GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen April 24, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome March 22, 2023 (Version 83)
UniProt July 5, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs Disease Name GO Labels GO IDs
  • EDC3
559292
1
  • P-body
  • P-body assembly
  • cytoplasm
  • deadenylation-independent decapping of nuclear-transcribed mRNA
  • mRNA binding
  • nucleus
  • positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • GO_0000932
  • GO_0003729
  • GO_0005634
  • GO_0005737
  • GO_0031087
  • GO_0033962
  • GO_1900153
  • NAAA
9739
4
  • DNA-binding transcription factor binding
  • N-(long-chain-acyl)ethanolamine deacylase activity
  • N-acylethanolamine metabolic process
  • N-acylphosphatidylethanolamine metabolic process
  • N-acylsphingosine amidohydrolase activity
  • ceramidase activity
  • extrinsic component of membrane
  • fatty acid amide hydrolase activity
  • fatty acid metabolic process
  • lysosome
  • sphingosine metabolic process
  • GO_0005764
  • GO_0006631
  • GO_0006670
  • GO_0017040
  • GO_0017064
  • GO_0019898
  • GO_0047412
  • GO_0070291
  • GO_0070292
  • GO_0102121
  • GO_0140297
  • SLC25A16
9606
3
1
  • antiporter activity
  • coenzyme A biosynthetic process
  • coenzyme A transmembrane transporter activity
  • mitochondrial coenzyme A transmembrane transport
  • mitochondrial inner membrane
  • mitochondrial transport
  • mitochondrion
  • secondary active transmembrane transporter activity
  • GO_0005739
  • GO_0005743
  • GO_0006839
  • GO_0015228
  • GO_0015291
  • GO_0015297
  • GO_0015937
  • GO_1990559
  • Rho
237433
2
  • G protein-coupled receptor activity
  • light absorption
  • membrane
  • metal ion binding
  • photoreceptor activity
  • phototransduction
  • visual perception
  • GO_0004930
  • GO_0007601
  • GO_0007602
  • GO_0009881
  • GO_0016020
  • GO_0016037
  • GO_0046872
  • Kcnk17
201329
1
  • membrane
  • potassium channel activity
  • GO_0005267
  • GO_0016020
  • CACNA1C
59894
1
  • T-tubule
  • calmodulin binding
  • dendrite
  • metal ion binding
  • perikaryon
  • postsynaptic density membrane
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO_0005245
  • GO_0005516
  • GO_0005891
  • GO_0030315
  • GO_0030425
  • GO_0034765
  • GO_0043204
  • GO_0046872
  • GO_0098839
  • PLCD4
8790
1
  • calcium ion binding
  • intracellular signal transduction
  • lipid catabolic process
  • phosphatidylinositol phospholipase C activity
  • GO_0004435
  • GO_0005509
  • GO_0016042
  • GO_0035556
  • M2
311626
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • pore formation by virus in membrane of host cell
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • GO_0005216
  • GO_0015078
  • GO_0016020
  • GO_0020002
  • GO_0039521
  • GO_0039707
  • GO_0051259
  • GO_0055036
  • Pofut1
10116
2
  • Notch signaling pathway
  • angiogenesis
  • endoplasmic reticulum
  • fucose metabolic process
  • fucosyltransferase activity
  • heart development
  • membrane
  • nervous system development
  • peptide-O-fucosyltransferase activity
  • protein O-linked fucosylation
  • protein O-linked glycosylation
  • regulation of Notch signaling pathway
  • somitogenesis
  • GO_0001525
  • GO_0001756
  • GO_0005783
  • GO_0006004
  • GO_0006493
  • GO_0007219
  • GO_0007399
  • GO_0007507
  • GO_0008417
  • GO_0008593
  • GO_0016020
  • GO_0036066
  • GO_0046922
  • LOC105049190
51953
1
  • apoplast
  • cell wall biogenesis
  • cell wall organization
  • hydrolase activity, hydrolyzing O-glycosyl compounds
  • xyloglucan metabolic process
  • xyloglucan:xyloglucosyl transferase activity
  • GO_0004553
  • GO_0010411
  • GO_0016762
  • GO_0042546
  • GO_0048046
  • GO_0071555
Displaying entries 1 - 10 of 95752 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01