GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Species	No. of Glycosylation Sites	No. of GlyTouCan IDs	Disease Name ▲
Carbohydrate sulfotransferase 6	Q9GZX3	CHST6		Homo sapiens	4	1	Macular corneal dystrophy
Arylsulfatase B	P15848	ARSB		Homo sapiens	7	4	Maroteaux-Lamy syndrome, intermediate form Maroteaux-Lamy syndrome, mild form Maroteaux-Lamy syndrome, severe form Mucopolysaccharidosis VI
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase	Q11203	ST3GAL3	SIAT6	Homo sapiens	2		Mental retardation, autosomal recessive 12
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	Q9UKM7	MAN1B1		Homo sapiens	17	4	Mental retardation, autosomal recessive 15
Arylsulfatase A	P15289	ARSA		Homo sapiens	4	28	Metachromatic leukodystrophy Metachromatic leukodystrophy, adult form Metachromatic leukodystrophy, infantile form Metachromatic leukodystrophy, juvenile form
N-acetylgalactosamine-6-sulfatase	P34059	GALNS		Homo sapiens	3	7	Morquio syndrome A
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta	Q3T906	GNPTAB	GNPTA KIAA1208	Homo sapiens	40	9	Mucolipidosis II (alpha/beta) Mucolipidosis III (alpha/beta)
Iduronate 2-sulfatase	P22304	IDS	SIDS	Homo sapiens	8	3	Mucopolysaccharidosis II
Beta-glucuronidase	P08236	GUSB		Homo sapiens	7	18	Mucopolysaccharidosis VII
GPI ethanolamine phosphate transferase 1	O95427	PIGN	MCD4	Homo sapiens	4	1	Multiple congenital anomalies-hypotonia-seizures syndrome 1