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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
High affinity immunoglobulin gamma Fc receptor I
Summary
- UniProt ID
- P26151
- Gene Symbol
-
- Fcgr1
- Fcg1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003516
- PubChem
- P26151
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- Glycoprotein
- IgG-binding protein
- Immunoglobulin domain
- Innate immunity
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| phagocytosis, recognition |
| phagocytosis, engulfment |
| positive regulation of phagocytosis, engulfment |
| antibody-dependent cellular cytotoxicity |
| positive regulation of type IIa hypersensitivity |
| GO Term |
|---|
| external side of plasma membrane |
| GO Term |
|---|
| IgG receptor activity |
| high-affinity IgG receptor activity |
| IgG binding |
| leukotriene receptor binding |
Sequence
MILTSFGDDMWLLTTLLLWVPVGGEVVNATKAVITLQPPWVSIFQKENVTLWCEGPHLPGDSSTQWFINGTAVQISTPSYSIPEASFQDSGEYRCQIGSSMPSDPVQLQIHNDWLLLQASRRVLTEGEPLALRCHGWKNKLVYNVVFYRNGKSFQFSSDSEVAILKTNLSHSGIYHCSGTGRHRYTSAGVSITVKELFTTPVLRASVSSPFPEGSLVTLNCETNLLLQRPGLQLHFSFYVGSKILEYRNTSSEYHIARAEREDAGFYWCEVATEDSSVLKRSPELELQVLGPQSSAPVWFHILFYLSVGIMFSLNTVLYVKIHRLQREKKYNLEVPLVSEQGKKANSFQQVRSDGVYEEVTATASQTTPKEAPDGPRSSVGDCGPEQPEPLPPSDSTGAQTSQS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cross-presentation of soluble exogenous antigens (endosomes) | Mus musculus |
| FCGR activation | Mus musculus |
| Regulation of actin dynamics for phagocytic cup formation | Mus musculus |
| Role of phospholipids in phagocytosis | Mus musculus |
