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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Palmitoyl-protein thioesterase 1
Summary
- UniProt ID
- P50897
- Gene Symbol
-
- PPT1
- CLN1
- PPT
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011719
- GlyConnect
- GlyGen
- P50897
- PubChem
- P50897
- The Human Metabolome Database
- HMDBP01050
- The O-GlcNAc Database
- P50897
- O-GlcNAcAtlas
- P50897
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Neuronal ceroid lipofuscinosis
- Reference proteome
- Secreted
- Signal
- Vision
- Gene Ontology (GO)
| GO Term |
|---|
| intracellular membrane-bounded organelle |
| dendrite |
| neuronal cell body |
| extracellular exosome |
| GO Term |
|---|
| palmitoyl-(protein) hydrolase activity |
| lysophosphatidic acid binding |
| sulfatide binding |
| long-chain acyl-CoA hydrolase activity |
Sequence
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fatty acyl-CoA biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:289 | endometriosis | |
| DOID:3068 | glioblastoma | |
| DOID:3070 | high grade glioma | |
| DOID:3074 | giant cell glioblastoma | |
| DOID:308 | early myoclonic encephalopathy | |
| DOID:3149 | keratoacanthoma | |
| DOID:3211 | lysosomal storage disease | |
| DOID:331 | central nervous system disease | |
| DOID:3459 | breast carcinoma | |
| DOID:3535 | Unverricht-Lundborg syndrome |
