GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen, GlyConnect, GlycoProtDB and The O-GlcNAc Database. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Source	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 30, 2024
The O-GlcNAc Database	August 9, 2024
UniProt	October 29, 2024

Displaying entries **1 - 25** of **15733** in total

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UniProt ID	Protein Name	Gene Symbol	Organism	Taxonomy ID ▼	No. of Glycosylation Sites	No. of GlyTouCan IDs	GlyTouCan ID	Gene Ontology	Gene Ontology ID
P01112	GTPase HRas	HRAS HRAS1	Homo sapiens (human)	9606	1	1	G49108TO	G protein activity GDP binding GTP binding GTPase activity GTPase complex Golgi apparatus Golgi membrane MAPK cascade Ras protein signal transduction Schwann cell development T cell receptor signaling pathway T-helper 1 type immune response adipose tissue development animal organ morphogenesis cell surface receptor signaling pathway cellular response to gamma radiation cellular senescence chemotaxis cytoplasm cytosol defense response to protozoan endocytosis endoplasmic reticulum membrane fibroblast proliferation glutamatergic synapse insulin receptor signaling pathway intrinsic apoptotic signaling pathway myelination negative regulation of GTPase activity negative regulation of cell population proliferation negative regulation of gene expression negative regulation of neuron apoptotic process neuron apoptotic process nucleoplasm oncogene-induced cell senescence perinuclear region of cytoplasm plasma membrane positive regulation of ERK1 and ERK2 cascade positive regulation of GTPase activity positive regulation of JNK cascade positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial cell proliferation positive regulation of fibroblast proliferation positive regulation of miRNA metabolic process positive regulation of protein phosphorylation positive regulation of protein targeting to membrane positive regulation of ruffle assembly positive regulation of transcription by RNA polymerase II positive regulation of type II interferon production positive regulation of wound healing protein-membrane adaptor activity regulation of actin cytoskeleton organization regulation of cell cycle regulation of cell population proliferation regulation of long-term neuronal synaptic plasticity regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of transcription by RNA polymerase II signal transduction	GO:0000139 GO:0000165 GO:0001934 GO:0003924 GO:0003925 GO:0005525 GO:0005654 GO:0005737 GO:0005789 GO:0005794 GO:0005829 GO:0005886 GO:0006357 GO:0006897 GO:0006935 GO:0007165 GO:0007166 GO:0007265 GO:0008284 GO:0008285 GO:0008286 GO:0009887 GO:0010629 GO:0014044 GO:0019003 GO:0030335 GO:0032729 GO:0032956 GO:0034260 GO:0042088 GO:0042127 GO:0042552 GO:0042832 GO:0043406 GO:0043410 GO:0043495 GO:0043524 GO:0043547 GO:0045944 GO:0046330 GO:0048144 GO:0048146 GO:0048169 GO:0048471 GO:0050679 GO:0050852 GO:0051402 GO:0051726 GO:0060612 GO:0070374 GO:0071480 GO:0090303 GO:0090314 GO:0090398 GO:0090402 GO:0097193 GO:0098696 GO:0098978 GO:1900029 GO:1905360 GO:2000630
Q86VR7	V-set and immunoglobulin domain-containing protein 10-like	VSIG10L	Homo sapiens (human)	9606	12	1	G49108TO	membrane nucleoplasm	GO:0005654 GO:0016020
A0A0A7C4D2	MHC class I antigen (Fragment)	HLA-B	Homo sapiens (human)	9606	1	0
E9PKW6	Dickkopf WNT signaling pathway inhibitor 3 (Fragment)	DKK3	Homo sapiens (human)	9606	1	0		extracellular region negative regulation of Wnt signaling pathway	GO:0005576 GO:0030178
A0A0S4T1R4	MHC class I antigen	HLA-C	Homo sapiens (human)	9606	1	0		ER to Golgi transport vesicle membrane antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib early endosome membrane external side of plasma membrane extracellular space immune response lumenal side of endoplasmic reticulum membrane peptide antigen binding phagocytic vesicle membrane positive regulation of T cell mediated cytotoxicity recycling endosome membrane signaling receptor binding	GO:0001916 GO:0002476 GO:0002486 GO:0005102 GO:0005615 GO:0006955 GO:0009897 GO:0012507 GO:0030670 GO:0031901 GO:0042605 GO:0055038 GO:0098553
Q5JSG7	Proprotein convertase subtilisin/kexin type 5 (Fragment)	PCSK5	Homo sapiens (human)	9606	1	0		Golgi apparatus membrane proteolysis serine-type endopeptidase activity	GO:0004252 GO:0005794 GO:0006508 GO:0016020
Q2WGJ8	Cation channel sperm-associated auxiliary subunit TMEM249	TMEM249 C8orfK29	Homo sapiens (human)	9606	1	1	G49108TO	CatSper complex sperm principal piece	GO:0036128 GO:0097228
Q12788	Transducin beta-like protein 3	TBL3 SAZD	Homo sapiens (human)	9606	3	1	G49108TO	90S preribosome RNA binding U3 snoRNA binding endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleolus nucleoplasm ribosomal small subunit biogenesis small-subunit processome	GO:0000472 GO:0000480 GO:0003723 GO:0005654 GO:0005730 GO:0030686 GO:0032040 GO:0034511 GO:0042274
P01850	T cell receptor beta constant 1	TRBC1	Homo sapiens (human)	9606	1	0		T cell receptor signaling pathway adaptive immune response alpha-beta T cell activation alpha-beta T cell receptor complex immune response membrane plasma membrane	GO:0002250 GO:0005886 GO:0006955 GO:0016020 GO:0042105 GO:0046631 GO:0050852
A0A0S2Z3T4	receptor protein-tyrosine kinase (Fragment)	FGFR1	Homo sapiens (human)	9606	2	0		ATP binding animal organ development cytoplasmic vesicle cytosol fibroblast growth factor receptor activity nucleus plasma membrane positive regulation of cell population proliferation	GO:0005007 GO:0005524 GO:0005634 GO:0005829 GO:0005886 GO:0008284 GO:0031410 GO:0048513
D1G0T2	MHC class I antigen (Fragment)	HLA-B	Homo sapiens (human)	9606	1	0
Q2KJY2	Kinesin-like protein KIF26B	KIF26B	Homo sapiens (human)	9606	4	1	G49108TO	ATP binding cytoplasm establishment of cell polarity microtubule binding microtubule motor activity microtubule-based movement microtubule positive regulation of cell-cell adhesion ureteric bud invasion	GO:0003777 GO:0005524 GO:0005737 GO:0005874 GO:0007018 GO:0008017 GO:0022409 GO:0030010 GO:0072092
Q16820	Meprin A subunit beta	MEP1B	Homo sapiens (human)	9606	12	0		extracellular region identical protein binding inflammatory response meprin A complex metalloendopeptidase activity plasma membrane proteolysis zinc ion binding	GO:0004222 GO:0005576 GO:0005886 GO:0006508 GO:0006954 GO:0008270 GO:0017090 GO:0042802
C6JSY3	MHC class I antigen (Fragment)	HLA-C	Homo sapiens (human)	9606	1	0
E5DCP4	MHC class I antigen (Fragment)	HLA-C	Homo sapiens (human)	9606	1	0		antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib external side of plasma membrane extracellular space immune response peptide antigen binding positive regulation of T cell mediated cytotoxicity signaling receptor binding	GO:0001916 GO:0002476 GO:0002486 GO:0005102 GO:0005615 GO:0006955 GO:0009897 GO:0042605
Q9H9H4	Vacuolar protein sorting-associated protein 37B	VPS37B	Homo sapiens (human)	9606	1	1	G83460ZZ	ESCRT I complex calcium-dependent protein binding cytoplasm endosome membrane endosome extracellular exosome late endosome membrane macroautophagy membrane fission midbody multivesicular body assembly plasma membrane positive regulation of viral budding via host ESCRT complex protein targeting to membrane protein targeting to vacuole protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway viral budding via host ESCRT complex viral release from host cell	GO:0000813 GO:0005737 GO:0005768 GO:0005886 GO:0006612 GO:0006623 GO:0010008 GO:0016236 GO:0019076 GO:0030496 GO:0031902 GO:0036258 GO:0039702 GO:0043162 GO:0043328 GO:0048306 GO:0070062 GO:0090148 GO:1903774
