GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name ▲ UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites GO Labels GO IDs
  • HSD17B8
9606
  • (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity
  • NADH binding
  • androgen metabolic process
  • estradiol 17-beta-dehydrogenase [NAD(P)] activity
  • estrogen biosynthetic process
  • fatty acid biosynthetic process
  • mitochondrial envelope
  • mitochondrial matrix
  • oxidoreductase complex
  • plasma membrane
  • protein heterotetramerization
  • testosterone dehydrogenase (NAD+) activity
  • GO:0004303
  • GO:0005740
  • GO:0005759
  • GO:0005886
  • GO:0006633
  • GO:0006703
  • GO:0008209
  • GO:0047035
  • GO:0051290
  • GO:0070404
  • GO:0106386
  • GO:1990204
  • Hsd17b8
10090
  • (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity
  • NADH binding
  • androgen metabolic process
  • estradiol 17-beta-dehydrogenase [NAD(P)] activity
  • estrogen biosynthetic process
  • estrogen metabolic process
  • fatty acid biosynthetic process
  • membrane
  • mitochondrial envelope
  • mitochondrial matrix
  • mitochondrion
  • oxidoreductase complex
  • plasma membrane
  • protein heterotetramerization
  • testosterone dehydrogenase (NAD+) activity
  • GO:0004303
  • GO:0005739
  • GO:0005740
  • GO:0005759
  • GO:0005886
  • GO:0006633
  • GO:0006703
  • GO:0008209
  • GO:0008210
  • GO:0016020
  • GO:0047035
  • GO:0051290
  • GO:0070404
  • GO:0106386
  • GO:1990204
  • MMEN_LOCUS17070
238744
1
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005891
  • GO:0034765
  • MMEN_LOCUS13382
238744
1
  • collagen-containing extracellular matrix
  • extracellular matrix organization
  • extracellular region
  • metalloendopeptidase activity
  • proteolysis
  • zinc ion binding
  • GO:0004222
  • GO:0005576
  • GO:0006508
  • GO:0008270
  • GO:0030198
  • GO:0062023
  • MMEN_LOCUS18575
238744
2
  • aspartic-type endopeptidase activity
  • endosome
  • membrane
  • proteolysis
  • GO:0004190
  • GO:0005768
  • GO:0006508
  • GO:0016020
  • MMEN_LOCUS2947
238744
1
  • membrane
  • potassium channel activity
  • GO:0005267
  • GO:0016020
  • MMEN_LOCUS12488
238744
1
  • metal ion binding
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005891
  • GO:0034765
  • GO:0046872
  • TCMB3V08_LOCUS7217
61474
1
  • cartilage development
  • extracellular region
  • negative regulation of BMP signaling pathway
  • negative regulation of cell differentiation
  • GO:0005576
  • GO:0030514
  • GO:0045596
  • GO:0051216
  • C10orf90
9606
1
  • actin cytoskeleton
  • centriole
  • centrosome
  • cytoplasm
  • cytosol
  • microtubule binding
  • plasma membrane
  • protein polyubiquitination
  • protein stabilization
  • protein ubiquitination
  • regulation of centriole replication
  • ubiquitin protein ligase activity
  • GO:0000209
  • GO:0005737
  • GO:0005813
  • GO:0005814
  • GO:0005829
  • GO:0005886
  • GO:0008017
  • GO:0015629
  • GO:0016567
  • GO:0046599
  • GO:0050821
  • GO:0061630
  • UBE2O
9606
4
  • ATP binding
  • RNA binding
  • cytoplasm
  • cytosol
  • nuclear body
  • nucleoplasm
  • nucleus
  • positive regulation of BMP signaling pathway
  • protein K63-linked ubiquitination
  • protein monoubiquitination
  • retrograde transport, endosome to Golgi
  • ubiquitin conjugating enzyme activity
  • ubiquitin protein ligase activity
  • ubiquitin-protein transferase activity
  • GO:0003723
  • GO:0004842
  • GO:0005524
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0005829
  • GO:0006513
  • GO:0016604
  • GO:0030513
  • GO:0042147
  • GO:0061630
  • GO:0061631
  • GO:0070534
Displaying entries 1 - 10 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01