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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Tissue alpha-L-fucosidase
Summary
- UniProt ID
- P04066
- Gene Symbol
-
- FUCA1
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011351
- GlyConnect
- GlyGen
- P04066
- PubChem
- P04066
- SwissLipids
- The Human Metabolome Database
- HMDBP00875
- The O-GlcNAc Database
- P04066
- O-GlcNAcAtlas
- P04066
Annotation
- Keyword
-
- 3D-structure
- Disease variant
- Glycoprotein
- Glycosidase
- Lipid metabolism
- Lysosome
- Phosphoprotein
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| glycosaminoglycan catabolic process |
| fucose metabolic process |
| glycolipid catabolic process |
| glycoside catabolic process |
| GO Term |
|---|
| extracellular exosome |
| azurophil granule lumen |
| lysosomal lumen |
| extracellular region |
| cytoplasm |
| lysosome |
| intracellular membrane-bounded organelle |
| GO Term |
|---|
| alpha-L-fucosidase activity |
Sequence
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Neutrophil degranulation | Homo sapiens |
| Reactions specific to the complex N-glycan synthesis pathway | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11712 | lipoatrophic diabetes mellitus | |
| DOID:11832 | visual epilepsy | |
| DOID:11934 | head and neck cancer | |
| DOID:12697 | locked-in syndrome | |
| DOID:12798 | mucopolysaccharidosis | |
| DOID:12799 | mucopolysaccharidosis II | |
| DOID:12800 | mucopolysaccharidosis VI | |
| DOID:12801 | mucopolysaccharidosis III | |
| DOID:12802 | mucopolysaccharidosis I | |
| DOID:12804 | mucopolysaccharidosis IV |
