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Glycan Structure Repository
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Glycoconjugate Repository
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Glycomics MS raw data Repository
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Glycomics MS Repository for glycan annotations from GlycoWorkbench
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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Decorin
Summary
- UniProt ID
- P07585
- Gene Symbol
-
- DCN
- SLRR1B
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0015592
- GlyConnect
- GlyGen
- P07585
- PubChem
- P07585
- RaftProt
- P07585
Annotation
- Keyword
-
- Alternative splicing
- Corneal dystrophy
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Leucine-rich repeat
- Proteoglycan
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| collagen-containing extracellular matrix |
| Golgi lumen |
| lysosomal lumen |
| GO Term |
|---|
| RNA binding |
| glycosaminoglycan binding |
| extracellular matrix binding |
| extracellular matrix structural constituent conferring compression resistance |
Sequence
MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 262 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Homo sapiens |
| CS/DS degradation | Homo sapiens |
| Chondroitin sulfate biosynthesis | Homo sapiens |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | Homo sapiens |
| Defective B3GAT3 causes JDSSDHD | Homo sapiens |
| Defective B4GALT7 causes EDS, progeroid type | Homo sapiens |
| Defective CHST14 causes EDS, musculocontractural type | Homo sapiens |
| Defective CHST3 causes SEDCJD | Homo sapiens |
| Defective CHSY1 causes TPBS | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070137 | autosomal recessive cutis laxa type IIB | |
| DOID:0070138 | autosomal recessive cutis laxa type IIIB | |
| DOID:0070140 | autosomal recessive cutis laxa type IIC | |
| DOID:0070141 | autosomal recessive cutis laxa type II classic type | |
| DOID:0070142 | autosomal dominant cutis laxa | |
| DOID:0070247 | autosomal dominant Emery-Dreifuss muscular dystrophy 2 | |
| DOID:0080001 | bone disease | |
| DOID:0080041 | hypochondroplasia | |
| DOID:0080047 | pseudoachondroplasia | |
| DOID:0080055 | achondrogenesis type IB |
