Prothrombin

Summary
UniProt ID
P19221
Gene Symbol
  • F2
  • Cf2
Organism
Mus musculus (house mouse)
External Links
GlycoProtDB
GPDB0003459
GlyGen
P19221
PubChem
P19221
Annotation
Keyword
  • 3D-structure
  • Acute phase
  • Blood coagulation
  • Calcium
  • Cleavage on pair of basic residues
  • Disulfide bond
  • Gamma-carboxyglutamic acid
  • Glycoprotein
  • Kringle
  • Reference proteome
  • Repeat
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Sequence
MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEEAFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHKPEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSPPLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAGQPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEKELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKRWIQKVIDQFG
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
122
144
553
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying entry 11 - 11 of 11 in total
Pathway Name Organism
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Mus musculus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024