W1I435	MHC class I antigen (Fragment)	HLA-C	Homo sapiens (human)	9606	1	0		ER to Golgi transport vesicle membrane antigen processing and presentation cell surface early endosome membrane immune response lumenal side of endoplasmic reticulum membrane phagocytic vesicle membrane recycling endosome membrane	GO:0006955 GO:0009986 GO:0012507 GO:0019882 GO:0030670 GO:0031901 GO:0055038 GO:0098553
Q8IZQ1	WD repeat and FYVE domain-containing protein 3	WDFY3 KIAA0993	Homo sapiens (human)	9606	6	2	G41247ZX G49108TO	1-phosphatidylinositol binding PML body aggrephagy autophagosome membrane autophagosome axon cytoplasm cytosol inclusion body membrane metal ion binding nuclear envelope nuclear membrane nucleolus nucleoplasm perikaryon plasma membrane	GO:0000421 GO:0005545 GO:0005635 GO:0005654 GO:0005730 GO:0005737 GO:0005776 GO:0005829 GO:0005886 GO:0016020 GO:0016234 GO:0016605 GO:0030424 GO:0031965 GO:0035973 GO:0043204 GO:0046872
A0A2K4XGM2	MHC class I antigen	HLA-C	Homo sapiens (human)	9606	1	0		ER to Golgi transport vesicle membrane antigen processing and presentation cell surface early endosome membrane immune response lumenal side of endoplasmic reticulum membrane phagocytic vesicle membrane recycling endosome membrane	GO:0006955 GO:0009986 GO:0012507 GO:0019882 GO:0030670 GO:0031901 GO:0055038 GO:0098553
Q9C0B5	Palmitoyltransferase ZDHHC5	ZDHHC5 KIAA1748 ZNF375	Homo sapiens (human)	9606	5	2	G44753VC G57321FI	GABA-ergic synapse Golgi membrane dendrite glutamatergic synapse innate immune response lipid transport membrane nucleoplasm palmitoyltransferase activity phagocytic vesicle plasma membrane positive regulation of NLRP3 inflammasome complex assembly positive regulation of pattern recognition receptor signaling pathway positive regulation of protein localization to phagocytic vesicle positive regulation of protein localization to plasma membrane positive regulation of pyroptosis postsynaptic specialization, intracellular component protein localization to plasma membrane protein palmitoylation protein-cysteine S-palmitoyltransferase activity regulation of postsynaptic membrane neurotransmitter receptor levels	GO:0000139 GO:0005654 GO:0005886 GO:0006869 GO:0016020 GO:0016409 GO:0018345 GO:0019706 GO:0030425 GO:0045087 GO:0045335 GO:0062208 GO:0072659 GO:0098978 GO:0098982 GO:0099072 GO:0099091 GO:0140639 GO:1900227 GO:1903078 GO:1905171
A0A5H2UVS5	MHC class I antigen	HLA-C	Homo sapiens (human)	9606	1	0		ER to Golgi transport vesicle membrane antigen processing and presentation cell surface early endosome membrane immune response lumenal side of endoplasmic reticulum membrane phagocytic vesicle membrane recycling endosome membrane	GO:0006955 GO:0009986 GO:0012507 GO:0019882 GO:0030670 GO:0031901 GO:0055038 GO:0098553
D3Y5Z0	MHC class I antigen (Fragment)	HLA-B	Homo sapiens (human)	9606	1	0		antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib external side of plasma membrane extracellular space immune response peptide antigen binding positive regulation of T cell mediated cytotoxicity signaling receptor binding	GO:0001916 GO:0002476 GO:0002486 GO:0005102 GO:0005615 GO:0006955 GO:0009897 GO:0042605
M9P9L6	MHC class I antigen (Fragment)	HLA-C	Homo sapiens (human)	9606	1	0
A0A0A7C5Z7	MHC class I antigen (Fragment)	HLA-C	Homo sapiens (human)	9606	1	0
O00507	Ubiquitin carboxyl-terminal hydrolase 9Y	USP9Y DFFRY	Homo sapiens (human)	9606	1	1	G49108TO	BMP signaling pathway cell migration co-SMAD binding cysteine-type deubiquitinase activity cysteine-type peptidase activity cytoplasm cytosol metal ion binding nucleus protein deubiquitination proteolysis spermatogenesis transforming growth factor beta receptor signaling pathway	GO:0004843 GO:0005634 GO:0005737 GO:0005829 GO:0006508 GO:0007179 GO:0007283 GO:0008234 GO:0016477 GO:0016579 GO:0030509 GO:0046872 GO:0070410

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