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Integrin beta-3

Summary

UniProt ID

O54890

Gene Symbol

Itgb3

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003145

GlyConnect

2405

GlyGen

O54890

PubChem

O54890

RaftProt

O54890

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Cell junction
Cell membrane
Cell projection
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Phosphoprotein
Postsynaptic cell membrane
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

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GO Term
negative chemotaxis
regulation of release of sequestered calcium ion into cytosol
cellular response to xenobiotic stimulus
blood coagulation, fibrin clot formation
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
heterotypic cell-cell adhesion
substrate adhesion-dependent cell spreading
apolipoprotein A-I-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade

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GO Term
nucleus
cell-cell junction
melanosome
integrin complex
external side of plasma membrane
cell surface
ruffle membrane
integrin alpha9-beta1 complex
integrin alphav-beta3 complex
alphav-beta3 integrin-PKCalpha complex

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GO Term
protease binding
enzyme binding
metal ion binding
vascular endothelial growth factor receptor 2 binding
extracellular matrix binding
fibrinogen binding
C-X3-C chemokine binding
insulin-like growth factor I binding
identical protein binding
fibronectin binding

Annotation information from UniProt.

Sequence

MRAQWPGQLWAALLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDETLSQGSPRCNLKENLLKDNCAPESIEFPVSEAQILEARPLSSKGSGSSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMYISPPQAIKNPCYNMKNACLPMFGYKHVLTLTDQVSRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGHCHIGTDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTVSFSIEAKVRGCPQEKEQSFTIKPVGFKDSLTVQVTFDCDCACQAFAQPSSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKECVECKKFNRGTLHEENTCSRYCRDDIEQVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDTSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
477		23002422
584		22823882
679		17406563 22823882

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 14** of 14 in total

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Pathway Name	Organism
Syndecan interactions	Mus musculus
TGF-beta receptor signaling activates SMADs	Mus musculus
VEGFA-VEGFR2 Pathway	Mus musculus
p130Cas linkage to MAPK signaling for integrins	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements