA catabolic process
  • metal ion binding
  • negative regulation of DNA-templated transcription, elongation
  • negative regulation of lncRNA transcription
  • nuclear RNA surveillance
  • nucleoplasm
  • nucleus
  • promoter-specific chromatin binding
  • GO_0003723
  • GO_0005634
  • GO_0005654
  • GO_0005694
  • GO_0005829
  • GO_0006353
  • GO_0032785
  • GO_0046872
  • GO_0071027
  • GO_0110064
  • GO_0140744
  • GO_1990841
PTPA
  • PPP2R4
Homo sapiens
9606
0
1
  • ATP binding
  • ATPase complex
  • calcium channel complex
  • cytoplasm
  • extracellular exosome
  • mitotic spindle organization
  • negative regulation of phosphoprotein phosphatase activity
  • negative regulation of protein dephosphorylation
  • nucleoplasm
  • nucleus
  • peptidyl-prolyl cis-trans isomerase activity
  • positive regulation of apoptotic process
  • positive regulation of phosphoprotein phosphatase activity
  • positive regulation of protein dephosphorylation
  • protein homodimerization activity
  • protein phosphatase 2A binding
  • protein phosphatase regulator activity
  • protein phosphatase type 2A complex
  • protein tyrosine phosphatase activator activity
  • regulation of phosphoprotein phosphatase activity
  • signaling receptor binding
  • GO_0000159
  • GO_0003755
  • GO_0005102
  • GO_0005524
  • GO_0005634
  • GO_0005654
  • GO_0005737
  • GO_0007052
  • GO_0008160
  • GO_0019888
  • GO_0032515
  • GO_0032516
  • GO_0034704
  • GO_0035307
  • GO_0035308
  • GO_0042803
  • GO_0043065
  • GO_0043666
  • GO_0051721
  • GO_0070062
  • GO_1904949
RCC1
  • CHC1
Homo sapiens
9606
0
1
  • G1/S transition of mitotic cell cycle
  • cell division
  • chromatin
  • chromatin binding
  • chromosome
  • chromosome segregation
  • condensed nuclear chromosome
  • cytoplasm
  • guanyl-nucleotide exchange factor activity
  • histone binding
  • mitotic nuclear membrane reassembly
  • mitotic spindle organization
  • nuclear membrane
  • nucleoplasm
  • nucleosomal DNA binding
  • nucleosome binding
  • nucleus
  • protein heterodimerization activity
  • protein-containing complex
  • regulation of mitotic nuclear division
  • small GTPase binding
  • spindle assembly
  • sulfate binding
  • viral process
  • GO_0000082
  • GO_0000785
  • GO_0000794
  • GO_0003682
  • GO_0005085
  • GO_0005634
  • GO_0005654
  • GO_0005694
  • GO_0005737
  • GO_0007052
  • GO_0007059
  • GO_0007084
  • GO_0007088
  • GO_0016032
  • GO_0031267
  • GO_0031491
  • GO_0031492
  • GO_0031965
  • GO_0032991
  • GO_0042393
  • GO_0043199
  • GO_0046982
  • GO_0051225
  • GO_0051301
POLH
  • RAD30
  • RAD30A
  • XPV
Homo sapiens
9606
0
1
  • DNA repair
  • DNA replication
  • DNA synthesis involved in DNA repair
  • DNA-directed DNA polymerase activity
  • cellular response to UV-C
  • cytosol
  • damaged DNA binding
  • error-free translesion synthesis
  • error-prone translesion synthesis
  • metal ion binding
  • nucleoplasm
  • nucleus
  • pyrimidine dimer repair
  • regulation of DNA repair
  • replication fork
  • response to UV-C
  • response to radiation
  • site of double-strand break
  • GO_0000731
  • GO_0003684
  • GO_0003887
  • GO_0005634
  • GO_0005654
  • GO_0005657
  • GO_0005829
  • GO_0006260
  • GO_0006281
  • GO_0006282
  • GO_0006290
  • GO_0009314
  • GO_0010225
  • GO_0035861
  • GO_0042276
  • GO_0046872
  • GO_0070987
  • GO_0071494
AAK1
  • KIAA1048
Homo sapiens
9606
0
2
  • AP-2 adaptor complex binding
  • ATP binding
  • Notch binding
  • anchoring junction
  • cell leading edge
  • clathrin-coated pit
  • clathrin-coated vesicle
  • cytoplasm
  • cytosol
  • endocytosis
  • extrinsic component of plasma membrane
  • membrane organization
  • positive regulation of Notch signaling pathway
  • protein autophosphorylation
  • protein phosphorylation
  • protein serine kinase activity
  • protein serine/threonine kinase activity
  • protein stabilization
  • regulation of clathrin-dependent endocytosis
  • regulation of protein localization
  • terminal bouton
  • GO_0004674
  • GO_0005112
  • GO_0005524
  • GO_0005737
  • GO_0005829
  • GO_0005905
  • GO_0006468
  • GO_0006897
  • GO_0019897
  • GO_0030136
  • GO_0031252
  • GO_0032880
  • GO_0035612
  • GO_0043195
  • GO_0045747
  • GO_0046777
  • GO_0050821
  • GO_0061024
  • GO_0070161
  • GO_0106310
  • GO_2000369
KRT17
Homo sapiens
9606
0
1
  • cornified envelope
  • cytoskeleton
  • cytosol
  • epithelial cell differentiation
  • hair follicle morphogenesis
  • intermediate filament cytoskeleton
  • intermediate filament organization
  • keratin filament
  • keratinization
  • positive regulation of cell growth
  • positive regulation of hair follicle development
  • positive regulation of translation
  • structural molecule activity
  • GO_0001533
  • GO_0005198
  • GO_0005829
  • GO_0005856
  • GO_0030307
  • GO_0030855
  • GO_0031069
  • GO_0031424
  • GO_0045095
  • GO_0045109
  • GO_0045111
  • GO_0045727
  • GO_0051798
GTPBP1
Homo sapiens
9606
0
1
  • GTP binding
  • GTP metabolic process
  • GTPase activity
  • RNA binding
  • cytoplasmic exosome (RNase complex)
  • cytosol
  • immune response
  • membrane
  • positive regulation of mRNA catabolic process
  • signal transduction
  • translation elongation factor activity
  • translational elongation
  • GO_0000177
  • GO_0003723
  • GO_0003746
  • GO_0003924
  • GO_0005525
  • GO_0005829
  • GO_0006414
  • GO_0006955
  • GO_0007165
  • GO_0016020
  • GO_0046039
  • GO_0061014
Displaying entries 1 - 10 of 69329 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01