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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Folate receptor alpha
Summary
- UniProt ID
- P15328
- Gene Symbol
-
- FOLR1
- FOLR
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011537
- GlyConnect
- GlyGen
- P15328
- PubChem
- P15328
- The Human Metabolome Database
- HMDBP02326
- The O-GlcNAc Database
- P15328
- RaftProt
- P15328
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Gene Ontology (GO)
| GO Term |
|---|
| fusion of sperm to egg plasma membrane involved in single fertilization |
| folic acid transport |
| axon regeneration |
| sperm-egg recognition |
| regulation of canonical Wnt signaling pathway |
| GO Term |
|---|
| endosome |
| endoplasmic reticulum membrane |
| external side of plasma membrane |
| cell surface |
| ER to Golgi transport vesicle membrane |
| endoplasmic reticulum-Golgi intermediate compartment membrane |
| GO Term |
|---|
| folic acid receptor activity |
| folic acid binding |
| signaling receptor activity |
Sequence
MAQRMTTQLLLLLVWVAVVGEAQTRIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMSGAGPWAAWPFLLSLALMLLWLLS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| COPI-mediated anterograde transport | Homo sapiens |
| COPII-mediated vesicle transport | Homo sapiens |
| Cargo concentration in the ER | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3565 | meningioma | |
| DOID:3571 | liver cancer | |
| DOID:363 | uterine cancer | |
| DOID:3744 | cervical squamous cell carcinoma | |
| DOID:3772 | intraventricular meningioma | |
| DOID:3829 | pituitary adenoma | |
| DOID:3861 | medullomyoblastoma | |
| DOID:3864 | adult medulloblastoma | |
| DOID:3868 | melanotic medulloblastoma | |
| DOID:3869 | childhood medulloblastoma |
