GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Gene Symbol Aliases	Species	No. of Glycosylation Sites	No. of GlyTouCan IDs	Disease Name ▲
Lysosomal alpha-glucosidase	P10253	GAA		Homo sapiens	19	32	Pompe disease Pompe disease, infantile-onset form Pompe disease, late-onset form
Protein transport protein Sec23B	Q15437	SEC23B		Homo sapiens	14	1	SEC23B-CDG
CMP-sialic acid transporter	P78382	SLC35A1		Homo sapiens		1	SLC35A1-CDG
Lactosylceramide alpha-2,3-sialyltransferase	Q9UNP4	ST3GAL5	SIAT9	Homo sapiens	3		ST3GAL5-CDG
Beta-hexosaminidase subunit beta	P07686	HEXB		Homo sapiens	6	14	Sandhoff disease Sandhoff disease, adult form Sandhoff disease, infantile form Sandhoff disease, juvenile form
N-sulphoglucosamine sulphohydrolase	P51688	SGSH	HSS	Homo sapiens	6	2	Sanfilippo syndrome A
Alpha-N-acetylglucosaminidase	P54802	NAGLU	UFHSD1	Homo sapiens	7	40	Sanfilippo syndrome B
Heparan-alpha-glucosaminide N-acetyltransferase	Q68CP4	HGSNAT	TMEM76	Homo sapiens	5	5	Sanfilippo syndrome C
N-acetylglucosamine-6-sulfatase	P15586	GNS		Homo sapiens	21	30	Sanfilippo syndrome D
Alpha-N-acetylgalactosaminidase	P17050	NAGA		Homo sapiens	5	85	Schindler disease, type I Schindler disease, type II