GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Species	No. of Glycosylation Sites	No. of GlyTouCan IDs	Disease Name ▲
Lysosomal protective protein	P10619	CTSA	PPGB	Homo sapiens	5	7	Galactosialidosis
Lysosomal acid glucosylceramidase	P04062	GBA1	GBA GC GLUC	Homo sapiens	8	29	Gaucher disease, type I Gaucher disease, type II Gaucher disease, type II, neuronopathic form, classic type Gaucher disease, type II, perinatal lethal form Gaucher disease, type III Gaucher disease, type IIIC
Alpha-L-iduronidase	P35475	IDUA		Homo sapiens	6	5	Hurler syndrome Hurler-Scheie syndrome Scheie syndrome
Galactocerebrosidase	P54803	GALC		Homo sapiens	6	1	Krabbe disease Krabbe disease, infantile form Krabbe disease, late-onset form
Xylosyl- and glucuronyltransferase LARGE1	O95461	LARGE1	KIAA0609 LARGE	Homo sapiens	4		LARGE-CDG (cong. muscular dystrophy spectrum)
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe	Q8NES3	LFNG		Homo sapiens	1	1	LFNG-CDG
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	O60568	PLOD3		Homo sapiens	6	14	Lysyl hydroxylase 3 deficiency
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2		Homo sapiens	8	3	MGAT2-CDG
Mannose-P-dolichol utilization defect 1 protein	O75352	MPDU1		Homo sapiens		1	MPDU1-CDG
Mannose-6-phosphate isomerase	P34949	MPI	PMI1	Homo sapiens		1	MPI-CDG